A retrospective observational study of acquired subglottic stenosis using low-pressure, high-volume cuffed endotracheal tubes

2018 ◽  
Vol 28 (12) ◽  
pp. 1136-1141 ◽  
Author(s):  
David Greaney ◽  
John Russell ◽  
Ian Dawkins ◽  
Martina Healy
Keyword(s):  
Observational Study ◽  
High Volume ◽  
Low Pressure ◽  
Subglottic Stenosis ◽  
Retrospective Observational Study ◽  
Endotracheal Tubes

Experimental Induction of Squamous Metaplasia in the Dog Trachea with Cuffed Endotracheal Tubes

1982 ◽  
Vol 90 (5) ◽  
pp. 555-560 ◽  
Author(s):  
James M. Severson ◽  
Gary W. Ketter ◽  
Thomas P. Belson ◽  
Roland D. Paegle ◽  
Robert J. Toohill
Keyword(s):  
Experimental Model ◽  
Squamous Metaplasia ◽  
High Volume ◽  
Low Pressure ◽  
Distal Portion ◽  
Histologic Study ◽  
Tracheal Mucosa ◽  
Endotracheal Tubes ◽  
Experimental Induction ◽  
Prolonged Contact

Clinical reports cite the development of squamous metaplasia in tracheas following tracheostomy, laryngectomy, and cuffed intubation. The purpose of this study was (1) to develop an experimental model using the dog trachea and study the effects of prolonged cuffed intubation and (2) to determine whether squamous metaplasia is produced by prolonged contact of the endotracheal cuff with the tracheal mucosa. Modifications of widely used high-volume, low-pressure 8-mm endotracheal tubes were made with the distal portion of the tube, its cuff, and the inflating catheter attached. This model formed an implantable cuffed tube approximately 8 cm in length. The dogs remained intubated for 14 days, at which time they were killed; seven animals were available for histologic study. Varying degrees of squamous metaplasia were produced in all animals.

Migration of polyurethane high-volume low-pressure cuffed endotracheal tubes after neck flexion and extension

2013 ◽  
Vol 27 (4) ◽  
pp. 633-634 ◽  
Author(s):  
Devanand Mangar ◽  
Collin J. Sprenker ◽  
Rachel A. Karlnoski ◽  
Robert K. Dodson ◽  
Bill H. Brashears ◽  
...  
Keyword(s):  
High Volume ◽  
Low Pressure ◽  
Neck Flexion ◽  
Endotracheal Tubes ◽  
Flexion And Extension

scholarly journals New geographic model of care to manage the post-COVID-19 elective surgery aftershock in England: a retrospective observational study

BMJ Open ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. e042392
Author(s):  
Jonathan Clarke ◽  
Alice Murray ◽  
Sheraz Rehan Markar ◽  
Mauricio Barahona ◽  
James Kinross
Keyword(s):  
Observational Study ◽  
Surgical Procedures ◽  
Elective Surgery ◽  
Supply And Demand ◽  
Surgical Care ◽  
High Volume ◽  
Waiting Lists ◽  
Low Risk ◽  
Retrospective Observational Study ◽  
Risk Patients

ObjectivesThe suspension of elective surgery during the COVID-19 pandemic is unprecedented and has resulted in record volumes of patients waiting for operations. Novel approaches that maximise capacity and efficiency of surgical care are urgently required. This study applies Markov multiscale community detection (MMCD), an unsupervised graph-based clustering framework, to identify new surgical care models based on pooled waiting-lists delivered across an expanded network of surgical providers.DesignRetrospective observational study using Hospital Episode Statistics.SettingPublic and private hospitals providing surgical care to National Health Service (NHS) patients in England.ParticipantsAll adult patients resident in England undergoing NHS-funded planned surgical procedures between 1 April 2017 and 31 March 2018.Main outcome measuresThe identification of the most common planned surgical procedures in England (high-volume procedures (HVP)) and proportion of low, medium and high-risk patients undergoing each HVP. The mapping of hospitals providing surgical care onto optimised groupings based on patient usage data.ResultsA total of 7 811 891 planned operations were identified in 4 284 925 adults during the 1-year period of our study. The 28 most common surgical procedures accounted for a combined 3 907 474 operations (50.0% of the total). 2 412 613 (61.7%) of these most common procedures involved ‘low risk’ patients. Patients travelled an average of 11.3 km for these procedures. Based on the data, MMCD partitioned England into 45, 16 and 7 mutually exclusive and collectively exhaustive natural surgical communities of increasing coarseness. The coarser partitions into 16 and seven surgical communities were shown to be associated with balanced supply and demand for surgical care within communities.ConclusionsPooled waiting-lists for low-risk elective procedures and patients across integrated, expanded natural surgical community networks have the potential to increase efficiency by innovatively flexing existing supply to better match demand.

Hemmkörperentwicklung bei Hämophilie-Patienten nach Präparate wechsel

2012 ◽  
Vol 32 (S 01) ◽  
pp. S39-S42 ◽  
Author(s):  
S. Kocher ◽  
G. Asmelash ◽  
V. Makki ◽  
S. Müller ◽  
S. Krekeler ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Observational Study ◽  
Retrospective Observational Study ◽  
Frequent Change ◽  
Patient Age ◽  
Treatment Regimens ◽  
Patient Âgé ◽  
The Relationship ◽  
Observation Period

SummaryThe retrospective observational study surveys the relationship between development of inhibitors in the treatment of haemophilia patients and risk factors such as changing FVIII products. A total of 119 patients were included in this study, 198 changes of FVIII products were evaluated. Results: During the observation period of 12 months none of the patients developed an inhibitor, which was temporally associated with a change of FVIII products. A frequent change of FVIII products didn’t lead to an increase in inhibitor risk. The change between plasmatic and recombinant preparations could not be confirmed as a risk factor. Furthermore, no correlation between treatment regimens, severity, patient age and comorbidities of the patients could be found.

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