scholarly journals Iris pigmentation as a quantitative trait: variation in populations of European, East Asian and South Asian ancestry and association with candidate gene polymorphisms

2015 ◽  
Vol 29 (2) ◽  
pp. 141-162 ◽  
Author(s):  
Melissa Edwards ◽  
David Cha ◽  
S. Krithika ◽  
Monique Johnson ◽  
Gillian Cook ◽  
...  
Keyword(s):  
Candidate Gene ◽  
South Asian ◽  
Quantitative Trait ◽  
Gene Polymorphisms ◽  
East Asian ◽  
Trait Variation ◽  
Asian Ancestry ◽  
Iris Pigmentation

scholarly journals A Genome-Wide Association Study of Skin and Iris Pigmentation among Individuals of South Asian Ancestry

2019 ◽  
Vol 11 (4) ◽  
pp. 1066-1076 ◽  
Author(s):  
Manjari Jonnalagadda ◽  
Muhammad Ashhad Faizan ◽  
Shantanu Ozarkar ◽  
Richa Ashma ◽  
Shaunak Kulkarni ◽  
...  
Keyword(s):  
Association Study ◽  
South Asian ◽  
Genome Wide Association Study ◽  
Genome Wide Association ◽  
Asian Ancestry ◽  
Genome Wide ◽  
A Genome ◽  
Iris Pigmentation

Thresholds for Small for Gestational Age Among Newborns of East Asian and South Asian Ancestry

2009 ◽  
Vol 31 (4) ◽  
pp. 322-330 ◽  
Author(s):  
Joel G. Ray ◽  
Depeng Jiang ◽  
Michael Sgro ◽  
Rajiv Shah ◽  
Gita Singh ◽  
...  
Keyword(s):  
South Asian ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
East Asian ◽  
Asian Ancestry

scholarly journals Birthweight Curves and Thresholds for Small for Gestational Age Tailored to Newborns of East Asian and South Asian Ancestry

2009 ◽  
Vol 14 (suppl_A) ◽  
pp. 37A-37A ◽  
Author(s):  
M Sgro ◽  
J Ray ◽  
D Jiang ◽  
R Shah ◽  
G Singh ◽  
...  
Keyword(s):  
South Asian ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
East Asian ◽  
Asian Ancestry

Cold Sweetening in Diploid Potato: Mapping Quantitative Trait Loci and Candidate Genes

Genetics ◽  
2002 ◽  
Vol 162 (3) ◽  
pp. 1423-1434
Author(s):  
Cristina M Menéndez ◽  
Enrique Ritter ◽  
Ralf Schäfer-Pregl ◽  
Birgit Walkemeier ◽  
Alexandra Kalde ◽  
...  
Keyword(s):  
Candidate Gene ◽  
Cold Storage ◽  
Quantitative Trait ◽  
Metabolic Pathways ◽  
Sugar Content ◽  
Candidate Gene Approach ◽  
Diploid Potato ◽  
Glucose Content ◽  
Gene Markers ◽  
Cold Sweetening

Abstract A candidate gene approach has been used as a first step to identify the molecular basis of quantitative trait variation in potato. Sugar content of tubers upon cold storage was the model trait chosen because the metabolic pathways involved in starch and sugar metabolism are well known and many of the genes have been cloned. Tubers of two F1 populations of diploid potato grown in six environments were evaluated for sugar content after cold storage. The populations were genotyped with RFLP, AFLP, and candidate gene markers. QTL analysis revealed that QTL for glucose, fructose, and sucrose content were located on all potato chromosomes. Most QTL for glucose content mapped to the same positions as QTL for fructose content. QTL explaining >10% of the variability for reducing sugars were located on linkage groups I, III, VII, VIII, IX, and XI. QTL consistent across populations and/or environments were identified. QTL were linked to genes encoding invertase, sucrose synthase 3, sucrose phosphate synthase, ADP-glucose pyrophosphorylase, sucrose transporter 1, and a putative sucrose sensor. The results suggest that allelic variants of enzymes operating in carbohydrate metabolic pathways contribute to the genetic variation in cold sweetening.

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