Palmoplantar keratoderma with curly hair

2017 ◽  
Vol 34 (6) ◽  
pp. 724-725
Author(s):  
Sanjay Singh ◽  
Prateek Sondhi ◽  
Gomathy Sethuraman
Keyword(s):  
Palmoplantar Keratoderma ◽  
Curly Hair

Palmoplantar keratoderma, curly hair and endomyocardial fibrodysplasia: A new syndrome

1988 ◽  
Vol 119 (s33) ◽  
pp. 13-14 ◽  
Author(s):  
J.N.W.N. Barker ◽  
N. Protonatorios ◽  
A. Tsatopoulou ◽  
D.M. MacDonald
Keyword(s):  
Palmoplantar Keratoderma ◽  
Curly Hair

scholarly journals 180 Mutations in FAM83G/PAWS1 cause autosomal recessive palmoplantar keratoderma with leukonychia and abundant curly hair

2016 ◽  
Vol 136 (9) ◽  
pp. S191 ◽  
Author(s):  
T. Maruthappu ◽  
L. McGinty ◽  
D. Blaydon ◽  
R. Duit ◽  
A. Maatta ◽  
...  
Keyword(s):  
Autosomal Recessive ◽  
Palmoplantar Keratoderma ◽  
Curly Hair

A Case of Aquagenic Palmoplantar Keratoderma.

2002 ◽  
Vol 64 (6) ◽  
pp. 693-697 ◽  
Author(s):  
Satoshi FUKUSHIMA ◽  
Mika KINOSHITA ◽  
Junko HIGO ◽  
Masato KIDOU ◽  
Fukiko AMANO ◽  
...  
Keyword(s):  
Palmoplantar Keratoderma

A Case of Multiple Eccrine Syringofibroadenoma with Palmoplantar Keratoderma

2018 ◽  
Vol 80 (6) ◽  
pp. 522-525
Author(s):  
Seisho SATO ◽  
Takahito CHIBA ◽  
Hiromaro KIRYU ◽  
Masutaka FURUE
Keyword(s):  
Palmoplantar Keratoderma

Hereditary palmoplantar keratoderma (four cases in three generations)

2001 ◽  
Vol 40 (2) ◽  
pp. 130-132 ◽  
Author(s):  
Virendra N. Sehgal ◽  
Sunil Kumar ◽  
Shashi Narayan
Keyword(s):  
Palmoplantar Keratoderma ◽  
Three Generations

scholarly journals Drugs Associated With the Development of Palmoplantar Keratoderma: A Systematic Review

2021 ◽  
pp. 120347542110045
Author(s):  
Sara Mirali ◽  
Abrahim Abduelmula ◽  
Asfandyar Mufti ◽  
Muskaan Sachdeva ◽  
Jensen Yeung
Keyword(s):  
Systematic Review ◽  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitors ◽  
Complete Resolution ◽  
Kinase Inhibitors ◽  
Healthcare Providers ◽  
Latency Period ◽  
Braf Inhibitors ◽  
Palmoplantar Keratoderma ◽  
Drug Induced

Background Palmoplantar keratoderma (PPK) are a heterogenous group of hereditary and acquired disorders that are characterized by excessive epidermal thickening of the palms and/or soles. PPK has been described as a rare adverse event for some medications. The aim of this systematic review was to summarize outcomes in PPK associated with various medications. This data will assist dermatologists and other healthcare providers treating patients with drug-induced PPK. Methods EMBASE and MEDLINE databases were searched in accordance with PRISMA guidelines using the keyword “palmoplantar keratoderma.” 40 studies met the inclusion criteria. Results A total of 247 patients (mean age: 57.0 years) were included in the analysis. Among patients whose sex was reported, 60.3% ( n = 35/58) were male. PPK most frequently developed after treatment with BRAF inhibitors (73.7%, n = 182/247), BRAF inhibitors combined with MEK1/2 inhibitors (15.4%, n = 38/247), tyrosine kinase inhibitors (TKIs) (3.2%, n = 8/247), or chemotherapy (2.4%, n = 6/247). The mean latency period between initiation of the drug and onset of PPK was 7.6 months (range: 0.25-90 months). Improvement of PPK was reported in 24 cases, with 50% ( n = 12/24) achieving complete resolution and 50% ( n = 12/24) achieving partial resolution. All patients who achieved complete resolution stopped the suspected drug, with a mean resolution period of 2.4 months (range: 2 weeks-6 months). The most common treatments for PPK were keratolytic treatments ( n = 10) and topical corticosteroids ( n = 4). Conclusions PPK was most frequently associated with targeted kinase inhibitors, specifically BRAF, MEK1/2, and tyrosine kinase inhibitors.

Autosomal dominant diffuse nonepidermolytic palmoplantar keratoderma due to a recurrent mutation in aquaporin-5

2015 ◽  
Vol 174 (2) ◽  
pp. 430-432 ◽  
Author(s):  
A. Abdul-Wahab ◽  
T. Takeichi ◽  
L. Liu ◽  
D. Lomas ◽  
B. Hughes ◽  
...  
Keyword(s):  
Autosomal Dominant ◽  
Recurrent Mutation ◽  
Palmoplantar Keratoderma ◽  
Aquaporin 5
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