Diagnosis that clinicians don't think of, serum sickness‐like reaction

2021 ◽  
Author(s):  
Vildan Güngörer ◽  
Kübra Ertan ◽  
Şükrü Arslan
Keyword(s):  
Serum Sickness

scholarly journals Rituximab-induced serum-sickness in lymphoma: A case report

2021 ◽  
Author(s):  
B. Navarro-Matilla ◽  
A. Ramirez-Garcia ◽  
A. Sancho-Lopez ◽  
J.M. Mateos-Pérez ◽  
A. Plaza-Lopez ◽  
...  
Keyword(s):  
Case Report ◽  
Serum Sickness

Serum sickness reaction to obinutuzumab in a patient with chronic lymphocytic leukaemia

2021 ◽  
Vol 14 (12) ◽  
pp. e245557
Author(s):  
Oday Elmanaseer ◽  
Alzira R M Avelino ◽  
Amin Azem ◽  
Mihir Raval
Keyword(s):  
Chronic Lymphocytic Leukaemia ◽  
Effective Treatment ◽  
Inflammatory Markers ◽  
Lymphocytic Leukaemia ◽  
Maculopapular Rash ◽  
Serum Sickness ◽  
Rare Entity ◽  
Cd20 Antibody ◽  
Anti Cd20

Serum sickness (SS) is a known phenomenon; however, it is commonly missed due to vague symptoms, and is usually confounded by other aetiologies that present similarly. Obinutuzumab is a novel anti-CD20 antibody agent that has been approved for chronic lymphocytic leukaemia (CLL) treatment. At the time of approval, it was not linked to SS; however, this phenomenon has been recognised with other anti-CD20 agents like rituximab. SS remains a rare entity, but it is important to be recognised accurately and quickly in the appropriate circumstances, so that effective treatment with corticosteroids can be initiated to alleviate inflammatory symptoms. Here we present a patient with CLL who developed maculopapular rash, fever and polyarthritis and elevated inflammatory markers consistent with serum sickness triggered by obinutuzumab and was effectively treated with corticosteroids.

Serum Sickness in Guinea-Pigs

1965 ◽  
Vol 27 (3) ◽  
pp. 175-192 ◽  
Author(s):  
J.G. Feinberg ◽  
Janet M. Dewdney ◽  
Anne Temple
Keyword(s):  
Guinea Pigs ◽  
Serum Sickness

Human Serum Sickness

Medicine ◽  
1988 ◽  
Vol 67 (1) ◽  
pp. 40-57 ◽  
Author(s):  
LEONARD BIELORY ◽  
PEDRO GASCON ◽  
THOMAS J. LAWLEY ◽  
NEAL S. YOUNG ◽  
MICHAEL M. FRANK
Keyword(s):  
Human Serum ◽  
Serum Sickness

Minocycline-induced serum sickness-like reaction

2000 ◽  
Vol 14 (1) ◽  
pp. 67-68 ◽  
Author(s):  
Marina Landau ◽  
Eyal Shachar ◽  
Sarah Brenner
Keyword(s):  
Serum Sickness

scholarly journals Dažniausios vaistų sukeliamos alerginės reakcijos

2009 ◽  
Vol 6 (2) ◽  
Author(s):  
Brigita Budrytė ◽  
Brigita Šitkauskienė
Keyword(s):  
Serum Sickness ◽  
Drug Rash ◽  
Systemic Symptoms

Alergija vaistams, kitaip padidėjusio jautrumo reakcijos, sudaro maždaug 15 proc. visų šalutinių vaistų reakcijų. Dažniausiai jas sukelia antibiotikai, nesteroidiniai vaistai nuo uždegimo (NVNU), anestezijai vartojami vaistai, angiotenziną konvertuojančio fermento inhibitoriai (AKFI), beta adrenoblokatoriai, dekstranai, želatinos tirpalai, insulinas, heparinas, antiretrovirusiniai preparatai, jodo kontrastiniai preparatai. Alergiją vaistams gali skatinti tam tikri rizikos veiksniai: genetiniai, paciento amžius, lytis, organizmo imuniteto būklė, vaisto dozė, vartojimo būdas. Alergija vaistams pasireiškia įvairiai, gali būti pažeistos įvairios organizmo sistemos: oda, plaučiai, kepenys, inkstai, širdis ir kt. Dažniausiai alergija vaistams pasireiškia odos pažeidimu, kurio sunkiausia išraiška Stevens-Johnson, Lyell sindromai. Alergija vaistams gali pasireikšti ir sisteminėmis organizmo reakcijomis: anafilaksiniu šoku, padidėjusio jautrumo sindromu (DRESS sindromas, angl. drug rash with eosinophilia and systemic symptoms), į seruminę ligą panašiomis reakcijomis (SSLR, angl. Serum sickness-like reactions).

The Therapeutic Value of Calcium Salts in Serum Sickness

1936 ◽  
Vol 214 (4) ◽  
pp. 150-153 ◽  
Author(s):  
THEODORE J. CURPHEY ◽  
SAUL SOLOMON
Keyword(s):  
Serum Sickness ◽  
Calcium Salts ◽  
Therapeutic Value
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