scholarly journals Glycemic Outcomes of Children 2‐6 Years of Age with Type 1 Diabetes during the Pediatric MiniMed ™ 670G System Trial

2022 ◽  
Author(s):  
Gregory P. Forlenza ◽  
Laya Ekhlaspour ◽  
Linda A. DiMeglio ◽  
Larry A. Fox ◽  
Henry Rodriguez ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Glycemic Outcomes

711-P: Glycemic Outcomes for Adult Type 1 Diabetes (T1D) with and without DKA Treated with an Electronic Glycemic Management System

Diabetes ◽  
2021 ◽  
Vol 70 (Supplement 1) ◽  
pp. 711-P
Author(s):  
JORDAN MESSLER ◽  
PRIYATHAMA VELLANKI ◽  
BRUCE W. BODE ◽  
ROBERT BOOTH ◽  
JOHN CLARKE
Keyword(s):  
Type 1 Diabetes ◽  
Management System ◽  
Adult Type ◽  
Glycemic Outcomes ◽  
Glycemic Management

scholarly journals Screening and Treatment Outcomes in Adults and Children with Type 1 Diabetes and Asymptomatic Celiac Disease: The CD-DIET Study

2020 ◽  
Author(s):  
Farid H. Mahmud ◽  
Antoine B.M. Clarke ◽  
Kariym C. Joachim ◽  
Esther Assor ◽  
Charlotte McDonald ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Celiac Disease ◽  
Glucose Monitoring ◽  
Gluten Free ◽  
Asymptomatic Patients ◽  
Adults And Children ◽  
Diet Study ◽  
Glycemic Outcomes ◽  
Design And Methods

<b>Objective</b>: To describe Celiac Disease (CD) screening rates and glycemic outcomes of a gluten-free diet (GFD) in type 1 diabetes patients asymptomatic for CD. <p><b>Research Design and Methods</b>: Asymptomatic patients (8-45 years) were screened for CD. Biopsy-confirmed CD participants were randomized to GFD or gluten-containing diet (GCD) to assess changes in HbA1c and continuous glucose monitoring (CGM) over 12 months. </p> <p><b>Results</b>: Adults had higher CD-seropositivity rates than children (6.8%, 95%CI 4.9% to 8.2%, N=1298 vs. 4.7%; 95%CI 3.4% to 5.9%, N=1089, p=0.035) with lower rates of prior CD-screening (6.9% vs 44.2%, p<0.0001). 51 participants were randomized to a GFD (N=27) or GCD (N=24). No HbA1c differences were seen between groups (+0.14%, 1.5mmol/mol; 95%CI: -0.79 to 1.08; p=0.76) although greater post-prandial glucose increases (4-hr +1.5mmol/L; 95%CI: 0.4 to 2.7; p=0.014) emerged with a GFD.</p> <p><b>Conclusions</b>: CD is frequently observed in asymptomatic patients with type 1 diabetes and clinical vigilance is warranted with initiation of a GFD. </p>

scholarly journals Glycemic Outcomes of Use of CLC Versus PLGS in Type 1 Diabetes: A Randomized Controlled Trial

Diabetes Care ◽  
2020 ◽  
Vol 43 (8) ◽  
pp. 1822-1828 ◽  
Author(s):  
Sue A. Brown ◽  
Roy W. Beck ◽  
Dan Raghinaru ◽  
Bruce A. Buckingham ◽  
Lori M. Laffel ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Type 1 Diabetes ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Glycemic Outcomes

scholarly journals Comment on Leelarathna et al. Duration of Hybrid Closed-Loop Insulin Therapy to Achieve Representative Glycemic Outcomes in Adults With Type 1 Diabetes. Diabetes Care 2020;43:e38–e39

Diabetes Care ◽  
2020 ◽  
Vol 43 (10) ◽  
pp. e167-e167
Author(s):  
Pierre Yves Benhamou ◽  
Stéphanie Madrolle ◽  
Sandrine Lablanche ◽  
Alexandre Gallegos ◽  
Yousra Tourki ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Insulin Therapy ◽  
Diabetes Care ◽  
Closed Loop ◽  
Glycemic Outcomes

scholarly journals A randomized clinical trial aimed at preventing poor psychosocial and glycemic outcomes in teens with type 1 diabetes (T1D)

