scholarly journals Excess incidence and risk factors for recurrent pneumonia in bipolar disorder

2018 ◽  
Vol 72 (5) ◽  
pp. 337-348 ◽  
Author(s):  
Min-Shan Li ◽  
Galen Chin-Lun Hung ◽  
Shu-Yu Yang ◽  
Chun-Hung Pan ◽  
Ya-Tang Liao ◽  
...  
Keyword(s):  
Risk Factors ◽  
Bipolar Disorder ◽  
Recurrent Pneumonia ◽  
Excess Incidence

scholarly journals What can we learn from offspring studies in bipolar disorder?

2016 ◽  
Vol 22 (3) ◽  
pp. 176-185 ◽  
Author(s):  
Josephine Loftus ◽  
Bruno Etain ◽  
Jan Scott
Keyword(s):  
Risk Factors ◽  
Bipolar Disorder ◽  
Early Intervention ◽  
High Risk ◽  
Secondary Prevention ◽  
Environmental Risk ◽  
Clinical Characteristics ◽  
Intervention Strategies ◽  
Prevention Programmes ◽  
Methodological Approaches

SummaryWe offer a contemporary review of studies of the offspring of parents with bipolar disorder and explore the clinical characteristics of these populations. We discuss how different methodological approaches may influence study findings and may explain some of the heterogeneity in the results reported. We also highlight some of the environmental risk factors that may increase the likelihood of transition from an ‘at-risk’ or high-risk state to bipolar disorder. Last, we briefly discuss the implications of study findings for early intervention strategies and comment on such issues as genetic counselling and primary and early secondary prevention programmes.

A Pilot Study of Antidepressant-Induced Mania in Pediatric Bipolar Disorder: Characteristics, Risk Factors, and the Serotonin Transporter Gene

2006 ◽  
Vol 60 (9) ◽  
pp. 1005-1012 ◽  
Author(s):  
Fiona M. Baumer ◽  
Meghan Howe ◽  
Kim Gallelli ◽  
Diana Iorgova Simeonova ◽  
Joachim Hallmayer ◽  
...  
Keyword(s):  
Risk Factors ◽  
Bipolar Disorder ◽  
Pilot Study ◽  
Serotonin Transporter ◽  
Serotonin Transporter Gene ◽  
Pediatric Bipolar Disorder ◽  
Transporter Gene

Clinical and Environmental Risk Factors for Bipolar Disorder

2018 ◽  
Vol 26 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Ciro Marangoni ◽  
Gianni L. Faedda ◽  
Ross J. Baldessarini
Keyword(s):  
Risk Factors ◽  
Bipolar Disorder ◽  
Environmental Risk ◽  
Environmental Risk Factors

Risk factors for suicide attempts in patients with bipolar disorder misdiagnosed with major depressive disorder: results from a national survey in China

2020 ◽  
Author(s):  
Lin Chen ◽  
Yu-Yu Xu ◽  
Jing-Ge Du ◽  
Li-Min Xin ◽  
Su-Li Wang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Bipolar Disorder ◽  
Suicidal Ideation ◽  
Clinical Characteristics ◽  
Suicide Attempts ◽  
Multiple Logistic Regression ◽  
Regression Analyses ◽  
Major Depressive ◽  
Suicide Attempters ◽  
Depressive Episodes

Abstract Background: Bipolar disorder (BD) is a kind of mental disorder with the greatest risk of suicide, but it is often misdiagnosed as major depressive disorder (MDD) clinically. This study aimed to analyze the sociodemographic factors and clinical characteristics associated with suicide attempts (SA) in patients with BD misdiagnosed with MDD in China. Methods: A total of 1487 MDD patients were consecutively enrolled in 13 mental health centers in China. Data on patients’ sociodemographic and clinical characteristics were collected using a standardized protocol. Of these, 306 BD patients were misdiagnosed with MDD according to the Mini International Neuropsychiatric Interview (MINI). Suicide attempters and non-attempters were classified by the suicidality module of the MINI. Multiple logistic regression analyses were performed to assess the association between the independent variables of interest and SA in BD patients misdiagnosed with MDD. Results: Of the 306 BD patients misdiagnosed with MDD, 225 (73.5%) were non-attempters and 81 (26.5%) were attempters. Compared to non-attempters, attempters were older (Z =2.2, p = 0.03) and had more admissions(χ2 =6.1, p = 0.013), more frequent depressive episodes, more atypical characteristics (e.g. increased appetite, weight gain, and more sleep time)(χ2 = 5.8, p = 0.016), more suicidal ideation (χ2 = 27.3, p < 0.001), more psychotic symptoms (χ2 = 7.4, p = 0.006) and more seasonal depressive episodes (χ2 = 5.6, p = 0.018). Multiple logistic regression analyses revealed that attempters were characterized by more suicidal ideation (OR = 5.7, 95% CI: 2.6–12.5) and frequent depressive episodes (OR = 2.4, 95% CI: 1.3–4.6). The limitations of this study include its cross-sectional design and data collection by suicide attempters’ retrospective recall. Conclusions: The findings of this study suggest that BD patients misdiagnosed with MDD are at a higher risk of suicide, and more frequent depressive episodes and suicidal ideation are risk factors for attempted suicide. Early identification of and interventions for these risk factors might reduce the risk of suicide in BD patients misdiagnosed with MDD.

