Reply to Greenstein, Alan; Morton, Neil; Patil, Vinodkumar, regarding their comment on “Optimized preoperative fasting times decrease ketone body concentration and stabilize mean arterial blood pressure during induction of anesthesia in children younger than 36 months: a prospective observational cohort study”

2017 ◽  
Vol 27 (3) ◽  
pp. 325-326
Author(s):  
Nils Dennhardt ◽  
Christiane Beck ◽  
Dirk Huber ◽  
Robert Sümpelmann
Keyword(s):  
Blood Pressure ◽  
Cohort Study ◽  
Mean Arterial Blood Pressure ◽  
Ketone Body ◽  
Observational Cohort Study ◽  
Prospective Observational Cohort Study ◽  
Preoperative Fasting ◽  
Arterial Blood ◽  
Observational Cohort ◽  
Body Concentration

scholarly journals Protocol for the HAPPY Hearts study: cardiovascular screening for the early detection of future adverse cardiovascular outcomes in middle-aged and older women: a prospective, observational cohort study

BMJ Open ◽  
2017 ◽  
Vol 7 (11) ◽  
pp. e018249 ◽  
Author(s):  
Kevin F Boreskie ◽  
D Scott Kehler ◽  
Eduardo C Costa ◽  
Pedro C Cortez ◽  
Ivan Berkowitz ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cohort Study ◽  
Older Women ◽  
Cardiovascular Outcomes ◽  
Observational Cohort Study ◽  
Moderate Intensity ◽  
Prospective Observational Cohort Study ◽  
Middle Aged ◽  
Observational Cohort ◽  
Manitoba Health

IntroductionEfforts to identify individuals at a higher risk for adverse cardiovascular outcomes focus on traditional risk factors, such as age, sex, smoking status, blood pressure and and cholesterol; however, this approach does not directly assess cardiovascular function and may underestimate the risk of experiencing adverse cardiovascular outcomes in women. This prospective, observational cohort study will examine the ability of the Heart Attack Prevention Program for You (HAPPY) Hearts screening protocol, a series of non-invasive procedures to identify middle-aged and older women who are at an elevated risk for experiencing an adverse cardiovascular event in the 5-year period after screening. The predictive value of the HAPPY Hearts protocol will also be compared with the Framingham Risk Score to determine the sensitivity for estimating risk for an adverse cardiovascular outcome.Methods and analysisOne thousand women 55 years of age or older will be recruited to be screened by the HAPPY Hearts protocol. This involves the cardiovascular assessment of resting blood pressure, blood pressure response to 3 min of moderate intensity exercise and large and small arterial elasticity. The participants will be classified into risk categories based on these measures. The incidence of the following adverse cardiovascular outcomes will be assessed in the 5-year period after screening in both groups: ischaemic heart disease, acute myocardial infarction, stroke, percutaneous coronary intervention, coronary bypass surgery, congestive heart failure and new hypertension.Ethics and disseminationInformation gathered in this research will be published in peer-reviewed journals and presented in a programme evaluation report to inform Manitoba Health and key stakeholders about the outcomes of the study. The University of Manitoba Health Research Ethics Board has approved the study protocol V.2.0, dated 29 September 2014 (H2014:224).Trial registration numberNCT02863211.

scholarly journals Effects of Two Community-Based Exercise Programs on Adherence, Cardiometabolic Markers, and Body Composition in Older People with Cardiovascular Risk Factors: A Prospective Observational Cohort Study

2020 ◽  
Vol 10 (4) ◽  
pp. 176
Author(s):  
Esther García-Sánchez ◽  
Jacobo Á. Rubio-Arias ◽  
Vicente Ávila-Gandía ◽  
F. Javier López-Román ◽  
Juan F. Menarguez-Puche
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Cohort Study ◽  
Physical Exercise ◽  
Exercise Program ◽  
Observational Cohort Study ◽  
Prospective Observational Cohort Study ◽  
Community Based ◽  
Observational Cohort ◽  
Observation Period

Cardiovascular disease is one of the leading causes of death globally, and cardiovascular risk factors (CRFs) are major behavioral risk factors. Therefore, community-based programs are being designed based on the prescription of physical exercise from primary care centers to improve people’s health through changes in lifestyle. The objective was to compare the effects of two types of community exercise on adherence, lipid profile, body composition and blood pressure. A prospective observational cohort study was designed with two cohorts of study depending on the duration and type of physical exercise program performed. Fifty-one participants (82.4% women) with CRF completed the observation period in which they carried out a short-term, non-individualized exercise program (3 months), and 42 participants (71.4% women) with CRF completed the observation period in which they conducted a long-term, individualized exercise program (6 months). The results suggest that participants who carried out the longer program with an individualized progression produced greater adherence to physical exercise and a decrease in diastolic blood pressure. In addition, LDL and insulin levels decreased in both groups. Therefore, our results suggest that a longer duration and individualized evolution of the loads of a community exercise program lead to higher levels of physical activity (PA) and improvements diastolic blood pressure.

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