The effect of coexisting autoimmune thyroiditis in children with Type 1 diabetes on optical coherence tomography results

2020 ◽  
Author(s):  
Marta Wysocka‐Mincewicz ◽  
Marta Baszyńska‐Wilk ◽  
Joanna Gołębiewska ◽  
Andrzej Olechowski ◽  
Aleksandra Byczyńska ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Type 1 Diabetes ◽  
Autoimmune Thyroiditis ◽  
Optical Coherence

Can optical coherence tomography predict early retinal microvascular pathology in type 1 diabetic adolescents without minimal diabetic retinopathy? A single-centre study

2015 ◽  
Vol 28 (1-2) ◽  
Author(s):  
Safinaz Adel Elhabashy ◽  
Nancy Samir Elbarbary ◽  
Karim Magdy Nageb ◽  
Mai Mostafa Mohammed
Keyword(s):  
Optical Coherence Tomography ◽  
Type 1 Diabetes ◽  
Diabetic Retinopathy ◽  
Ganglion Cell ◽  
Ganglion Cell Layer ◽  
Cell Layer ◽  
Retinal Thickness ◽  
Microvascular Complications ◽  
Optical Coherence

AbstractOptical coherence tomography (OCT) has been proven useful in measuring retinal thickness and volumes in patients with diabetes.To test whether OCT is able to identify early retinal changes and its potential correlations with metabolic parameters and other microvascular complications.Thirty patients with type 1 diabetes without minimal diabetic retinopathy (MDR) (17 males, 13 females, aged 14.3±2.4 years) compared with age-matched healthy volunteers were examined with OCT. Diabetes duration, anthropometric measurements, HbANo statistically significant differences were found between patients with (n=15) and without microvascular complications (n=15) compared to controls regarding retinal volume, nerve fibre layer volume (temporal and nasal quadrants) and ganglion cell layer area in both eyes. No correlation was found between the ganglion cell layer area and the clinical and laboratory characteristics of the patients, except a negative correlation with total serum cholesterol (Our study suggests that there is no advantage in performing OCT routinely in patients with type 1 diabetes mellitus without MDR. OCT did not show changes in retinal thickness in those patients compared to control. So OCT did not seem to be useful in the preclinical stages of diabetic retinopathy. Therefore, the conventional diagnostic methods are mandatory to detect early diabetic retinopathy.

scholarly journals Microperimetry and Optical Coherence Tomography Changes in Type-1 Diabetes Mellitus without Retinopathy

Diagnostics ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 136
Author(s):  
Elvira Orduna-Hospital ◽  
Judit Otero-Rodríguez ◽  
Lorena Perdices ◽  
Ana Sánchez-Cano ◽  
Ana Boned-Murillo ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Optical Coherence Tomography ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Negative Correlation ◽  
Retinal Sensitivity ◽  
Optical Coherence ◽  
Disease Evolution ◽  
Macular Sensitivity

Background: We aimed to measure and correlate inner retinal layer (IRL) thickness and macular sensitivity by optical coherence tomography (OCT) and by microperimetry, respectively, in type 1 diabetes mellitus patients (DM1) without diabetic retinopathy (DR). Methods: Fifty-one DM1 patients and 81 age-matched healthy subjects underwent measurement of the axial length (AL), retinal thickness in the macular ETDRS areas by swept source (SS)-OCT and macular sensitivity by microperimeter. Results: The total retinal and IRL thicknesses were thicker in the DM1 group (p < 0.05) in practically all ETDRS areas, and they had a generalized decrease in sensitivity (p < 0.05) in 9 areas between both groups. There was a significant negative correlation between retinal sensitivity and age in all areas and in visual acuity (VA) in 5 out of the 9 areas for DM1 patients. Only a mild negative correlation was observed between retinal sensitivity in the 5° nasal inner (5NI) area and in IRL thickness in the temporal inner (TI) area (−0.309 with p = 0.029) in the DM1 group. Conclusion: Aging and disease evolution in DM1 patients without DR signs generate a decrease in retinal sensitivity. There was a direct relationship between retinal sensitivity and macular thickness in the DM1 group.

scholarly journals Early microvascular retinal changes in optical coherence tomography angiography in patients with type 1 diabetes mellitus

2017 ◽  
Vol 95 (8) ◽  
pp. e751-e755 ◽  
Author(s):  
Joseph M. Simonett ◽  
Fabio Scarinci ◽  
Fabiana Picconi ◽  
Paola Giorno ◽  
Daniele De Geronimo ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Optical Coherence Tomography ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Optical Coherence Tomography Angiography ◽  
Optical Coherence
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