Living donor liver transplantation for inborn errors of metabolism - An underutilized resource in the United States

2016 ◽  
Vol 20 (6) ◽  
pp. 770-773 ◽  
Author(s):  
Thomas A. Pham ◽  
Gregory M. Enns ◽  
Carlos O. Esquivel
Keyword(s):  
United States ◽  
Liver Transplantation ◽  
Living Donor ◽  
Inborn Errors Of Metabolism ◽  
Living Donor Liver Transplantation ◽  
The United States ◽  
Donor Liver ◽  
Inborn Errors ◽  
Donor Liver Transplantation

Impact of Advanced Renal Dysfunction on Posttransplant Outcomes After Living Donor Liver Transplantation in the United States

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Therese Bittermann ◽  
Peter L. Abt ◽  
Kim M. Olthoff ◽  
Navpreet Kaur ◽  
Julie K. Heimbach ◽  
...  
Keyword(s):  
United States ◽  
Liver Transplantation ◽  
Renal Dysfunction ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
The United States ◽  
Donor Liver ◽  
Donor Liver Transplantation

Adult-to-Adult Living Donor Liver Transplantation: History, Current Practice, and Implications for the Future

2005 ◽  
Vol 15 (1) ◽  
pp. 36-44
Author(s):  
Claire Curran
Keyword(s):  
Liver Transplantation ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
The United States ◽  
Hepatitis C Infection ◽  
Donor Liver ◽  
Excessive Pressure ◽  
Donor Liver Transplantation ◽  
Number Of Patients ◽  
End Stage

More than 1600 Americans have received adult-to-adult living donor liver transplants. As the number of patients with end-stage liver disease is expected to grow significantly in the next 20 years due to hepatitis C infection, living donor liver transplantation has become a promising solution to the shortage of donor organs. The use of living donors provides organs in an environment of scarcity, allows patients to receive transplants when medically optimized, and produces liver segments with minimal ischemic damage. The donor complications most frequently cited in the medical literature include bile leaks and strictures, biloma, hepatic encephalopathy, wound infection, and pressure sores. In the wake of 2 donor deaths in the United States and subsequent media publicity, there have been new efforts by the transplant community to describe the risks and outcomes for donors, and establish safeguards to protect them from excessive pressure to donate.

Current Status of Living Donor Liver Transplantation in the United States

2019 ◽  
Vol 70 (1) ◽  
pp. 225-238 ◽  
Author(s):  
Samir Abu-Gazala ◽  
Kim M. Olthoff
Keyword(s):  
Liver Transplantation ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Deceased Donor ◽  
The United States ◽  
Current Status ◽  
Wait List ◽  
Donor Liver ◽  
Term Survival ◽  
Donor Liver Transplantation

Adult-to-adult living donor liver transplantation (LDLT) was introduced in response to the shortage of deceased donor liver grafts. The number of adult living donor transplants is increasing due to improved outcomes and increasing need. Advantages of LDLT include optimization of the timing of transplant, better organ quality, and lower rates of recipient mortality compared to staying on the wait list for deceased donor liver transplant. Donor safety remains the major focus when considering LDLT. Recent advancements have supported the increased use of LDLT to help decrease wait list death and improve long-term survival of transplant recipients.

Adult-to-Adult Living-Donor Liver Transplantation

Swiss Surgery ◽  
2003 ◽  
Vol 9 (5) ◽  
pp. 227-236 ◽  
Author(s):  
Majno ◽  
Mentha ◽  
Berney ◽  
Bühler ◽  
Giostra ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Therapeutic Option ◽  
Donor Liver ◽  
Donor Liver Transplantation ◽  
Multidisciplinary Program ◽  
First Case ◽  
Living Donor Transplantation ◽  
The Right

Living donor liver transplantation is a relatively new procedure in which the right side of the liver is harvested in a healthy donor and transplanted into a recipient. After the first case in 1994, over 3000 cases have been done worldwide. This review summarizes the reasons why the procedure is needed, describes its main technical aspects, highlights the boundaries in which it can be done safely, summarizes the current experience worldwide and describes the main points of the program in our unit. We argue that living-donor transplantation is a viable alternative to a long time on the waiting list for several patients, and it can be performed safely and successfully provided that all precautions are undertaken to minimize the risks in the donor and to increase the chances of a good outcome in the recipients. If these prerequisites are met, and within the framework of a structured multidisciplinary program, we believe that living-donor liver transplantation should be funded by health insurances as a recognized therapeutic option.

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