Systematic Review and Meta‐Analysis on Neuropsychological Effects of Long‐Term Use of Opioids in Patients With Chronic Noncancer Pain

Pain Practice ◽  
2018 ◽  
Author(s):  
Nicola Allegri ◽  
Simona Mennuni ◽  
Eliana Rulli ◽  
Nicola Vanacore ◽  
Oscar Corli ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Chronic Noncancer Pain ◽  
Neuropsychological Effects ◽  
Noncancer Pain

scholarly journals Outcomes Associated with Opioid Use in the Treatment of Chronic Noncancer Pain in Older Adults: A Systematic Review and Meta-Analysis

2010 ◽  
Vol 58 (7) ◽  
pp. 1353-1369 ◽  
Author(s):  
Maria Papaleontiou ◽  
Charles R. Henderson Jr ◽  
Barbara J. Turner ◽  
Alison A. Moore ◽  
Yelena Olkhovskaya ◽  
...  
Keyword(s):  
Systematic Review ◽  
Older Adults ◽  
Meta Analysis ◽  
Opioid Use ◽  
Chronic Noncancer Pain ◽  
Noncancer Pain

Interventions to Influence Opioid Prescribing Practices for Chronic Noncancer Pain: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 60 (1) ◽  
pp. e15-e26
Author(s):  
Michael Asamoah-Boaheng ◽  
Oluwatosin A. Badejo ◽  
Louise V. Bell ◽  
Norman Buckley ◽  
Jason W. Busse ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Prescribing Practices ◽  
Chronic Noncancer Pain ◽  
Opioid Prescribing ◽  
Noncancer Pain

How Can We Best Reduce Pain Catastrophizing in Adults With Chronic Noncancer Pain? A Systematic Review and Meta-Analysis

2018 ◽  
Vol 19 (3) ◽  
pp. 233-256 ◽  
Author(s):  
Robert Schütze ◽  
Clare Rees ◽  
Anne Smith ◽  
Helen Slater ◽  
Jared M. Campbell ◽  
...  
Keyword(s):  
Systematic Review ◽  
Pain Catastrophizing ◽  
Meta Analysis ◽  
Chronic Noncancer Pain ◽  
Noncancer Pain

scholarly journals Trigger Point Manual Therapy for the Treatment of Chronic Noncancer Pain in Adults: A Systematic Review and Meta-analysis

2019 ◽  
Vol 100 (3) ◽  
pp. 562-577 ◽  
Author(s):  
Diarmuid Denneny ◽  
Helena C. Frawley ◽  
Katrine Petersen ◽  
Rebecca McLoughlin ◽  
Suzanne Brook ◽  
...  
Keyword(s):  
Systematic Review ◽  
Manual Therapy ◽  
Trigger Point ◽  
Meta Analysis ◽  
Chronic Noncancer Pain ◽  
Noncancer Pain

Prescriber adherence to guidelines for chronic noncancer pain management with opioids: Systematic review and meta-analysis.

2020 ◽  
Vol 39 (5) ◽  
pp. 430-451 ◽  
Author(s):  
Mohammad A. Hossain ◽  
Michael Asamoah-Boaheng ◽  
Oluwatosin A. Badejo ◽  
Louise V. Bell ◽  
Norman Buckley ◽  
...  
Keyword(s):  
Systematic Review ◽  
Pain Management ◽  
Meta Analysis ◽  
Adherence To Guidelines ◽  
Chronic Noncancer Pain ◽  
Noncancer Pain

All-Cause and Overdose Mortality Risk Among People Prescribed Opioids: A Systematic Review and Meta-analysis

Pain Medicine ◽  
2020 ◽  
Vol 21 (12) ◽  
pp. 3700-3711
Author(s):  
Sarah Larney ◽  
Amy Peacock ◽  
Lucy T Tran ◽  
Emily Stockings ◽  
Damian Santomauro ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Mortality Rates ◽  
Chronic Noncancer Pain ◽  
Crude Mortality Rate ◽  
Crude Mortality ◽  
Standardized Mortality Ratios ◽  
Noncancer Pain ◽  
Overdose Mortality ◽  
Substantial Heterogeneity

Abstract Objective To estimate all-cause and overdose crude mortality rates and standardized mortality ratios among people prescribed opioids for chronic noncancer pain and risk of overdose death in this population relative to people with similar clinical profiles but not prescribed opioids. Design Systematic review and meta-analysis. Methods Medline, Embase, and PsycINFO were searched in February 2018 and October 2019 for articles published beginning 2009. Due to limitations in published studies, we revised our inclusion criteria to include cohort studies of people prescribed opioids, excluding those studies where people were explicitly prescribed opioids for the treatment of opioid use disorder or acute cancer or palliative pain. We estimated pooled all-cause and overdose crude mortality rates using random effects meta-analysis models. No studies reported standardized mortality ratios or relative risks. Results We included 13 cohorts with 6,029,810 participants. The pooled all-cause crude mortality rate, based on 10 cohorts, was 28.8 per 1000 person-years (95% CI = 17.9–46.4), with substantial heterogeneity (I2 = 99.9%). The pooled overdose crude mortality rate, based on six cohorts, was 1.1 per 1000 person-years (95% CI = 0.4–3.4), with substantial heterogeneity (I2 = 99.5%), but indications for opioid prescribing and opioid exposure were poorly ascertained. We were unable to estimate mortality in this population relative to clinically similar populations not prescribed opioids. Conclusions Methodological limitations in the identified literature complicate efforts to determine the overdose mortality risk of people prescribed opioids. There is a need for large-scale clinical trials to assess adverse outcomes in opioid prescribing, especially for chronic noncancer pain.

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