Optimization of initial propofol bolus dose for EEG Narcotrend Index-guided transition from sevoflurane induction to intravenous anesthesia in children

2017 ◽  
Vol 27 (4) ◽  
pp. 425-432 ◽  
Author(s):  
Nils Dennhardt ◽  
Dietmar Boethig ◽  
Christiane Beck ◽  
Sebastian Heiderich ◽  
Martin Boehne ◽  
...  
Keyword(s):  
Bolus Dose ◽  
Intravenous Anesthesia ◽  
Narcotrend Index

Effects of Human Antithrombin III on Mortality and Blood Coagulation Induced in Rabbits by Endotoxin

1984 ◽  
Vol 51 (02) ◽  
pp. 232-235 ◽  
Author(s):  
D C Triantaphyllopoulos
Keyword(s):  
Blood Coagulation ◽  
Bolus Dose ◽  
Antithrombin Iii ◽  
Coagulation Parameters ◽  
E Coli ◽  
At Iii ◽  
Baseline Values

SummaryTwenty-one rabbits were infused with 20μg/kg/hr of E. coli endotoxin for 6 hr. Eight of the animals were preinjected immediately before the infusion of endotoxin, with a bolus dose of human AT III calculated to increase the antithrombin content of the plasma by about 4 units/ml. All eight animals which were preinjected with AT III survived, while 5 of the 13 control rabbits infused with endotoxin alone died. The changes in coagulation parameters from the baseline values, between the 8 control rabbits which survived and the 8 animals which were preinjected with AT III were compared. The concentration of the preinjected human AT III declined significantly faster (P: <0.01) than that of the native rabbit AT III. AT III prevented the decline of F.XII throughout the infusion of the endotoxin. However, the decline in F.V, fibrinogen, prothrombin and platelets was not affected (P: >0.5) by the injection of AT III.

The Anticoagulant Effect of Heparinoid Org 10172 During Haemodialysis: An Objective Assessment

1986 ◽  
Vol 55 (02) ◽  
pp. 271-275 ◽  
Author(s):  
Helen Ireland ◽  
D A Lane ◽  
Angela Flynn ◽  
E Anastassiades ◽  
J R Curtis
Keyword(s):  
Renal Failure ◽  
Bolus Dose ◽  
Bolus Injection ◽  
Objective Assessment ◽  
Factor Xa ◽  
Fibrin Clot ◽  
Natural Origin ◽  
Fibrin Formation ◽  
Single Bolus Injection

SummaryThe heparinoid of natural origin Org 10172 has anti-factor Xa activity but minimal anti-thrombin activity, and little effect upon broad spectrum assays such as the KCCT in vitro. Its anticoagulant effects have been compared to those of commercial heparin in 7 patients undergoing haemodialysis for chronic renal failure. Commercial heparin was administered in a dose (5,000 iu bolus + 1,500 iu/hour continuous iv infusion) previously shown to inhibit fibrin formation during haemodialysis. This produced mean anti-factor Xa levels in plasma between 0.7-1.0 iu/ml and largely suppressed fibrin formation for 5 h dialysis measured as mean FPA levels in plasma. Administration of Org 10172 as a bolus of 1,350 anti-factor Xa u or 2,000-2,400 anti-factor Xa u produced plasma anti-factor Xa levels of less than 0.5 u/ml and allowed fibrin clot and FPA generation during dialysis. Org 10172 administered as a bolus dose of 4,000-4,800 anti-factor Xa u produced mean anti-factor Xa levels of greater than 0.5 u/ml, allowed dialysis of 6 patients for 5 h and appreciably suppressed FPA generation during dialysis, with little effect on the KCCT.It is concluded that the anti-factor Xa activity of Org 10172 may reflect its ability to inhibit fibrin during dialysis and that single bolus injection of Org 10172 may be a useful alternative method of achieving anticoagulation.

Analysis of Parameters Determining the Frequency and Intensity of Pneumatocele in Patients with CPA Tumor Operated in Sitting Position with Total Intravenous Anesthesia

Skull Base ◽  
2007 ◽  
Vol 17 (S 1) ◽  
Author(s):  
Stanislaw Kwiek ◽  
Hanna Doleżych ◽  
Wojciech Ślusarczyk ◽  
Piotr Bażowski ◽  
Izabela Duda ◽  
...  
Keyword(s):  
Total Intravenous Anesthesia ◽  
Sitting Position ◽  
Intravenous Anesthesia

Total Intravenous Anesthesia pada Geriatri dengan Meningioma Parietalis

2015 ◽  
Vol 4 (2) ◽  
pp. 112-118
Author(s):  
Rebecca Sidhapramudita Mangastuti ◽  
◽  
Nazaruddin Umar ◽  
Marsudi Rasman ◽  
◽  
...  
Keyword(s):  
Total Intravenous Anesthesia ◽  
Intravenous Anesthesia

Total Intravenous Anesthesia pada Geriatri dengan Meningioma Parietalis

2015 ◽  
Vol 4 (2) ◽  
pp. 112-18
Author(s):  
Rebecca Sidhapramudita Mangastuti ◽  
◽  
Nazaruddin Umar ◽  
Marsudi Rasman ◽  
◽  
...  
Keyword(s):  
Total Intravenous Anesthesia ◽  
Intravenous Anesthesia
Sign in / Sign up

Export Citation Format

Share Document