Comments on vitamin D and sensitization, asthma treatment, and lung function development

2021 ◽  
Vol 32 (6) ◽  
pp. 1137-1140
Author(s):  
Philippe Eigenmann
Keyword(s):  
Vitamin D ◽  
Lung Function ◽  
Asthma Treatment

Questioning Asthma Treatment Study

PEDIATRICS ◽  
1991 ◽  
Vol 88 (1) ◽  
pp. 186-186
Author(s):  
ASHER TAL ◽  
NISSIM LEVY ◽  
Jacob E. Bearman
Keyword(s):  
Emergency Department ◽  
Lung Function ◽  
Young Children ◽  
Respiratory Rate ◽  
Peak Expiratory Flow ◽  
Flow Rate ◽  
Peak Expiratory Flow Rate ◽  
Acute Asthma ◽  
Asthma Treatment ◽  
Function Measure

In Reply.— We thank Drs McJunkin and Stallo for their interest in our paper. Their suggestion of using objective lung function measurements in young children and infants with acute asthma in the emergency department is impractical. The pulmonary index score we used includes at least one important lung function measure, namely, respiratory rate; this score also has been shown to be very reliable in children.1 Although we routinely use the peak expiratory flow rate in children in the emergency department, most of our patients were younger than 3 years of age and could not cooperate with this objective measurement.

No association between vitamin D and atopy, asthma, lung function or atopic dermatitis: a prospective study in adults

Allergy ◽  
2015 ◽  
Vol 70 (11) ◽  
pp. 1501-1504 ◽  
Author(s):  
B. H. Thuesen ◽  
N. G. Heede ◽  
L. Tang ◽  
T. Skaaby ◽  
J. P. Thyssen ◽  
...  
Keyword(s):  
Vitamin D ◽  
Atopic Dermatitis ◽  
Lung Function ◽  
Prospective Study ◽  
A Prospective Study

scholarly journals Effect of Monthly, High-Dose, Long-Term Vitamin D on Lung Function: A Randomized Controlled Trial

Nutrients ◽  
2017 ◽  
Vol 9 (12) ◽  
pp. 1353 ◽  
Author(s):  
John Sluyter ◽  
Carlos Camargo ◽  
Debbie Waayer ◽  
Carlene Lawes ◽  
Les Toop ◽  
...  
Keyword(s):  
Vitamin D ◽  
Randomized Controlled Trial ◽  
Lung Function ◽  
Controlled Trial ◽  
High Dose ◽  
Randomized Controlled

Association Between Severe Vitamin D Deficiency, Lung Function and Asthma Control

2017 ◽  
Vol 53 (4) ◽  
pp. 186-191 ◽  
Author(s):  
Seda Beyhan-Sagmen ◽  
Ozgur Baykan ◽  
Baran Balcan ◽  
Berrin Ceyhan
Keyword(s):  
Vitamin D ◽  
Lung Function ◽  
Vitamin D Deficiency ◽  
Asthma Control ◽  
Severe Vitamin

scholarly journals Meta-analysis of vitamin D and lung function in patients with asthma

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Jian Liu ◽  
Yong-Quan Dong ◽  
Jie Yin ◽  
Jian Yao ◽  
Jie Shen ◽  
...  
Keyword(s):  
Vitamin D ◽  
Lung Function ◽  
Meta Analysis ◽  
Serum Vitamin ◽  
Forced Expiratory Volume ◽  
Asthma Control Test ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Asthma Patients ◽  
Sufficient Vitamin

Abstract Background There is growing literature suggesting a link between vitamin D and asthma lung function, but the results from systematic reviews are conflicting. We conducted this meta-analysis to investigate the relation between serum vitamin D and lung function in asthma patients. Methods Major databases, including OVID, MEDLINE, Web of Science and PUBMED, were searched until 10th October 2018. All published observational studies related to vitamin D and asthma were extracted. All meta-analyses were performed using Review Manager 5.3.5. Results This quantitative synthesis found that asthma patients with low vitamin D levels had lower forced expiratory volume In 1 s (FEV1) (mean difference (MD) = − 0.1, 95% CI = − 0.11 to − 0.08,p < 0.01;I2 = 49%, p = 0.12) and FEV1% (MD = − 10.02, 95% CI = − 11 to − 9.04, p < 0.01; I2 = 0%, p = 0.82) than those with sufficient vitamin D levels. A positive relation was found between vitamin D and FEV1 (r = 0.12, 95% CI = 0.04 to 0.2, p = 0.003; I2 = 59%,p = 0.01), FEV1% (r = 0.19, 95% CI = 0.13 to 0.26, p < 0.001; I2 = 42%, p = 0.11), forced vital capacity (FVC) (r = 0.17, 95% CI = 0.00 to 0.34, p = 0.05; I2 = 60%, p = 0.04), FEV1/FVC (r = 0.4, 95% CI = 0.3 to 0.51, p < 0.001; I2 = 48%, p = 0.07), and the asthma control test (ACT) (r = 0.33, 95% CI = 0.2 to 0.47, p < 0.001; I2 = 0%, p = 0.7). Subgroup analysis indicated that the positive correlation between vitamin D and lung function remained significant in both children and adults. Conclusions Our meta-analysis suggested that serum vitamin D levels may be positively correlated with lung function in asthma patients. Future comprehensive studies are required to confirm these relations and to elucidate potential mechanisms.

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