scholarly journals The predictive value of the Pleth Variability Index on fluid responsiveness in spontaneously breathing anaesthetized children—A prospective observational study

2020 ◽  
Vol 30 (10) ◽  
pp. 1124-1131
Author(s):  
Frank Weber ◽  
Bharat K. Rashmi ◽  
Gülhan Karaoz‐Bulut ◽  
Jaap Dogger ◽  
Iris J. Heer ◽  
...  
Keyword(s):  
Observational Study ◽  
Fluid Responsiveness ◽  
Predictive Value ◽  
Prospective Observational Study ◽  
Pleth Variability Index ◽  
Variability Index ◽  
Spontaneously Breathing

Predictive value of thyroxine for prognosis in pediatric septic shock: a prospective observational study

2020 ◽  
Vol 33 (5) ◽  
pp. 653-659
Author(s):  
Jia Song ◽  
Yun Cui ◽  
Chunxia Wang ◽  
Jiaying Dou ◽  
Huijie Miao ◽  
...  
Keyword(s):  
Septic Shock ◽  
Thyroid Hormone ◽  
Observational Study ◽  
Hospital Mortality ◽  
Predictive Value ◽  
Prospective Observational Study ◽  
Threshold Value ◽  
Nonthyroidal Illness ◽  
Hormone Levels ◽  
Thyroid Hormone Levels

AbstractBackgroundThyroid hormone plays an important role in the adaptation of metabolic function to critically ill. The relationship between thyroid hormone levels and the outcomes of septic shock is still unclear. The aim of this study was to assess the predictive value of thyroid hormone for prognosis in pediatric septic shock.MethodsWe performed a prospective observational study in a pediatric intensive care unit (PICU). Patients with septic shock were enrolled from August 2017 to July 2019. Clinical and laboratory indexes were collected, and thyroid hormone levels were measured on PICU admission.ResultsNinety-three patients who fulfilled the inclusion criteria were enrolled in this study. The incidence of nonthyroidal illness syndrome (NTIS) was 87.09% (81/93) in patients with septic shock. Multivariate logistic regression analysis showed that T4 level was independently associated with in-hospital mortality in patients with septic shock (OR: 0.965, 95% CI: 0.937–0.993, p = 0.017). The area under receiver operating characteristic (ROC) curve (AUC) for T4 was 0.762 (95% CI: 0.655–0.869). The cutoff threshold value of 58.71 nmol/L for T4 offered a sensitivity of 61.54% and a specificity of 85.07%, and patients with T4 < 58.71 nmol/L showed high mortality (60.0%). Moreover, T4 levels were negatively associated with the pediatric risk of mortality III scores (PRISM III), lactate (Lac) level in septic shock children.ConclusionsNonthyroidal illness syndrome is common in pediatric septic shock. T4 is an independent predictor for in-hospital mortality, and patients with T4 < 58.71 nmol/L on PICU admission could be with a risk of hospital mortality.

Accuracy of the pleth variability index to predict fluid responsiveness depends on the perfusion index

2011 ◽  
Vol 55 (6) ◽  
pp. 686-693 ◽  
Author(s):  
O. BROCH ◽  
B. BEIN ◽  
M. GRUENEWALD ◽  
J. HÖCKER ◽  
J. SCHÖTTLER ◽  
...  
Keyword(s):  
Fluid Responsiveness ◽  
Perfusion Index ◽  
Pleth Variability Index ◽  
Predict Fluid Responsiveness ◽  
Variability Index

360 Predictive Value of Clinical Assessment of Severe Frostbite Injury - Preliminary Outcomes from a Prospective Observational Study

2018 ◽  
Vol 39 (suppl_1) ◽  
pp. S150-S150
Author(s):  
A M Lacey ◽  
J C Moore ◽  
A B Whitley ◽  
G Punjabi ◽  
T Masters ◽  
...  
Keyword(s):  
Observational Study ◽  
Clinical Assessment ◽  
Predictive Value ◽  
Prospective Observational Study
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