Transesophageal and invasive electrophysiologic evaluation in children with Wolff-Parkinson-White pattern

2017 ◽  
Vol 40 (7) ◽  
pp. 808-814 ◽  
Author(s):  
Serhat Koca ◽  
Feyza Aysenur Pac ◽  
Ahmet Vedat Kavurt ◽  
Serkan Cay ◽  
Ajda Mihcioglu ◽  
...  
Keyword(s):  
Invasive Electrophysiologic

TAMI-66. FUNCTIONAL ALTERATIONS IN CORTICAL PROCESSING OF SPEECH IN GLIOMA-INFILTRATED CORTEX

2021 ◽  
Vol 23 (Supplement_6) ◽  
pp. vi212-vi212
Author(s):  
alexander Aabedi ◽  
Benjamin Lipkin ◽  
Jasleen Kaur ◽  
Sofia Kakaizada ◽  
Jacob Young ◽  
...  
Keyword(s):  
Cognitive Processing ◽  
Patient Survival ◽  
Malignant Gliomas ◽  
Paracrine Signaling ◽  
Wild Type ◽  
Information Encoding ◽  
Neural Computations ◽  
Recent Developments ◽  
Invasive Electrophysiologic ◽  
Lower Capacity

Abstract INTRODUCTION Recent developments in the biology of malignant gliomas have demonstrated that glioma cells interact with neurons through both paracrine signaling and electrochemical synapses. Glioma-neuron interactions consequently modulate the excitability of local neuronal circuits, and it is unclear the extent to which glioma-infiltrated cortex can meaningfully participate in neural computations. For example, gliomas may result in a local disorganization of activity that impedes the transient synchronization of neural oscillations. Alternatively, glioma-infiltrated cortex may retain the ability to engage in synchronized activity, in a manner similar to normal-appearing cortex, but exhibit other altered spatiotemporal patterns of activity with subsequent impact on cognitive processing. METHODS Here, we acquired invasive electrophysiologic recordings to sample both normal-appearing and glioma-infiltrated cortex during speech initiation in order to measure language task-related circuit dynamics of IDH-wild-type glioblastoma patients. We then applied an information theoretical framework to directly compare the encoding capacity and decodability of signals arising from these regions. RESULTS We find that glioma-infiltrated cortex engages in synchronous activity during task performance in a manner similar to normal-appearing cortex, but recruits a diffuse spatial network. On a temporal scale, we show that glioma-infiltrated cortex has lower capacity for information encoding when performing nuanced tasks such as speech production of monosyllabic versus polysyllabic words. As a result, temporal decoding strategies for distinguishing monosyllabic from polysyllabic words were feasible for signals arising from normal-appearing cortex, but not from glioma-infiltrated cortex. CONCLUSION These findings inform our understanding of cognitive processing in patients with malignant gliomas and have implications for patient survival, neuromodulation, and prosthetics in patients with malignant gliomas.

Invasive electrophysiologic evaluation in octogenarians: Is age a limiting factor?

1993 ◽  
Vol 126 (5) ◽  
pp. 1142-1146 ◽  
Author(s):  
Alan B Wagshal ◽  
Claudio D Schuger ◽  
Bassam Habbal ◽  
Robert S Mittleman ◽  
Shoei K Stephen Huang
Keyword(s):  
Limiting Factor ◽  
Invasive Electrophysiologic

Invasive Electrophysiologic Studies in Children

1986 ◽  
Vol 4 (3) ◽  
pp. 551-563 ◽  
Author(s):  
Arthur Garson ◽  
Richard T. Smith ◽  
Jeffrey P. Moak
Keyword(s):  
Invasive Electrophysiologic ◽  
Electrophysiologic Studies

scholarly journals Usefulness of invasive electrophysiologic testing to stratify the risk of arrhythmic events in asymptomatic patients with Wolff-Parkinson-White pattern

2003 ◽  
Vol 41 (2) ◽  
pp. 239-244 ◽  
Author(s):  
Carlo Pappone ◽  
Vincenzo Santinelli ◽  
Salvatore Rosanio ◽  
Gabriele Vicedomini ◽  
Stefano Nardi ◽  
...  
Keyword(s):  
Electrophysiologic Testing ◽  
Asymptomatic Patients ◽  
Invasive Electrophysiologic
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