Graft‐versus‐host disease after pediatric liver transplantation: A diagnostic challenge

2021 ◽  
Author(s):  
Rabab Ali Al Attas ◽  
Razan M. Bader ◽  
Miral Mashhour ◽  
Zuhoor A. AlQahtani ◽  
Amani Mohammed ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Graft Versus Host Disease ◽  
Pediatric Liver Transplantation ◽  
Diagnostic Challenge ◽  
Host Disease ◽  
Graft Versus Host ◽  
Pediatric Liver

Acute central nervous system graft-versus-host-disease after liver transplantation

2021 ◽  
pp. 101521
Author(s):  
Valérie Massey ◽  
Véronique Martel ◽  
Dang Khoa Nguyen ◽  
Lambert Busque ◽  
Hugo Chapdelaine ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Liver Transplantation ◽  
Nervous System ◽  
Graft Versus Host Disease ◽  
Host Disease ◽  
Graft Versus Host

High Levels of Donor‐derived Cell‐Free DNA in a Case of Graft‐Versus‐Host‐Disease Following Liver Transplantation

2021 ◽  
Author(s):  
Duncan Lewis ◽  
Renata Glehn‐Ponsirenas ◽  
Natali Gulbahce ◽  
Leah J. Hooey ◽  
Joanna M. Chaffin ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Graft Versus Host Disease ◽  
Cell Free Dna ◽  
Host Disease ◽  
Graft Versus Host ◽  
Free Dna

Incidence and Risk Factors for Fatal Graft-versus-host Disease After Liver Transplantation

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Toshihiro Kitajima ◽  
Matthew Henry ◽  
Tommy Ivanics ◽  
Sirisha Yeddula ◽  
Kelly Collins ◽  
...  
Keyword(s):  
Risk Factors ◽  
Liver Transplantation ◽  
Graft Versus Host Disease ◽  
Host Disease ◽  
Graft Versus Host

Late onset of severe graft‐versus‐host disease following liver transplantation

2006 ◽  
Vol 16 (3-4) ◽  
pp. 250-253 ◽  
Author(s):  
Beicheng Sun ◽  
Chaochen Zhao ◽  
Yongxiang Xia ◽  
Guoqiang Li ◽  
Feng Cheng ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Graft Versus Host Disease ◽  
Late Onset ◽  
Host Disease ◽  
Graft Versus Host

Graft versus Host Disease after Orthotopic Liver Transplantation Documented by Analysis of Short Tandem Repeat Polymorphisms

Digestion ◽  
2006 ◽  
Vol 74 (3-4) ◽  
pp. 169-173 ◽  
Author(s):  
M. Schöniger-Hekele ◽  
C. Müller ◽  
L. Kramer ◽  
E. Dauber ◽  
W.R. Mayr ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Orthotopic Liver Transplantation ◽  
Graft Versus Host Disease ◽  
Tandem Repeat ◽  
Short Tandem Repeat ◽  
Host Disease ◽  
Graft Versus Host ◽  
Short Tandem

Two Cases and a Review of Graft-Versus-Host Disease and the Role of Hepatitis C Treatment in Liver Transplant Patients

2018 ◽  
Vol 28 (3) ◽  
pp. 267-270 ◽  
Author(s):  
Sonali D. Advani ◽  
Anoma Nellore ◽  
Giorgos Hadjivassiliou ◽  
Devin E. Eckhoff ◽  
Donna Salzman ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Hepatitis C ◽  
Graft Versus Host Disease ◽  
High Dose ◽  
Solid Organ ◽  
Hcv Treatment ◽  
Host Disease ◽  
Graft Versus Host ◽  
Transplant Patients

Graft-versus-host disease (GvHD) is a rare but fatal complication after solid organ transplantation arising in 1% to 2% of cases. We report 2 cases of GvHD after orthotopic liver transplantation. Both patients had a history of hepatitis C virus (HCV) infection prior to transplantation. Both cases presented between 1 and 4 months after transplantation with rash, pancytopenia, and/or diarrhea. Our second case also developed oral and ocular manifestations after liver transplantation, which are more commonly described after stem cell transplantation. Diagnosis in both cases was made by clinical presentation in conjunction with histopathology and flow cytometry. Both patients were treated by increasing immunosuppression with tacrolimus and high-dose steroids. Response to treatment differed based on the degree of pancytopenia. Our case report is distinguished by several factors such as the context of GvHD presentation and the role of HCV treatment. Diagnosis of GvHD is difficult and often delayed due to nonspecific presentation that overlaps with other conditions. Furthermore, the relation between HCV treatment and potential initiation of GvHD in solid organ transplant patients is unclear.

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