Long-Term Follow-Up of Isolated Epicardial Left Ventricular Lead Implant Using a Minithoracotomy Approach for Cardiac Resynchronization Therapy

2016 ◽  
Vol 39 (10) ◽  
pp. 1052-1060 ◽  
Author(s):  
CHRISTOPHER J. McALOON ◽  
BENJAMIN M. ANDERSON ◽  
WADIH DIMITRI ◽  
JONATHAN PANTING ◽  
SHAMIL YUSUF ◽  
...  
Keyword(s):  
Cardiac Resynchronization Therapy ◽  
Left Ventricular ◽  
Left Ventricular Lead ◽  
Cardiac Resynchronization ◽  
Resynchronization Therapy ◽  
Ventricular Lead ◽  
Long Term Follow Up

scholarly journals Left Ventricular Lead Location and Long-Term Outcomes in Cardiac Resynchronization Therapy Patients

2018 ◽  
Vol 4 (11) ◽  
pp. 1410-1420 ◽  
Author(s):  
Valentina Kutyifa ◽  
Annamaria Kosztin ◽  
Helmut U. Klein ◽  
Yitschak Biton ◽  
Vivien Klaudia Nagy ◽  
...  
Keyword(s):  
Cardiac Resynchronization Therapy ◽  
Left Ventricular ◽  
Left Ventricular Lead ◽  
Cardiac Resynchronization ◽  
Resynchronization Therapy ◽  
Long Term Outcomes ◽  
Ventricular Lead ◽  
Lead Location

scholarly journals Very Long-Term Follow-Up in Cardiac Resynchronization Therapy: Wider Paced QRS Equals Worse Prognosis

2021 ◽  
Vol 11 (11) ◽  
pp. 1176
Author(s):  
Patrick Leitz ◽  
Julia Köbe ◽  
Benjamin Rath ◽  
Florian Reinke ◽  
Gerrit Frommeyer ◽  
...  
Keyword(s):  
Cardiac Resynchronization Therapy ◽  
Clinical Response ◽  
Biventricular Pacing ◽  
Nyha Class ◽  
Left Ventricular ◽  
Cardiac Resynchronization ◽  
Resynchronization Therapy ◽  
Long Term Follow Up

Background: Different electrocardiogram (ECG) findings are known to be independent predictors of clinical response to cardiac resynchronization therapy (CRT). It remains unknown how these findings influence very long-term prognosis. Methods and Results: A total of 102 consecutive patients (75 males, mean age 65 ± 10 years) referred to our center for CRT implantation had previously been included in this prospective observational study. The same patient group was now re-evaluated for death from all causes over a prolonged median follow-up of 10.3 years (interquartile range 9.4–12.5 years). During follow-up, 55 patients died, and 82% of the clinical non-responders (n = 23) and 44% of the responders (n = 79) were deceased. We screened for univariate associations and found QRS width during biventricular (BIV) pacing (p = 0.02), left ventricular (LV) pacing (p < 0.01), Δ LV paced–right ventricular (RV) paced (p = 0.03), age (p = 0.03), New York Heart Association (NYHA) class (p < 0.01), CHA2DS2-Vasc score (p < 0.01), glomerular filtration rate (p < 0.01), coronary artery disease (p < 0.01), non-ischemic cardiomyopathy (NICM) (p = 0.01), arterial hypertension (p < 0.01), NT-proBNP (p < 0.01), and clinical response to CRT (p < 0.01) to be significantly associated with mortality. In the multivariate analysis, NICM, the lower NYHA class, and smaller QRS width during BIV pacing were independent predictors of better outcomes. Conclusion: Our data show that QRS width duration during biventricular pacing, an ECG parameter easily obtainable during LV lead placement, is an independent predictor of mortality in a long-term follow-up. Our data add further evidence that NICM and lower NYHA class are independent predictors for better outcome after CRT implantation.

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