scholarly journals Reliability, validity, and responsiveness of the Japanese version of International Restless Legs Syndrome Study Group rating scale for restless legs syndrome in a clinical trial setting

2013 ◽  
Vol 67 (6) ◽  
pp. 412-419 ◽  
Author(s):  
Yuichi Inoue ◽  
Yasunori Oka ◽  
Tatsuo Kagimura ◽  
Kenji Kuroda ◽  
Koichi Hirata
Keyword(s):  
Clinical Trial ◽  
Restless Legs Syndrome ◽  
Rating Scale ◽  
Japanese Version ◽  
Study Group ◽  
Clinical Trial Setting ◽  
Restless Legs ◽  
Group Rating ◽  
Trial Setting

The reliability, validity and responsiveness of the International Restless Legs Syndrome Study Group rating scale and subscales in a clinical-trial setting

2006 ◽  
Vol 7 (4) ◽  
pp. 340-349 ◽  
Author(s):  
Linda Abetz ◽  
Robert Arbuckle ◽  
Richard P. Allen ◽  
Diego Garcia-Borreguero ◽  
Wayne Hening ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Restless Legs Syndrome ◽  
Rating Scale ◽  
Study Group ◽  
Clinical Trial Setting ◽  
Restless Legs ◽  
Group Rating ◽  
Trial Setting

International Restless Legs Syndrome Study Group Rating Scale--Japanese Version

2013 ◽  
Author(s):  
Yuichi Inoue ◽  
Yasunori Oka ◽  
Tatsuo Kagimura ◽  
Kenji Kuroda ◽  
Koichi Hirata
Keyword(s):  
Restless Legs Syndrome ◽  
Rating Scale ◽  
Japanese Version ◽  
Study Group ◽  
Restless Legs ◽  
Group Rating

An item response analysis of the international restless legs syndrome study group rating scale for restless legs syndrome

2005 ◽  
Vol 6 (2) ◽  
pp. 131-139 ◽  
Author(s):  
Glen R. Wunderlich ◽  
Kenneth R. Evans ◽  
Terrence Sills ◽  
Stephane Pollentier ◽  
Juergen Reess ◽  
...  
Keyword(s):  
Item Response ◽  
Restless Legs Syndrome ◽  
Rating Scale ◽  
Response Analysis ◽  
Study Group ◽  
Restless Legs ◽  
Group Rating

International Restless Legs Syndrome Study Group Rating Scale

2011 ◽  
pp. 195-202
Author(s):  
Azmeh Shahid ◽  
Kate Wilkinson ◽  
Shai Marcu ◽  
Colin M. Shapiro
Keyword(s):  
Restless Legs Syndrome ◽  
Rating Scale ◽  
Study Group ◽  
Restless Legs ◽  
Group Rating

scholarly journals Association of Decreased Serum BDNF With Restless Legs Syndrome in Parkinson's Disease Patients

2021 ◽  
Vol 12 ◽  
Author(s):  
Yi-xian Huang ◽  
Qi-lin Zhang ◽  
Cai-li Huang ◽  
Wen-qi Wu ◽  
Jia-wei Sun
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Restless Legs Syndrome ◽  
Rating Scale ◽  
Diagnostic Value ◽  
Study Group ◽  
Restless Legs ◽  
Blood Biomarker ◽  
Group Rating ◽  
Serum Bdnf

Objective: To objective of the study was to investigate whether serum brain-derived neurotrophic factor (BDNF) levels are associated with the severity of restless legs syndrome (RLS) in Parkinson's disease (PD).Methods: A total of 249 PD patients with (n = 53) and without RLS (n = 196) and 326 age-matched controls were included in this study. All the serum BDNF levels of the participants were measured. The International Restless Legs Syndrome Study Group Rating Scale (IRLSSG-RS) was administered for the severity of RLS. The severity of PD patients were assessed by the Unified PD Rating Scale (UPDRS) and the Hoehn and Yahr (H-Y) stage.Results: The prevalence of RLS was significantly higher in PD patients (21.3%) than in the controls group (7.4%) (p < 0.05). The IRLSSG-RS score in PD patients with RLS (16.25 ± 5.24) was significantly increased than in controls with RLS (12.08 ± 3.99) (p < 0.01). The serum BDNF levels were significantly decreased in PD patients with RLS than in PD patients without RLS, controls without RLS, and controls with RLS (p < 0.001). BDNF levels were negatively associated with IRLSSG-RS in both PD patients with RLS and controls with RLS group (both p < 0.01). Multiple regression analysis confirmed that in either PD with RLS or controls with RLS group, BDNF was an independent contributor to IRLSSG-RS (both p < 0.01).Conclusions: Decreased serum BDNF levels may be involved in the pathophysiology of RLS in PD, suggesting that it may serve as a potential blood biomarker of diagnostic value for RLS in PD.

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