Hydrolysed formula and allergy prevention

2021 ◽  
Vol 32 (4) ◽  
pp. 667-669
Author(s):  
Jon Genuneit ◽  
Robert J. Boyle
Children ◽  
2021 ◽  
Vol 8 (6) ◽  
pp. 497
Author(s):  
Aikaterini Anagnostou

Background: Food allergies are common, affecting 1 in 13 school children in the United States and their prevalence is increasing. Many misconceptions exist with regards to food allergy prevention, diagnosis and management. Objective: The main objective of this review is to address misconceptions with regards to food allergies and discuss the optimal, evidence-based approach for patients who carry this diagnosis. Observations: Common misconceptions in terms of food allergy prevention include beliefs that breastfeeding and delayed introduction of allergenic foods prevent the development of food allergies. In terms of diagnosis, statements such as ‘larger skin prick tests or/and higher levels of food-specific IgE can predict the severity of food-induced allergic reactions’, or ‘Tryptase is always elevated in food-induced anaphylaxis’ are inaccurate. Additionally, egg allergy is not a contraindication for receiving the influenza vaccine, food-allergy related fatalities are rare and peanut oral immunotherapy, despite reported benefits, is not a cure for food allergies. Finally, not all infants with eczema will develop food allergies and epinephrine auto-injectors may unfortunately be both unavailable and underused in food-triggered anaphylaxis. Conclusions and relevance: Healthcare professionals must be familiar with recent evidence in the food allergy field and avoid common misunderstandings that may negatively affect prevention, diagnosis and management of this chronic disease.


2021 ◽  
Vol 51 (1) ◽  
pp. 4-5
Author(s):  
Robert J. Boyle ◽  
Mohamed H. Shamji
Keyword(s):  

Author(s):  
Patricia Macchiaverni ◽  
Akila Rekima ◽  
Lieke van den Elsen ◽  
Harald Renz ◽  
Valerie Verhasselt

2008 ◽  
Vol 121 (2) ◽  
pp. S200-S200
Author(s):  
R TEICH ◽  
N BLUMER ◽  
C PATRASCAN ◽  
H GARN ◽  
H RENZ
Keyword(s):  

Author(s):  
Elissa M. Abrams ◽  
Marcus Shaker ◽  
Matthew Greenhawt ◽  
Douglas P. Mack

2017 ◽  
Vol 184 ◽  
pp. 13-18 ◽  
Author(s):  
Elissa M. Abrams ◽  
Matthew Greenhawt ◽  
David M. Fleischer ◽  
Edmond S. Chan

2017 ◽  
Vol 70 (Suppl. 2) ◽  
pp. 38-45 ◽  
Author(s):  
Michael D. Cabana

Asthma, eczema, food allergy, and allergic rhinitis are some of the most common pediatric, chronic conditions in the world. Breastfeeding is the optimal way to feed all infants. For those infants who are exposed to infant formula, some studies suggest that certain partially hydrolyzed or extensively hydrolyzed formulas may decrease the risk of allergic disease compared to nonhydrolyzed formulas for children with a family history of atopic disease. Overall, there is some evidence to suggest that partially hydrolyzed whey formulas and extensively hydrolyzed casein formulas may decrease the risk of developing eczema for infants at high risk of allergic disease. The evidence for a preventive effect of hydrolyzed formulas on allergic rhinitis, food allergy, and asthma is inconsistent and insufficient. Finally, the qualitative changes to the peptides by the method of hydrolysis, not just the degree of protein hydrolysis, may have a large influence on the preventive effect of a particular infant formula for the potential risk of allergic disease. As a result, it may be difficult to generalize findings from clinical studies using a specific infant formula to other infant formulas from different manufacturers using different methods of hydrolysis. Further clinical studies are needed to help clinicians identify which infants may benefit from early intervention, as well as which specific hydrolyzed formulas are best suited to decrease the risk of future allergic disease.


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