Vulvar aphthous ulcer after COVID‐19 vaccination

2021 ◽  
Author(s):  
Sabrina Popatia ◽  
Yvonne E. Chiu
Keyword(s):  
Aphthous Ulcer

Combined signatures of serum proteome and transcriptome in patients with recurrent aphthous ulcer

Oral Diseases ◽  
2021 ◽  
Author(s):  
Jie Bao ◽  
Juan Chen ◽  
XiZhao Zhang ◽  
Li Xu ◽  
YongSheng Fan ◽  
...  
Keyword(s):  
Aphthous Ulcer ◽  
Serum Proteome

scholarly journals Colchicine in the Treatment of Recurrent Oral Aphthous Ulcer -Open Clinical Trial in Bangladesh

1970 ◽  
Vol 39 (3) ◽  
Author(s):  
A Hassan ◽  
Z Ahmed ◽  
R Ali ◽  
F Ara ◽  
N Ahmed ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Oral Mucosa ◽  
Colchicine Treatment ◽  
Aphthous Ulcer ◽  
College Hospital ◽  
Medical College ◽  
Aphthous Ulceration ◽  
Benign Nature ◽  
Medical University

Background: Recurrent aphthous Ulceration (RAU) is characterized by necrotizing ulcers of the oral mucosa that persist, remit, and recur for variable periods of time. Despite the benign nature of the disease, RAU frequently affects quality of life as a result of long lasting and recurrent episodes of burning pain.Aim and objective: the aim of the study was to determine the efficacy of colchicine in treatment of recurrent oral aphthous ulcer.Methods: A clinical trial was conducted among 30 samples in the department of dermatology and venereology of Bangabandhu Sheikh Mujib Medical University and Dhaka Medical College Hospital, Dhaka. Study was performed among those who fulfilled the inclusion criteria. Data was collected from 1st September 2007 to 29th February. 2008 and enrolled data was analyzed by using statistical SPSS win 13.Results: Among 30 patients, 24 (80%) were male and 6(20%) were female. Mean age of the patients was 26.20 (±6.65) years. 26(87.7%) patients found ulcer in oral mucosa and 4(13.3%)in tongue, but previous family history was present in only 20% cases out of 30 patients. All patients experienced a marked decrease in symptoms during colchicine treatment in where; mean aphthae count was 3.27 (±1.05) before treatment and 0.43 (±0.68) during treatment. Pain score also reduced during treatment from 6.80 (±2.12) to 1.13 (±.1.11) which was statistically highly significant.Conclusions: Colchicine may be a promising modality of treatment in the therapeutic armamentarium for RAU.DOI: http://dx.doi.org/10.3329/bmj.v39i3.9948 BMJ 2010; 39(3)

scholarly journals Management of recurrent aphthous ulcer using corticosteroids, local anesthetics and nutritional supplements

2020 ◽  
Vol 16 (12) ◽  
pp. 992-998
Author(s):  
Manthra Prathoshini ◽  
Keyword(s):  
Local Anesthetics ◽  
Nutritional Supplements ◽  
Analysis Data ◽  
Aphthous Ulcer ◽  
P Value ◽  
Chi Square ◽  
Dental Patients ◽  
Recurrent Aphthous Ulcers ◽  
Chi Square Test ◽  
Topical Anaesthetics

Recurrent Aphthous ulcers are the most common oral lesions among dental patients. The ulcers, which usually occur on the nonkeratinized oral mucosa, can cause considerable pain and may interfere with eating, speaking, and swallowing. Therefore, it is of interest to report data on the management of recurrent aphthous ulcer using corticosteroids, local anesthetics and nutritional supplements. Case sheets of 76 patients who underwent treatment for recurrent aphthous ulcer between June 2019 and March 2020 at the Saveetha Dental College, India were used in this analysis. Data was analyzed using Chi square test at a P value < 0.05 that is statistically significant. Results show that topical anaesthetics in population (49%) were more effective that corticosteroids. Thus, topical anaesthetics are recommended for recurrent aphthous ulcer.

Development of Mucoadhesive Film-Forming Systems Containing Black Ginger Extract for Aphthous Ulcers

2021 ◽  
Vol 901 ◽  
pp. 104-110
Author(s):  
Nattanich Wattanaphraya ◽  
Somkamol Manchun ◽  
Siriporn Taokaew ◽  
Worawut Kriangkrai
Keyword(s):  
Film Formation ◽  
Aphthous Ulcer ◽  
Alternative Formulation ◽  
Ginger Extract ◽  
Inflammatory Agent ◽  
Mucoadhesive Polymers ◽  
Aphthous Ulcers ◽  
Film Forming ◽  
Gradual Release

Film-forming systems (FFSs) were developed by using Eudragit® E100 as a film former. Kaempferia parviflora (black ginger) extract was used as an anti-inflammatory agent for aphthous ulcers. The FFS could rapidly form a thin film in only 5 s when it was applied to a wet surface e.g. an aphthous ulcer. When the FFS was applied to a dry surface, the FFS without extract could form a film in 2-4 min. The incorporation of this extract contributed to delaying the film-formation time in the dry state; hence, the film-forming time increased to 6-8 min. The mucoadhesive property of FFSs was verified with the wash-off method. To simulate oromucosal conditions, the FFSs were applied on a cellophane membrane coated with mucin and washed by phosphate buffer of pH 6.8. The formulations without mucoadhesive polymers could not withstand flushing with a medium for more than 8 min without dislodging. Therefore, three different mucoadhesive agents were trialed: PVP K90, HPMC E15 LV, and HPC SL. The highest adhesion results were obtained when HPMC was added at 5%(w/w) as well as, the residence time was 22 min. In vitro release of black ginger extract from FFS showed a gradual release for 2 h. This study indicated that the FFS with HPMC E15 LV was an appropriate alternative formulation as a local delivery system for an aphthous ulcer.

Aphthous Ulcer

2007 ◽  
pp. 175-178
Author(s):  
Philip Buttaravoli
Keyword(s):  
Aphthous Ulcer
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