Clinical phenotype and genetic risk factors for bipolar disorder with binge eating: an update

2019 ◽  
Vol 19 (9) ◽  
pp. 867-879 ◽  
Author(s):  
Alfredo B. Cuellar-Barboza ◽  
Stacey J. Winham ◽  
Joanna M. Biernacka ◽  
Mark A. Frye ◽  
Susan L. McElroy
Keyword(s):  
Risk Factors ◽  
Bipolar Disorder ◽  
Binge Eating ◽  
Genetic Risk ◽  
Clinical Phenotype ◽  
Genetic Risk Factors

scholarly journals Risk factors for suicide in bipolar disorder: A cohort study of 12,850 patients

2019 ◽  
Vol 29 ◽  
pp. S372-S373
Author(s):  
C. Hansson ◽  
E. Joas ◽  
E. Pålsson ◽  
K. Hawton ◽  
B. Runesson ◽  
...  
Keyword(s):  
Risk Factors ◽  
Bipolar Disorder ◽  
Cohort Study ◽  
Risk Factors For Suicide

scholarly journals Study of Risk Factors Associated with Suicide Attempt in Patients with Bipolar Disorder Type I

2020 ◽  
Vol 11 (02) ◽  
pp. 291-298
Author(s):  
Karthick Subramanian ◽  
Vikas Menon ◽  
Siddharth Sarkar ◽  
Vigneshvar Chandrasekaran ◽  
Nivedhitha Selvakumar
Keyword(s):  
Risk Factors ◽  
Bipolar Disorder ◽  
Logistic Regression ◽  
Family History ◽  
Suicide Attempt ◽  
Coping Strategies ◽  
Binary Logistic Regression ◽  
Type I ◽  
Factors Associated ◽  
History Of

Abstract Background Suicide is the leading contributor to mortality in bipolar disorder (BD). A history of suicidal attempt is a robust predictive marker for future suicide attempts. Personality profiles and coping strategies are the areas of contemporary research in bipolar suicides apart from clinical and demographic risk factors. However, similar research in developing countries is rarer. Objectives The present study aimed to identify the risk factors associated with suicidal attempts in BD type I (BD-I). Materials and Methods Patients with BD-I currently in clinical remission (N = 102) were recruited. Sociodemographic details and the clinical data were collected using a semistructured pro forma. The psychiatric diagnoses were confirmed using the Mini-International Neuropsychiatric Interview 5.0. The National Institute of Mental Health–Life Chart Methodology Clinician Retrospective Chart was used to chart the illness course. Presumptive Stressful Life Events Scale, Coping Strategies Inventory Short Form, Buss–Perry aggression questionnaire, Past Feelings and Acts of Violence, and Barratt Impulsivity scale were used to assess the patient’s stress scores, coping skills, aggression, violence, and impulsivity, respectively. Statistical Analysis Descriptive statistics were used for demographic details and characteristics of the illness course. Binary logistic regression analyses were performed to identify the predictors for lifetime suicide attempt in BD-I. Results A total of 102 patients (males = 49 and females = 53) with BD-I were included. Thirty-seven subjects (36.3%) had a history of suicide attempt. The illness course in suicide attempters more frequently had an index episode of depression, was encumbered with frequent mood episodes, especially in depression, and had a higher propensity for psychiatric comorbidities. On binary logistic regression analysis, the odds ratios (ORs) for predicting a suicide attempt were highest for positive family history of suicide (OR: 13.65, 95% confidence interval [CI]: 1.28–145.38, p = 0.030), followed by the presence of an index depressive episode (OR: 6.88, 95% CI: 1.70–27.91, p = 0.007), and lower scores on problem-focused disengagement (OR: 0.72, 95% CI: 0.56–0.92, p = 0.009). Conclusion BD-I patients with lifetime suicide attempt differ from non-attempters on various course-related and temperamental factors. However, an index episode depression, family history of suicide, and lower problem-focused engagement can predict lifetime suicide attempt in patients with BD-I.

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