2016 ◽  
Vol 49 ◽  
pp. 78-84 ◽  
Author(s):  
Jill Weissberg-Benchell ◽  
Joseph Rausch ◽  
Esti Iturralde ◽  
Aneta Jedraszko ◽  
Korey Hood
Keyword(s):  
Clinical Trial ◽  
Type 1 Diabetes ◽  
Randomized Clinical Trial ◽  
Glycemic Outcomes

1622-P: Glycemic Outcomes among Rural Patients in the Type 1 Diabetes Exchange Registry, January 2016 to March 2018

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 1622-P
Author(s):  
ARASHPREET K. GILL ◽  
MICHAEL D. GOTHARD ◽  
KATHALEEN BRIGGS EARLY
Keyword(s):  
Type 1 Diabetes ◽  
Glycemic Outcomes ◽  
Rural Patients

217-OR: Glycemic Outcomes by Ethnicity in Adults with Type 1 Diabetes Using Control-IQ Technology: Early Results from the CLIO Study

Diabetes ◽  
2021 ◽  
Vol 70 (Supplement 1) ◽  
pp. 217-OR
Author(s):  
STEPHANIE HABIF ◽  
HARSIMRAN SINGH ◽  
LARS MUELLER ◽  
MICHELLE L. MANNING ◽  
KIRSTIN N. WHITE ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Early Results ◽  
Glycemic Outcomes

Glycemic Outcomes of Use of CLC vs PLGS in Type 1 Diabetes: A Randomized, Controlled Trial

2020 ◽  
Author(s):  
Sue A. Brown ◽  
Roy W. Beck ◽  
Dan Raghinaru ◽  
Bruce A. Buckingham ◽  
Lori M. Laffel ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Controlled Trial ◽  
Limited Information ◽  
Loop Control ◽  
Measured Time ◽  
Device Use ◽  
Intent To Treat ◽  
Glycemic Outcomes ◽  
Age Range

<u>Background:</u> Limited information is available about glycemic outcomes with closed-loop control (CLC) compared with predictive-low glucose suspend (PLGS). <p><u>Methods:</u> After 6 months of use of a CLC system in a randomized trial, 109 participants with type 1 diabetes (age range 14 to 72 years, mean HbA1c 7.1% [54 mmol/mol]) were randomly assigned to CLC (N=54, Control-IQ) or PLGS (N=55, Basal-IQ) for 3 months. Primary outcome was CGM-measured time in range (TIR 70-180mg/dL). Baseline CGM metrics were computed from the last 3 months of the preceding study. <br> <u>Results</u>: All 109 participants completed the study. Mean±SD TIR was 71.1±11.2% at baseline and 67.6±12.6% using intent-to-treat analysis (69.1±12.2% using per-protocol analysis excluding periods of study-wide suspension of device use) over 13 weeks on CLC versus 70.0±13.6% and 60.4±17.1% on PLGS (difference = +5.9%, 95%CI +3.6 to +8.3; P<0.001]). Time >180mg/dL was lower in the CLC group than PLGS group (difference = -6.0%, 95%CI -8.4 to -3.7, p<0.001]) while time <54 mg/dL was similar (0.04%, 95% CI -0.05% to +0.13%; P=0.41). HbA1c after 13 weeks was lower on CLC than PLGS (7.2% [55 mmol/mol] versus 7.5% [56 mmol/mol], difference -0.34% [-3.7 mmol/mol], 95% CI -0.57 [-6.2 mmol/mol] to -0.11% [1.2 mmol/mol]; P=0.0035).<br> <u>Conclusion: </u>Following 6 months of CLC, switching to PLGS reduced TIR and increased HbA1c towards their pre-CLC values while hypoglycemia remained similarly reduced with both CLC and PLGS.</p>

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