Can ambulatory blood pressure monitoring detect early diastolic dysfunction in children with type 1 diabetes mellitus: correlations with B-type natriuretic peptide and tissue Doppler findings

2014 ◽  
Vol 17 (1) ◽  
pp. 21-27 ◽  
Author(s):  
Mustafa Kır ◽  
Benhur Cetin ◽  
Korcan Demir ◽  
Nuh Yılmaz ◽  
Ozgur Kızılca ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Type 1 Diabetes ◽  
Diastolic Dysfunction ◽  
Type 1 Diabetes Mellitus ◽  
Ambulatory Blood Pressure ◽  
Blood Pressure Monitoring ◽  
Tissue Doppler ◽  
Pressure Monitoring

scholarly journals Hyperfiltration, urinary albumin excretion, and ambulatory blood pressure in adolescents with Type 1 diabetes mellitus

2018 ◽  
Vol 314 (4) ◽  
pp. F667-F674 ◽  
Author(s):  
Julie A. Lovshin ◽  
Marko Škrtić ◽  
Petter Bjornstad ◽  
Rahim Moineddin ◽  
Denis Daneman ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Ambulatory Blood Pressure ◽  
Blood Pressure Monitoring ◽  
Urinary Albumin ◽  
Rapid Decline

Adolescents with Type 1 diabetes mellitus (T1DM) are at risk for hyperfiltration and elevated urinary albumin-to-creatinine ratio (ACR), which are early indicators of diabetic nephropathy. Adolescents with T1DM also develop early changes in blood pressure, cardiovascular structure, and function. Our aims were to define the relationships between hyperfiltration, ACR, and 24-h ambulatory blood pressure over time in adolescents with T1DM. Normotensive, normoalbuminuric adolescents ( n = 98) with T1DM underwent baseline and 2-yr 24-h ambulatory blood pressure monitoring, glomerular filtration rate (eGFR) estimated by cystatin C (Larsson equation), and ACR measurements. Linear regression models adjusted for diabetes duration, sex, and HbA1c were used to determine associations. Hyperfiltration (eGFR ≥ 133 ml/min) was present in 31% at baseline and 21% at 2-yr follow-up. Hyperfiltration was associated with greater odds of rapid GFR decline (>3 ml·min−1·yr−1) [OR: 5.33, 95%; CI: 1.87–15.17; P = 0.002] over 2 yr. Natural log of ACR at baseline was associated with greater odds of hyperfiltration (OR: 1.71, 95% CI: 1.00–2.92; P = 0.049) and 2-yr follow-up (OR: 2.14, 95%; CI: 1.09–4.19; P = 0.03). One SD increase in eGFR, but not ln ACR, at 2-yr follow-up conferred greater odds of nighttime nondipping pattern (OR: 1.96, 95% CI: 1.06–3.63; P = 0.03). Hyperfiltration was prevalent at baseline and at 2-yr follow-up, predicted rapid decline in GFR, and was related to ACR. Elevated GFR at 2-yr follow-up was associated with nighttime nondipping pattern. More work is needed to better understand early relationships between renal hemodynamic and systemic hemodynamic changes in adolescents with T1DM to reduce future cardiorenal complications.

Clinic blood pressure shows low sensitivity to detect alterations in ambulatory blood pressure monitoring in patients with type 1 diabetes

2014 ◽  
Author(s):  
Francisco Javier Vilchez-Lopez ◽  
Isabel Mateo-Gavira ◽  
Florentino Carral-San Laureano ◽  
Maria Victoria Garcia-Palacios ◽  
Jose Ortego-Rojo ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Type 1 Diabetes ◽  
Ambulatory Blood Pressure Monitoring ◽  
Ambulatory Blood Pressure ◽  
Blood Pressure Monitoring ◽  
Clinic Blood Pressure ◽  
Pressure Monitoring ◽  
Low Sensitivity

scholarly journals Daily blood pressure variations in patients with type 1 diabetes mellitus and nephropathy

