Malignant melanoma with areas of rhabdomyosarcomatous differentiation arising in a giant congenital nevus with RAF1 gene fusion

2019 ◽  
Author(s):  
Aline Baltres ◽  
Aicha Salhi ◽  
Aurelie Houlier ◽  
Daniel Pissaloux ◽  
Franck Tirode ◽  
...  
Keyword(s):  
Malignant Melanoma ◽  
Gene Fusion ◽  
Congenital Nevus ◽  
Giant Congenital Nevus

scholarly journals Giant Congenital Nevus and Malignant Melanoma

1989 ◽  
Vol 92 (5) ◽  
pp. S310-S314 ◽  
Author(s):  
Yoshiaki Hori ◽  
Juichiro Nakayama ◽  
Mitsuse Okamoto ◽  
Shonosuke Nagae ◽  
Shunichiro Taniguchi ◽  
...  
Keyword(s):  
Malignant Melanoma ◽  
Congenital Nevus ◽  
Giant Congenital Nevus

Malignant Melanoma in Association With a Thymic Nevus in a Patient With a Giant Congenital Nevus

2017 ◽  
Vol 39 (7) ◽  
pp. 538-541 ◽  
Author(s):  
Yulia Shvartser-Beryozkin ◽  
Alexander Yakobson ◽  
Daniel Benharroch ◽  
Milton Saute ◽  
Meora Feinmesser
Keyword(s):  
Malignant Melanoma ◽  
Congenital Nevus ◽  
Giant Congenital Nevus

Giant Congenital Nevus and Malignant Melanoma.

1989 ◽  
Vol 92 (s5) ◽  
pp. 310S-314S ◽  
Author(s):  
Yoshiaki Hori ◽  
Juichiro Nakayama ◽  
Mitsuse Okamoto ◽  
Shonosuke Nagae ◽  
Shunichiro Taniguchi ◽  
...  
Keyword(s):  
Malignant Melanoma ◽  
Congenital Nevus ◽  
Giant Congenital Nevus

scholarly journals Transformation of Malignant Melanoma From Giant Nevus in Infantile Penis

2020 ◽  
Vol 7 ◽  
Author(s):  
Dong Hwan Lee ◽  
Min Ji Kim ◽  
Il Jae Lee ◽  
Dong Ha Park
Keyword(s):  
Malignant Melanoma ◽  
Lymphovascular Invasion ◽  
Radical Resection ◽  
Case Presentation ◽  
Congenital Nevus ◽  
Malignant Changes ◽  
Giant Nevus ◽  
Gross Examination ◽  
Giant Congenital Nevus

Background: Malignant melanoma is the most serious type of skin cancer, and its incidence rate increases with age. Malignant melanoma in infants has been rarely reported in the literature. Herein, we report a case of malignant transformation of a nodular lesion found in the penis of a patient with a giant congenital nevus.Case presentation: A 1-month-old male patient was admitted due to the presence of a giant congenital nevus involving the lower abdomen, bilateral inguinal areas, genitals, and left thigh and knee. Six months later, nodules measuring 1 cm in diameter protruding from the genital area were noted, and a part of the nodule was removed via elliptical excision with the patient under general anesthesia. Gross examination showed an edematous lesion similar to a neurofibroma and with unclear boundaries. Biopsy revealed a malignant melanoma, with a Breslow thickness of at least 3 mm, and absence of lymphovascular invasion; the biopsy confirmed incomplete excision. The patient was scheduled for radical resection, but reconstruction was not performed following surgical resection due to the guardian's refusal. Hence, the patient only received an adjuvant medical treatment and eventually died.Conclusion: We reported a rare case of an infant with a malignant melanoma in the penis. Congenital malignant melanoma rarely occurs in infants; however, due to its fatal consequences, follow-up should be performed to assess for malignant changes.

scholarly journals Congenital Giant Melanocytic Nevi

Rare Tumors ◽  
2009 ◽  
Vol 1 (1) ◽  
pp. 1-3 ◽  
Author(s):  
Ghulam S. Hashmi ◽  
Syed S. Ahmed ◽  
Shahla Khan
Keyword(s):  
Malignant Melanoma ◽  
Surgical Management ◽  
Skin Tumors ◽  
Unique Case ◽  
Congenital Nevus ◽  
Melanocytic Nevi ◽  
Early Removal ◽  
Common Skin ◽  
Giant Congenital Nevus

Nevi are common skin tumors caused by abnormal overgrowth of cells from the epidermal and dermal layers of the skin. Most nevi are benign, but some pre-cancerous nevi must be monitored or removed. The giant congenital nevus is greater than 10 cm in size, pigmented and often hairy. Between 4% and 6% of these lesions will develop into a malignant melanoma. Since approximately 50% of the melanoma develop by the age of two, and 80% by the age of seven, early removal is recommended. The objective of this paper is to present a unique case of giant nevi and their surgical management.

Sign in / Sign up

Export Citation Format

Share Document