scholarly journals A survey of youth with new onset type 1 diabetes: Opportunities to reduce diabetic ketoacidosis

2016 ◽  
Vol 18 (7) ◽  
pp. 547-552 ◽  
Author(s):  
Luke Baldelli ◽  
Ben Flitter ◽  
Laura Pyle ◽  
David M. Maahs ◽  
Georgeanna Klingensmith ◽  
...  
2021 ◽  
pp. e00915
Author(s):  
Mostafa Alfishawy ◽  
Mahmoud Nassar ◽  
Mahmoud Mohamed ◽  
Moataz Fatthy ◽  
Riem El Messiery

PEDIATRICS ◽  
2021 ◽  
pp. e2021050856
Author(s):  
Clemens Kamrath ◽  
Joachim Rosenbauer ◽  
Alexander J. Eckert ◽  
Angeliki Pappa ◽  
Felix Reschke ◽  
...  

Author(s):  
Shelby Graf ◽  
Rachel Stork Poeppelman ◽  
Jennifer McVean ◽  
Arpana Rayannavar ◽  
Muna Sunni

Abstract Objectives To describe an atypical presentation of primary adrenal insufficiency in conjunction with new onset type 1 diabetes. Case presentation Here, we describe a case of new-onset type 1 diabetes (T1D) presenting simultaneously with an unusual presentation of primary adrenal insufficiency in a previously healthy 16-year-old. He was admitted for a typical presentation of diabetic ketoacidosis, but with extreme hyponatremia. An extensive workup revealed a low aldosterone level, appropriate cortisol level, and positive 21-hydroxylase antibodies. While the phenomenon of multiple autoimmune conditions developing in the same patient is well-described, this particular case has several atypical aspects. Our patient’s case highlights the danger of relying on random serum cortisol in the setting of acute illness to rule out adrenal insufficiency. Conclusions Adrenal insufficiency can present as isolated hypoaldosteronism without hypocortisolemia and can manifest as severe hyponatremia in the context of diabetic ketoacidosis. Workup for an unusual presentation of T1D should include a 21-hydroxylase antibody, as well as thyroid and celiac disease studies.


2016 ◽  
Vol 18 (7) ◽  
pp. 553-558 ◽  
Author(s):  
Eleanor R. Gunn ◽  
Benjamin B. Albert ◽  
Paul L. Hofman ◽  
Wayne S. Cutfield ◽  
Alistair J. Gunn ◽  
...  

2020 ◽  
Vol 11 (12) ◽  
pp. 426-428
Author(s):  
Baninder Kaur Baidwan ◽  
Elizabeth T. Walsh ◽  
Joseph A. Skelton ◽  
Cathrine Constantacos ◽  
Janel D. Hunter ◽  
...  

Author(s):  
Kokoro Sada ◽  
Shuji Hidaka ◽  
Makoto Takemaru ◽  
Daisuke Ueno ◽  
Hirotaka Shibata

Author(s):  
Judy L. Mintz ◽  
Morghan B. Jameson ◽  
Leah Akinseye ◽  
Evan A. Los

Abstract Objectives Report a novel case of new-onset type 1 diabetes in a pediatric patient presenting with DKA and concurrent Streptococcus intermedius brain abscess. Case presentation The following case report is that of a previously healthy 12 year-old girl presenting with new-onset type 1 diabetes with mild diabetic ketoacidosis and subsequently found to have a brain abscess. Over the course of her hospital stay, she developed seizures and was found to have a 1.3 × 1.0 × 1.2 cm right frontal parasagittal mass culture-positive for S. intermedius. Neurologic symptoms were unmasked once insulin treatment was initiated and ketosis improved, supporting the relationship between therapeutic ketosis and the management of medication-refractory epilepsy. Conclusions This case both supports the relationship between therapeutic ketosis and the management of medication-refractory epilepsy and highlights the need to carefully consider comorbid conditions in patients with DKA and new onset neurological symptoms.


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