Late-onset circulatory collapse of prematurity

2017 ◽  
Vol 59 (4) ◽  
pp. 391-396 ◽  
Author(s):  
Masahiko Kawai
2021 ◽  
Author(s):  
Chizuko Nakamura ◽  
Yukihide Miyosawa ◽  
Noriko Motoki ◽  
Toshimitsu Yanagisawa ◽  
Kanae Hirabayashi ◽  
...  

Author(s):  
Osamu Uemura ◽  
Kenji Ishikura ◽  
Tetsuji Kaneko ◽  
Daishi Hirano ◽  
Yuko Hamasaki ◽  
...  

Abstract Background Developmental programming of chronic kidney disease (CKD) in young adults is linked to preterm birth and intrauterine growth restriction (IUGR). Which confers a higher risk of progression to chronic kidney damage in children with very low birth weight (VLBW; born weighing < 1500 g): prematurity or IUGR? Methods This is a national historical cohort study of children with VLBW cared for in perinatal medical centers in Japan. Predictive factors included three latent variables (prematurity, IUGR, stress during neonatal period) and eight observed variables (gestational age, birth weight Z-score, maternal age, duration of treatment with antibiotics and diuretics, maternal smoking, late-onset circulatory collapse, kidney dysfunction) during the perinatal period. The primary endpoint was estimated glomerular filtration rate (eGFR) at age ≥ 3 years. A structural equation model was used to examine the pathologic constitution. Results The 446 children with VLBW included 253 boys and 193 girls, of mean age 5.8 ± 2.6 years and mean eGFR 111.7 ml/min/1.73 m2 at last encounter. Pathway analyses showed intrauterine malnutrition (β = 0.85) contributed more to chronic kidney damage than stress during the neonatal period (β = − 0.19) and prematurity (β = 0.12), and kidney dysfunction and late-onset circulatory collapse were important observed variables in stress during the neonatal period. Conclusions IUGR was more harmful to future kidneys of VLBW neonates. Neonatal kidney dysfunction and late-onset circulatory collapse were important risk factors for subsequent CKD development. This emphasizes the need for obstetricians to monitor for fetal growth restriction and neonatologists to minimize neonatal stress to prevent CKD in later life.


2019 ◽  
Vol 26 (1) ◽  
pp. 55-62
Author(s):  
Eun Sun Lee ◽  
Jin A Sohn ◽  
Han-Suk Kim ◽  
Ju Sun Heo ◽  
Jin A Lee

PEDIATRICS ◽  
1990 ◽  
Vol 85 (2) ◽  
pp. 165-171
Author(s):  
Simon R. M. Dobson ◽  
Carol J. Baker

Fifty-six neonates with enterococcal septicemia in a single hospital from 1977 through 1986 were studied. The incidence was low and constant until 1983, when an increase, attributable to infections in infants older than 7 days of age (late-onset), was noted. These infants were more premature (mean gestational age 29.5 vs 36.9 weeks) and had lower birth weights (mean 1250 vs 2700 g) than those with early-onset enterococcal sepsis, and in most the infections were characterized by a nosocomial origin. Infants with early-onset infection had a mild illness with respiratory distress typical of other etiologic agents or diarrhea without focal infection. By contrast, late-onset enterococcal sepsis was heralded by severe apnea, bradycardia, circulatory collapse, and increased ventilatory requirements. Focal infections, including scalp abscess or catheter-related infection (23% each), meningitis or pneumonia (15% each), were common. Rapid clinical improvement and clearance of bacteremia resulted from therapy with an aminoglycoside and either ampicillin or vancomycin, but only if abscesses were drained and intravascular catheters were removed. Mortality rates for early-onset, late-onset, and necrotizing entercolitis-associated infection were 6, 8, and 17%, respectively. Enterococcus is a frequent cause of late-onset septicemia in premature neonates, and empiric therapy should include appropriate antimicrobial agents.


PLoS ONE ◽  
2018 ◽  
Vol 13 (6) ◽  
pp. e0198518 ◽  
Author(s):  
Yume Suzuki ◽  
Yumi Kono ◽  
Takahiro Hayakawa ◽  
Hironori Shimozawa ◽  
Miyuki Matano ◽  
...  

2013 ◽  
Vol 24 (3) ◽  
pp. 148 ◽  
Author(s):  
Woon Ji Lee ◽  
Min Young Kim ◽  
Hye Jung Cho ◽  
Ji Sung Lee ◽  
Dong Woo Son

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