The effects of dexmedetomidine on early stage renal functions in pediatric patients undergoing cardiac angiography using non-ionic contrast media: a double-blind, randomized clinical trial

2014 ◽  
Vol 24 (4) ◽  
pp. 426-432 ◽  
Author(s):  
Adnan Bayram ◽  
Ayşe Ülgey ◽  
Ali Baykan ◽  
Nazmi Narin ◽  
Figen Narin ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Contrast Media ◽  
Randomized Clinical Trial ◽  
Pediatric Patients ◽  
Early Stage ◽  
Double Blind ◽  
Renal Functions ◽  
Cardiac Angiography ◽  
Ionic Contrast

scholarly journals Efficacy of fructooligosaccharide versus placebo for treatment of acute diarrhea in children: A double-blind randomized clinical trial

2016 ◽  
Vol 45 (2) ◽  
pp. 65
Author(s):  
Reni Suryanty ◽  
Supriatmo Supriatmo ◽  
Berlian Hasibuan ◽  
Atan Baas Sinuhaji
Keyword(s):  
Clinical Trial ◽  
Body Weight ◽  
Placebo Group ◽  
Randomized Clinical Trial ◽  
Outpatient Clinic ◽  
Acute Diarrhea ◽  
Pediatric Patients ◽  
Inclusion Criteria ◽  
Double Blind ◽  
Significant Difference

Objective To compare the efficacy of fructooligosaccharide (FOS)versus placebo in pediatric patients with acute diarrhea with re-gard to duration and frequency of diarrhea and the volume andconsistency of the stools.Methods This double-blind randomized clinical trial was carriedout from July to November 2003 in the pediatric intensive careunit, outpatient clinic, and pediatric ward of Adam Malik Hospitaland Pirngadi Hospital, Medan. Subjects were children and infantsaged 4 to 24 months suffering from acute diarrhea without dehy-dration or with mild to moderate dehydration whose parents gaveconsent. Children included in this trial received tablets of either600 mg FOS or 761 mg fructulin as placebo. Patients with mild tomoderate dehydration were initially rehydrated according to theWHO protocol. Afterwards, 10 tablets of FOS or placebo were givento each subject to be taken twice daily. In subjects without dehy-dration, the tablets were given by their parents. Daily follow-upwas performed, in which body weight, temperature, duration andfrequency of diarrhea, and the volume and consistency of stoolswere recorded. For outpatients, home visits were made.Results Out of 142 children who met inclusion criteria, 135 com-pleted the study. These consisted of 68 children in the FOS groupand 67 in the placebo group. Subjects were mostly <12 months ofage (57.0%), male (57.8%), and moderately malnourished (34.1%).There was no statistically significant difference between both groupsin the duration and frequency of diarrhea and the volume and con-sistency of stools (P>0.05).Conclusion There is no effect of the administration of FOS assupplemental therapy on the duration and frequency of diarrheaand on the volume and consistency of stools in children with acutediarrhea

Lumbar Myelography with Iohexol and Metrizamide

1984 ◽  
Vol 25 (5) ◽  
pp. 365-368 ◽  
Author(s):  
T. Hindmarsh ◽  
S. E. Ekholm ◽  
D. K. Kido ◽  
L. Sahler ◽  
M. Sands
Keyword(s):  
Clinical Trial ◽  
Contrast Media ◽  
Spinal Stenosis ◽  
Disc Herniation ◽  
Subarachnoid Space ◽  
Adverse Reactions ◽  
Double Blind ◽  
Lumbar Myelography ◽  
Double Blind Clinical Trial ◽  
Ionic Contrast

Two non-ionic contrast media, iohexol and metrizamide, were compared in a double-blind clinical trial which included 50 patients who underwent lumbar myelography for disc herniation or spinal stenosis. The frequency of adverse reactions was lower for iohexol which is recommended for extended trials and for examination of other compartments of the subarachnoid space.

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