Single versus en bloc kidney transplant from donors less than or equal to 15 kg to pediatric recipients

2020 ◽  
Author(s):  
Hyejin Mo ◽  
Hyunmin Ko ◽  
Chris Tae Young Chung ◽  
Hyo Kee Kim ◽  
Ahram Han ◽  
...  
2012 ◽  
Vol 16 (2) ◽  
pp. 183-186 ◽  
Author(s):  
Mickael Afanetti ◽  
Patrick Niaudet ◽  
Olivier Niel ◽  
Marie Saint Faust ◽  
Pierre Cochat ◽  
...  

Author(s):  
Amit Sharma ◽  
Brianna Ruch ◽  
Yahya Alwatari ◽  
Ankur Gupta ◽  
Francisco Albuquerque ◽  
...  

2019 ◽  
Vol 11 (3) ◽  
pp. 128
Author(s):  
Navdeep Singh ◽  
ElmahdiA Elkhammas ◽  
Amer Rajab
Keyword(s):  

2001 ◽  
Vol 33 (1-2) ◽  
pp. 2034-2037 ◽  
Author(s):  
G Varela-Fascinetto ◽  
E Bracho ◽  
R Dávila ◽  
R Valdés ◽  
B Romero ◽  
...  

2020 ◽  
Vol 18 (7) ◽  
pp. 834-837
Author(s):  
Kwangho Yang ◽  
Dongil Kim ◽  
Soohong Kim ◽  
Hyojung Ko ◽  
Jaeryong Shim ◽  
...  

2016 ◽  
Vol 0 (0) ◽  
pp. 0
Author(s):  
Vikas Jain ◽  
Saurabh Jain ◽  
Paras Singhal ◽  
SumanLata Nayak ◽  
RajendraP Mathur

2021 ◽  
Vol 9 ◽  
Author(s):  
Malek Al Barbandi ◽  
Marissa J. Defreitas ◽  
Juan C. Infante ◽  
Mahmoud Morsi ◽  
Patricia A. Arroyo Parejo Drayer ◽  
...  

Introduction: The diagnosis of a post–surgical uroenteric fistula can be challenging and may be delayed for months after symptoms begin. A normal anion gap metabolic acidosis has been reported in up to 100% of patients after ureterosigmoidostomy, and bladder substitution using small bowel and/or colonic segments. Here, we describe a rare case of a pediatric patient who developed a uroenteric fistula from the transplant ureters into the small bowel, after an en-bloc kidney transplantation resulting in profound acidosis and deceptive watery diarrhea.Case Presentation: The patient is an 8-year-old girl with end stage kidney disease (ESKD) secondary to focal segmental glomerulosclerosis. Through a right retroperitoneal approach, she underwent a right native nephrectomy and a pediatric deceased donor en-bloc kidney transplant including two separate ureters. One month later, she had a renal allograft biopsy for suspected rejection. During the week after the biopsy, she experienced abdominal pain followed by watery diarrhea and metabolic acidosis requiring continuous bicarbonate/acetate infusions. An extensive gastro-intestinal evaluation for the cause of the diarrhea including endoscopy was inconclusive. The urine output decreased to <500 ml daily; although, the kidney function remained normal. After 2 weeks of unexplained watery diarrhea a magnetic resonance urogram with contrast was performed which demonstrated extravasation of urine from both ureters with fistulization into the small bowel. She underwent corrective surgery which identified the fistulous tract, which was resected and both ureters were re-implanted. The diarrhea and acidosis resolved, and she has maintained normal renal allograft function for over 1 year.Conclusion: An important aspect in the early diagnosis of a uroenteric fistula is the sudden onset of severe hyperchloremic metabolic acidosis that results when urine is diverted into the intestinal tract. The mechanism is similar to that described in cases of urinary diversions and/or bladder augmentation using the intestine. Important diagnostic tools are the measurements of solute excretion and pH in the urine as compared to the “watery diarrhea” or bowel output.Summary: We describe a case of a uroenteric fistula in a pediatric-en-bloc kidney transplant patient that went undiagnosed for almost 3 weeks due to the deceptive nature of the watery diarrhea which was actually urine. A uroenteric fistula should be considered in the differential diagnosis of diarrhea and hyperchloremic metabolic acidosis as a complication of kidney transplant. The simultaneous comparison of stool and urine pH and solute excretions may lead to the diagnosis, appropriate imaging and surgical intervention.


2021 ◽  
Vol 12 ◽  
Author(s):  
Jiawei Peng ◽  
Helong Dai ◽  
Hedong Zhang ◽  
Shaojie Yu ◽  
Xubiao Xie ◽  
...  

BackgroundKidney transplantation from donors who weigh ≤5 kg is performed at only a few transplant centers owing to the high complication and low graft survival rates associated with this approach.MethodsWe retrospectively compared the results of kidney transplantation at our center between January 2015 and December 2019 based on the following pediatric donor criteria: donor body weight ≤5 kg (n=32), 5 kg< donor weight ≤20 kg (n=143), and donor weight >20 kg (n=110). We also perform subgroup analysis of kidney transplantation outcomes from ≤5 kg donors, using conventional (dual separate and classic en-bloc KTx)/novel (en-bloc KTx with outflow tract) surgical methods and allocating to adult/pediatric recipients.ResultsThe death-censored graft survival rates from extremely low body weight ≤5kg at 1 month, and 1, 3, and 5 years were 90.6%, 80.9%, 77.5%, and 73.9%, respectively, which were significantly lower than that from larger body weight pediatric donors. However, the 3-, and 5-year post-transplantation eGFRs were not significantly different between the pediatric and adult recipient group. The thrombosis (18.8%) and urinary leakage (18.8%) rates were significantly higher in the donor weight ≤5 kg group. Compared with 5 kg< donor weight ≤20 kg group, donor weight ≤5kg group was at elevated risk of graft loss due to thrombosis (OR: 13.4) and acute rejection (OR: 6.7). No significant difference on the outcomes of extremely low body weight donor kidney transplantation was observed between adults and pediatric recipients. Urinary leakage rate is significantly lower in the novel operation (8.7%) than in the conventional operation group (44.4%).ConclusionsAlthough the outcomes of donor body weight ≤5kg kidney transplantation is inferior to that from donors with large body weight, it can be improved through technical improvement. Donors with body weight ≤5 kg can be considered as an useful source to expand the donor pool.


2014 ◽  
Vol 97 (5) ◽  
pp. 555-558 ◽  
Author(s):  
Wen-Yu Zhao ◽  
Lei Zhang ◽  
You-Hua Zhu ◽  
Yu Chen ◽  
Fan-Yuan Zhu ◽  
...  
Keyword(s):  
En Bloc ◽  

2008 ◽  
Vol 8 (12) ◽  
pp. 2600-2606 ◽  
Author(s):  
D. L. Gillen ◽  
C. O. Stehman-Breen ◽  
J. M. Smith ◽  
R. A. McDonald ◽  
B. A. Warady ◽  
...  

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