Acute kidney injury and chronic kidney disease after combined heart‐liver transplant in patients with congenital heart disease: A retrospective case series

2020 ◽  
Vol 24 (7) ◽  
Author(s):  
Angela Lee ◽  
Waldo Concepcion ◽  
Selena Gonzales ◽  
Scott M. Sutherland ◽  
Seth A. Hollander
Keyword(s):  
Chronic Kidney Disease ◽  
Acute Kidney Injury ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Kidney Disease ◽  
Liver Transplant ◽  
Congenital Heart ◽  
Case Series ◽  
Kidney Injury ◽  
Retrospective Case

scholarly journals Cardiac surgery in patients with congenital heart disease is associated with acute kidney injury and the risk of chronic kidney disease

2017 ◽  
Vol 92 (3) ◽  
pp. 751-756 ◽  
Author(s):  
Nicolas L. Madsen ◽  
Stuart L. Goldstein ◽  
Trine Frøslev ◽  
Christian F. Christiansen ◽  
Morten Olsen
Keyword(s):  
Chronic Kidney Disease ◽  
Acute Kidney Injury ◽  
Congenital Heart Disease ◽  
Cardiac Surgery ◽  
Heart Disease ◽  
Kidney Disease ◽  
Congenital Heart ◽  
Kidney Injury

Preoperative Albumin Level is not Associated with Acute Kidney Injury After Pediatric Cardiac Surgery: A Retrospective Cohort

2021 ◽  
Author(s):  
Fatma Ukil Isildak ◽  
Yasemin Yavuz ◽  
Omer Faruk Savluk ◽  
Nihat Cine ◽  
Ufuk Uslu
Keyword(s):  
Acute Kidney Injury ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Retrospective Cohort ◽  
Congenital Heart ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Kidney Injury ◽  
Open Heart ◽  
Preoperative Albumin

Objectives: This study aimed to evaluate whether the development of acute kidney injury (AKI) was associated with preoperative albumin/prealbumin levels and other clinical features in pediatric patients who underwent open-heart surgery for congenital heart disease. Patients and Methods: In this retrospective cohort, patients aged between 1 – 60 months who underwent open-heart surgery (complete correction surgery) with a diagnosis of congenital heart disease at the XXXXXX, between January 1, 2018 - December 31, 2020, were retrospectively included (n = 100). Patient demographics, diagnoses, surgical characteristics, and laboratory findings were recorded and analyzed. Results: Mean age was 13.63 ± 12.05 (range 1.5 - 60) months. eGFR was decreased by more than 50% in 13% of the cases. Compared to the preoperative period, it was found that urea (24th and 48th hour) and creatinine levels increased significantly (p< 0.001, for each), and eGFR decreased significantly in the postoperative period (p< 0.001). Linear regression for eGFR value revealed that longer aortic cross-clamp time (ACCT) was associated with a greater decrease in eGFR (p= 0.046). Other variables included in the model, age (p= 0.128), gender (p= 0.358), RACHS (p= 0.865), body mass index (p= 0.862), prealbumin (p= 0.313), albumin (p= 0.806) and duration of cardiopulmonary bypass (p= 0.921) were found to be non-significant. Conclusion: While there was no relationship between eGFR and preoperative albumin/prealbumin levels in patients who underwent cardiac surgery due to congenital heart disease, longer ACCT was found to be associated with decreased eGFR.

Chronic Kidney Disease in Adolescents after Surgery for Congenital Heart Disease

2020 ◽  
Vol 10 (5) ◽  
pp. 353-361
Author(s):  
Mirela Bojan ◽  
Laurence Pieroni ◽  
Cristian Mirabile ◽  
Marc Froissart ◽  
Damien Bonnet
Keyword(s):  
Chronic Kidney Disease ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Kidney Disease ◽  
Cystatin C ◽  
Congenital Heart ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Orthostatic Proteinuria ◽  
Age Range

Background: The onset of chronic kidney disease (CKD) is an important prognostic factor in young adults with congenital heart disease (CHD). Although it is likely that CKD is manifest early in CHD patients, the prevalence among adolescents is still unknown. The National Kidney Foundation’s Kidney Disease Improving Global Outcomes guidelines 2012 recommend new equations for the estimated glomerular filtration rate (eGFR) and highlight the importance of albuminuria for CKD screening. The objective of the present study was to estimate the prevalence of CKD in CHD adolescents. Methods: This observational cross-sectional study included 115 patients aged 10–18 years attending the cardiologic outpatient clinic at our institution as a follow-up after cardiac surgery in infancy related to various CHDs. CKD assessment used the CKD criteria 2012, including eGFR equations based on serum creatinine and cystatin C, and measurement of albuminuria. Results: No patient had an eGFR <60 mL min–1 1.73 m–2. However, 28.7% of all patients (95% CI 20.7–37.9) had eGFRbetween 60 and 89 mL min–1 1.73 m–2 when estimated by the bedside Schwartz creatinine-based equation,and 17.4% (95% CI 11.2–24.1) had eGFRbetween 60 and 89 mL min–1 1.73 m–2 when estimated by the Zappitelli equation, combining creatinine and cystatin C. Of all patients, 20.0% (95% CI 12.1–26.7) had orthostatic proteinuria, and none had persistent albuminuria. Conclusions: There was no evidence of CKD in the present population aged 10–18 years. The significance of an eGFR between 60 and 90 mL min–1 1.73 m–2 is not concordant for this age range and requires further investigations.

scholarly journals Mild postoperative acute kidney injury and outcomes after surgery for congenital heart disease

2013 ◽  
Vol 146 (1) ◽  
pp. 146-152 ◽  
Author(s):  
Marnie L. Taylor ◽  
Fabio Carmona ◽  
Ravi R. Thiagarajan ◽  
Lauren Westgate ◽  
Michael A. Ferguson ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Kidney Injury

SP736EARLY SIGNS OF ACUTE KIDNEY INJURY IN CHILDREN WITH CONGENITAL HEART DISEASE

2016 ◽  
Vol 31 (suppl_1) ◽  
pp. i340-i340
Author(s):  
Anna Musielak ◽  
Magdalena Silska-Dittmar ◽  
Anna Benedyk ◽  
Danuta Ostalska-Nowicka ◽  
Jacek Zachwieja
Keyword(s):  
Acute Kidney Injury ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Kidney Injury

Acute Kidney Injury and Fluid Overload in Neonates Following Surgery for Congenital Heart Disease

2015 ◽  
Vol 6 (3) ◽  
pp. 401-406 ◽  
Author(s):  
Kurt D. Piggott ◽  
Meshal Soni ◽  
William M. Decampli ◽  
Jorge A. Ramirez ◽  
Dianna Holbein ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Fluid Overload ◽  
Kidney Injury
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