Inequalities in glycemic control in childhood onset type 2 diabetes in England and Wales—A national population‐based longitudinal study

2019 ◽  
Vol 20 (7) ◽  
pp. 821-831
Author(s):  
Amal R. Khanolkar ◽  
Rakesh Amin ◽  
David Taylor‐Robinson ◽  
Russell M. Viner ◽  
Justin Warner ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Longitudinal Study ◽  
Glycemic Control ◽  
Population Based ◽  
Childhood Onset ◽  
England And Wales ◽  
Onset Type ◽  
National Population

Ethnic Minorities Are at Greater Risk for Childhood-Onset Type 2 Diabetes and Poorer Glycemic Control in England and Wales

2016 ◽  
Vol 59 (3) ◽  
pp. 354-361 ◽  
Author(s):  
Amal R. Khanolkar ◽  
Rakesh Amin ◽  
David Taylor-Robinson ◽  
Russell Viner ◽  
Justin Warner ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Glycemic Control ◽  
Ethnic Minorities ◽  
Childhood Onset ◽  
England And Wales ◽  
Onset Type

scholarly journals Impact of type 2 diabetes and microvascular complications on mortality and cardiovascular outcomes in a multiethnic Asian population

2021 ◽  
Vol 9 (1) ◽  
pp. e001413
Author(s):  
Jonathan Yap ◽  
Kamalesh Anbalakan ◽  
Wan Ting Tay ◽  
Daniel Ting ◽  
Carol Yim Cheung ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Cardiovascular Disease ◽  
Glycemic Control ◽  
Microvascular Complications ◽  
Population Based ◽  
Cardiovascular Outcomes ◽  
Microvascular Complication ◽  
The Impact ◽  
Hba1c Levels

IntroductionDiabetes mellitus is a growing public health epidemic in Asia. We examined the impact of type 2 diabetes, glycemic control and microvascular complications on mortality and cardiovascular outcomes in a multiethnic population-based cohort of Asians without prior cardiovascular disease.Research design and methodsThis was a prospective population-based cohort study in Singapore comprising participants from the three major Asian ethnic groups: Chinese, Malays and Indians, with baseline examination in 2004–2011. Participants with type 1 diabetes and those with cardiovascular disease at baseline were excluded. Type 2 diabetes, Hemoglobin A1c (HbA1c) levels and presence of microvascular complications (diabetic retinopathy and nephropathy) were defined at baseline. The primary outcome was all-cause mortality and major adverse cardiovascular events (MACEs), defined as a composite of cardiovascular mortality, myocardial infarction, stroke and revascularization, collected using a national registry.ResultsA total of 8541 subjects were included, of which 1890 had type 2 diabetes at baseline. Subjects were followed for a median of 6.4 (IQR 4.8–8.8) years. Diabetes was a significant predictor of mortality (adjusted HR 1.74, 95% CI 1.45 to 2.08, p<0.001) and MACE (adjusted HR 1.64, 95% CI 1.39 to 1.93, p<0.001). In those with diabetes, higher HbA1c levels were associated with increased MACE rates (adjusted HR (per 1% increase) 1.18, 95% CI 1.11 to 1.26, p<0.001) but not mortality (p=0.115). Subjects with two microvascular complications had significantly higher mortality and MACE compared with those with only either microvascular complication (adjusted p<0.05) and no microvascular complication (adjusted p<0.05).ConclusionDiabetes is a significant predictor of mortality and cardiovascular morbidity in Asian patients without prior cardiovascular disease. Among patients with type 2 diabetes, poorer glycemic control was associated with increased MACE but not mortality rates. Greater burden of microvascular complications identified a subset of patients with poorer outcomes.

