scholarly journals Anesthetic outcomes in pediatric patients with COVID‐19: A matched cohort study

2021 ◽  
Author(s):  
Jessica A. Cronin ◽  
Jonathon H. Nelson ◽  
Ian Farquhar ◽  
Barbara Braffett ◽  
Ionut Bebu ◽  
...  
Keyword(s):  
Cohort Study ◽  
Pediatric Patients ◽  
Matched Cohort ◽  
Matched Cohort Study ◽  
Anesthetic Outcomes

scholarly journals Incidence of Nephrotoxicity Among Pediatric Patients Receiving Vancomycin With Either Piperacillin–Tazobactam or Cefepime: A Cohort Study

2018 ◽  
Vol 8 (3) ◽  
pp. 221-227 ◽  
Author(s):  
Kathryn M Cook ◽  
Jessica Gillon ◽  
Alison G Grisso ◽  
Ritu Banerjee ◽  
Natalia Jimenez-Truque ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Cohort Study ◽  
Pediatric Patients ◽  
Kidney Injury ◽  
Matched Cohort ◽  
Matched Cohort Study

In this matched-cohort study of pediatric inpatients, 28.9% of those treated with a combination of piperacillin–tazobactam and vancomycin developed acute kidney injury, compared to 7.9% in those treated with cefepime and vancomycin (P < .001).

scholarly journals 906. Surgical Site Infections in Children with Beta-Lactam Allergy: A Matched Cohort Study

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S487-S487
Author(s):  
Felicia Scaggs Huang ◽  
Colleen Mangeot ◽  
Heidi Sucharew ◽  
Katherine Simon ◽  
Joshua D Courter ◽  
...  
Keyword(s):  
Cohort Study ◽  
Pediatric Patients ◽  
Significant Proportion ◽  
Surgical Site Infections ◽  
Matched Cohort ◽  
Antibiotic Regimen ◽  
Beta Lactam ◽  
Improvement Program ◽  
Matched Cohort Study ◽  
Significant Difference

Abstract Background Surgical site infections (SSIs) are a significant cause of morbidity and mortality. The administration of appropriate pre-operative antimicrobial prophylaxis (AMP) reduces SSI risk and beta-lactam antibiotics are considered the most effective agents. Studies in adult patients found increased SSI risk in patients with documented beta-lactam allergy (BLA) due to use of second line AMP agents. The SSI risk in BLA pediatric patients is not well-described. Methods We conducted a retrospective matched cohort study of patients (1-19 years-old) who underwent a surgical procedure at a quaternary pediatric hospital during 2010-2017. Patients with documented BLA at the time of surgery were matched 1:1 to patients with no BLA by age at surgery, National Surgical Quality Improvement Program (NSQIP) category, surgical calendar year, and presence of complex chronic conditions (CCC). AMP by BLA status was considered appropriate if recommended by the 2013 American Society of Health-System Pharmacists (ASHP) guidelines, antibiotic class appropriate, or recommended by an infectious disease physician. McNemar’s test was used to assess differences in SSI rates and antibiotic regimen appropriate for BLA status between BLA and no BLA groups. Results Of the 11878 surgical procedures among 9781 patients during the study period, 1021(9%) of patients had a reported BLA and we matched 972. SSI was rare in both groups and there was no significant difference in rates (18 (1.9%) in no BLA, 17 (1.8%) in BLA, p=1.0). BLA were more likely to receive an antibiotic regimen considered inappropriate for BLA status (22%) compared to no BLA (3%) with 89% receiving a beta-lactam-containing AMP regimen (p&lt; 0.01). Conclusion BLA was not associated with increased SSI risk in the pediatric patients studied. Interestingly, a significant proportion of children with a documented allergy received a beta-lactam for AMP. This suggests some providers recognize that allergy labels are inaccurate and may be comfortable administering beta-lactam AMP regardless of allergy status. Disclosures All Authors: No reported disclosures

Bimodal analgesia vs fentanyl in pediatric patients undergoing bilateral myringotomy and tympanostomy tube placement: a propensity matched cohort study

2016 ◽  
Vol 32 ◽  
pp. 162-168 ◽  
Author(s):  
Maxie L. Phillips ◽  
Bryan C. Willis ◽  
Aaron J. Broman ◽  
Humphrey V. Lam ◽  
Thanh T. Nguyen ◽  
...  
Keyword(s):  
Cohort Study ◽  
Pediatric Patients ◽  
Tube Placement ◽  
Matched Cohort ◽  
Tympanostomy Tube ◽  
Matched Cohort Study

scholarly journals Outcomes among pediatric patients with cancer who are treated on trial versus off trial: A matched cohort study

Cancer ◽  
2020 ◽  
Vol 126 (15) ◽  
pp. 3471-3482 ◽  
Author(s):  
Marilyn M. Schapira ◽  
Evelyn M. Stevens ◽  
James E. Sharpe ◽  
Lauren Hochman ◽  
Joseph G. Reiter ◽  
...  
Keyword(s):  
Cohort Study ◽  
Pediatric Patients ◽  
Matched Cohort ◽  
Matched Cohort Study ◽  
Patients With Cancer
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