2003 ◽  
Vol 49 (5) ◽  
pp. 5-10
Author(s):  
I. A. Bondar ◽  
V. V. Klimontov ◽  
Ye. A. Korolyova ◽  
L. I. Zheltova
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Type 1 Diabetes ◽  
Arterial Hypertension ◽  
Type 1 Diabetes Mellitus ◽  
Autonomic Dysfunction ◽  
Blood Pressure Monitoring ◽  
Inpatient Setting ◽  
Systemic Hemodynamic

То study a relationship between systemic hemodynamic parameters, albuminuria, and autonomic dysfunction in patients with type 1 diabetes mellitus (DM-1) without obvious nephropathy, the authors examined 55 patients in the inpatient setting. Twenty-nine patients had a normal urinary albumin excretion (CAE), 26 patients had microalbuminuria. 24-hour blood pressure monitoring (24-h BPM) was occillometrically made. The average daily, average diurnal and nocturnal values of systolic and diastolic blood pressure (BP) were significantly higher in DM-1 patients with microalbuniuria than in those with normal UAE. Routine autonomic cardiovascular tests showed that the incidence and severity of autonomic neuropathy were also higher in patients with microalbuminuria. Arterial hypertension (AH) diagnosed in compliance with the 24-h BPM criteria was detected. in 17.2%) of the DM-1 patients with normal UAE and in 42.3%) of the patients with microalbuminuria. According to the data of 24-h BPM, the incidence of arterial hypertension was 1.7 times as high as that evidenced by single BP measurements. The specific feature of circadian hemodynamic variations in patients with DM-1 was a low nocturnal BP decrease. 37.9%) of the patients with normoalbuminuria and 61.5%) of the patients with microalbuminuria had no normal (>10%)) nocturnal BP lowering. Stepwise regression analysis has ascertained that in patients with DM-1 without obvious nephropathy, systemic hemodynamic disorders are associated with albuminuria, autonomic dysfunction, and glycemic monitoring quality.

Alterations in ambulatory blood pressure monitoring are associated to proinflammatory cytokines in patients with type 1 diabetes

2014 ◽  
Author(s):  
Isabel Mateo-Gavira ◽  
Francisco Javier Vilchez-Lopez ◽  
Florentino Carral-San Laureano ◽  
Jose Ortego-Rojo ◽  
Francisco Manuel Visiedo-Garcia ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Type 1 Diabetes ◽  
Ambulatory Blood Pressure Monitoring ◽  
Proinflammatory Cytokines ◽  
Ambulatory Blood Pressure ◽  
Blood Pressure Monitoring ◽  
Pressure Monitoring

Usefulness of ambulatory blood pressure monitoring in pregnant women with type 1 diabetes

Diabetes Care ◽  
1999 ◽  
Vol 22 (9) ◽  
pp. 1507-1511 ◽  
Author(s):  
L. Flores ◽  
I. Levy ◽  
E. Aguilera ◽  
S. Martinez ◽  
R. Gomis ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Type 1 Diabetes ◽  
Pregnant Women ◽  
Ambulatory Blood Pressure Monitoring ◽  
Ambulatory Blood Pressure ◽  
Blood Pressure Monitoring ◽  
Pressure Monitoring

Evolution of ambulatory blood pressure monitoring in a cohort of patients with type 1 diabetes after 7 years

2014 ◽  
Author(s):  
Isabel Mateo-Gavira ◽  
Cristina Lopez-Tinoco ◽  
Francisco Javier Vilchez-Lopez ◽  
Jose Ortego-Rojo ◽  
Francisco Manuel Visiedo-Garcia ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Type 1 Diabetes ◽  
Ambulatory Blood Pressure Monitoring ◽  
Ambulatory Blood Pressure ◽  
Blood Pressure Monitoring ◽  
Pressure Monitoring
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