The Scylla and Charybdis of glucose control in childhood type 1 diabetes?

2015 ◽  
Vol 16 (4) ◽  
pp. 235-241 ◽  
Author(s):  
Alison D McNeilly ◽  
Rory J McCrimmon
Keyword(s):  
Type 1 Diabetes ◽  
Glucose Control ◽  
Childhood Type 1 Diabetes ◽  
Childhood Type

Abstract #288 Dyslipidemia in Childhood Type 1 Diabetes in India: Prevalence Correlates and Management Challenges in a Resource Limited Setting

2019 ◽  
Vol 25 ◽  
pp. 117
Author(s):  
S Chandraprabha ◽  
T Jayalakshmi ◽  
Reshma Vijay ◽  
Kavitha Muniraj ◽  
Muralidhara Krishna ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Resource Limited Setting ◽  
Resource Limited ◽  
Childhood Type 1 Diabetes ◽  
Childhood Type ◽  
Limited Setting

Type 1 Diabetes-related Autoantibodies in Different Forms of Diabetes

2019 ◽  
Vol 15 (3) ◽  
pp. 199-204 ◽  
Author(s):  
Elin Pettersen Sørgjerd
Keyword(s):  
Type 2 Diabetes ◽  
Type 1 Diabetes ◽  
Autoimmune Diabetes ◽  
Acid Decarboxylase ◽  
Adult Onset ◽  
Latent Autoimmune Diabetes ◽  
Childhood Type 1 Diabetes ◽  
Childhood Type

Autoantibodies against Glutamic Acid Decarboxylase (GADA), insulinoma antigen-2 (IA- 2A), insulin (IAA) and the most recently Zinc Transporter 8 (ZnT8A) are one of the most reliable biomarkers for autoimmune diabetes in both children and adults. They are today the only biomarkers that can distinguish Latent Autoimmune Diabetes in Adults (LADA) from phenotypically type 2 diabetes. As the frequency of autoantibodies at diagnosis in childhood type 1 diabetes depends on age, GADA is by far the most common in adult onset autoimmune diabetes, especially LADA. Being multiple autoantibody positive have also shown to be more common in childhood diabetes compared to adult onset diabetes, and multiple autoantibody positivity have a high predictive value of childhood type 1 diabetes. Autoantibodies have shown inconsistent results to predict diabetes in adults. Levels of autoantibodies are reported to cause heterogeneity in LADA. Reports indicate that individuals with high levels of autoantibodies have a more type 1 diabetes like phenotype and individuals with low levels of autoantibody positivity have a more type 2 diabetes like phenotype. It is also well known that autoantibody levels can fluctuate and transient autoantibody positivity in adult onset autoimmune diabetes have been reported to affect the phenotype.

scholarly journals Incidence of childhood type 1 diabetes mellitus in Yamanashi Prefecture, Japan, 1986‐2018

2020 ◽  
Author(s):  
Tomohiro Saito ◽  
Koji Kobayashi ◽  
Kisho Kobayashi ◽  
Mie Mochizuki ◽  
Hideaki Yagasaki ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Childhood Type 1 Diabetes ◽  
Childhood Type

scholarly journals Next-Generation Sequencing Reveals ThatHLA-DRB3,-DRB4, and-DRB5May Be Associated With Islet Autoantibodies and Risk for Childhood Type 1 Diabetes

Diabetes ◽  
2016 ◽  
Vol 65 (3) ◽  
pp. 710-718 ◽  
Author(s):  
Lue Ping Zhao ◽  
Shehab Alshiekh ◽  
Michael Zhao ◽  
Annelie Carlsson ◽  
Helena Elding Larsson ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Next Generation Sequencing ◽  
Islet Autoantibodies ◽  
Next Generation ◽  
Childhood Type 1 Diabetes ◽  
Childhood Type ◽  
Generation Sequencing

Increasing incidence of childhood type 1 diabetes in Montenegro from 1997 to 2006

2010 ◽  
Vol 11 (6) ◽  
pp. 412-416 ◽  
Author(s):  
Mira Samardzic ◽  
Jelena Marinkovic ◽  
Nikola Kocev ◽  
Natasa Curovic ◽  
Natasa Terzic
Keyword(s):  
Type 1 Diabetes ◽  
Childhood Type 1 Diabetes ◽  
Childhood Type

scholarly journals Maturation of the humoral autoimmune response to epitopes of GAD in preclinical childhood type 1 diabetes

Diabetes ◽  
2000 ◽  
Vol 49 (2) ◽  
pp. 202-208 ◽  
Author(s):  
E. Bonifacio ◽  
V. Lampasona ◽  
L. Bernasconi ◽  
A. G. Ziegler
Keyword(s):  
Type 1 Diabetes ◽  
Autoimmune Response ◽  
Childhood Type 1 Diabetes ◽  
Childhood Type

Author response for " Worldwide differences in Childhood Type 1 Diabetes: The SWEET experience "

2020 ◽  
Author(s):  
Mahira Saiyed ◽  
Dhruvi Hasnani ◽  
G. Todd Alonso ◽  
Erick Richmond ◽  
Stéphane Besançon ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Author Response ◽  
Childhood Type 1 Diabetes ◽  
Childhood Type
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