An Observational Longitudinal Study of the Impact of Sleeve Gastrectomy on Glycemic Control in Type 2 Diabetes Mellitus

2013 ◽  
Vol 15 (12) ◽  
pp. 990-995 ◽  
Author(s):  
Arundhati Dasgupta ◽  
Jasjeet Wasir ◽  
Maria Beloyartseva ◽  
Sandeep Malhotra ◽  
Ambrish Mithal
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Sleeve Gastrectomy ◽  
Longitudinal Study ◽  
Glycemic Control ◽  
The Impact

scholarly journals Glycemic control in youth‐onset type 2 diabetes correlates with weight loss

2020 ◽  
Vol 21 (7) ◽  
pp. 1116-1125
Author(s):  
Nancy Chang ◽  
Mei Yu Yeh ◽  
Jennifer K. Raymond ◽  
Mitchell E. Geffner ◽  
Ji Hoon Ryoo ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Weight Loss ◽  
Glycemic Control ◽  
Onset Type

scholarly journals Predictors of glycemic control among patients with Type 2 diabetes: A longitudinal study

2005 ◽  
Vol 5 (1) ◽  
Author(s):  
Stephen R Benoit ◽  
Regina Fleming ◽  
Athena Philis-Tsimikas ◽  
Ming Ji
Keyword(s):  
Type 2 Diabetes ◽  
Longitudinal Study ◽  
Glycemic Control

1321-P: Reduced Heart Rate Variability (HRV) in Young Adults with Youth-Onset Type 2 Diabetes (T2D) Is Related to Glycemic Control: The TODAY Study

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 1321-P
Author(s):  
AMY SANGHAVI SHAH ◽  
LAURE EL GHORMLI ◽  
FIDA BACHA ◽  
RYAN M. FARRELL ◽  
SAMUEL GIDDING ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Young Adults ◽  
Glycemic Control ◽  
Onset Type

Two Physical Activity Measures: Paffenbarger Physical Activity Questionnaire Versus Aerobics Center Longitudinal Study as Predictors of Adult-Onset Type 2 Diabetes in a Follow-Up Study

2017 ◽  
Vol 32 (4) ◽  
pp. 1070-1077 ◽  
Author(s):  
Serena Tonstad ◽  
Patti Herring ◽  
Jerry Lee ◽  
Jennifer Duxbury Johnson
Keyword(s):  
Physical Activity ◽  
Type 2 Diabetes ◽  
Longitudinal Study ◽  
Adult Onset ◽  
Physical Activity Questionnaire ◽  
Onset Type ◽  
Aerobics Center Longitudinal Study ◽  
Activity Questionnaire

Purpose: To compare 2 self-report methods of measuring weekly minutes of physical activity based on the Aerobics Center Longitudinal Study (ACLS) questionnaire and question 6 of the Paffenbarger Physical Activity Questionnaire (PPAQ) to determine the better predictor of adult-onset type 2 diabetes mellitus (T2DM). Design: An observational, prospective study. Setting: Survey data from the Adventist Health Study-2 (AHS-2) collected between 2002 and 2006 (baseline) and the Psychosocial Manifestations of Religion Sub-Study (PsyMRS), an AHS-2 subset collected 1 to 4 years later. Patients: Nine thousand eight hundred seventy-three male and female participants aged 23 to 106 years (mean, 63 years). Three hundred eighty participants reported adult-onset T2DM at follow-up. Measures: Question 6 from the PPAQ and a question adopted from the ACLS were assessed at baseline. Incident diabetes was defined as participants who reported receiving treatment for adult-onset T2DM in the last 12 months in the PsyMRS and not at baseline. Analysis: Multivariate logistic regression analyses controlled for age, gender, ethnicity, education, body mass index (BMI), diet, and sedentary activity. Each exposure variable was compared to nonexercisers. Results: The PPAQ (odds ratio [OR]: 0.998; 95% confidence interval [CI]: 0.997-1.000) and the ACLS (OR: 0.999; 95% CI: 0.998-1.001) exhibited similar likelihood of predicting incident adult-onset T2DM in a healthy, mixed-gender population when controlling for several confounders. Conclusions: The demonstrative nomenclature of the PPAQ may be more effectual in capturing physically active individuals than the ACLS notwithstanding generalizability and response bias limitations.

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