scholarly journals Sternal Tumor Resection and Reconstruction with Titanium Mesh: a Preliminary Study

2015 ◽  
Vol 7 (2) ◽  
pp. 155-160 ◽  
Author(s):  
Yan Zhang ◽  
Jia-zhen Li ◽  
Ying-jie Hao ◽  
Xin-chang Lu ◽  
Hai-long Shi ◽  
...  
2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Kamel Alraei ◽  
Jameel Sharqawi ◽  
Somaya Harcher ◽  
Ibrahim Ghita

Recombinant human bone morphogenetic protein-2 (rhBMP-2) is an osteoinductive growth factor used in oral and maxillofacial surgery. It offers a feasible alternative for various regenerative procedures, including reconstruction of mandibular defects. In this study, we report a case of a large Pindborg tumor involving the left mandible. The treatment consisted of surgical resection, followed by off-label use of rhBMP-2 in addition to bone marrow aspirate concentrate, together with an allograft in a titanium mesh. The patient was rehabilitated with dental implants, and a good clinical outcome was achieved. We found no evidence of bone resorption or complications in both clinical and radiographic evaluations during the one-year follow-up period. In conclusion, we have demonstrated the efficacy of using rhBMP-2 combined with bone marrow aspirate concentrate, and an allograft with a titanium mesh, for the reconstruction of long mandibular bone defects. Not only is this combination feasible, but it also has the advantages of lower morbidity and cost.


2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Kyle D. Drinnon ◽  
Samir Sherali ◽  
Cameron T. Cox ◽  
Brendan J. MacKay

2016 ◽  
Vol 46 (1) ◽  
pp. 67-74 ◽  
Author(s):  
Desiree D. Rosselli ◽  
Simon R. Platt ◽  
Courtenay Freeman ◽  
Jeremy O'Neill ◽  
Marc Kent ◽  
...  

2018 ◽  
Vol 19 (1) ◽  
Author(s):  
Junqiang Yin ◽  
Hui Wu ◽  
Jian Tu ◽  
Changye Zou ◽  
Gang Huang ◽  
...  

Author(s):  
John H.L. Watson ◽  
John L. Swedo ◽  
R.W. Talley

A preliminary study of human mammary carcinoma on the ultrastructural level is reported for a metastatic, subcutaneous nodule, obtained as a surgical biopsy. The patient's tumor had responded favorably to a series of hormonal therapies, including androgens, estrogens, progestins, and corticoids for recurring nodules over eight years. The pertinent nodule was removed from the region of the gluteal maximus, two weeks following stilbestrol therapy. It was about 1.5 cms in diameter, and was located within the dermis. Pieces from it were fixed immediately in cold fixatives: phosphate buffered osmium tetroxide, glutaraldehyde, and paraformaldehyde. Embedment in each case was in Vestopal W. Contrasting was done with combinations of uranyl acetate and lead hydroxide.


Author(s):  
H.D. Geissinger ◽  
C.K. McDonald-Taylor

A new strain of mice, which had arisen by mutation from a dystrophic mouse colony was designated ‘mdx’, because the genetic defect, which manifests itself in brief periods of muscle destruction followed by episodes of muscle regeneration appears to be X-linked. Further studies of histopathological changes in muscle from ‘mdx’ mice at the light microscopic or electron microscopic levels have been published, but only one preliminary study has been on the tibialis anterior (TA) of ‘mdx’ mice less than four weeks old. Lesions in the ‘mdx’ mice vary between different muscles, and centronucleation of fibers in all muscles studied so far appears to be especially prominent in older mice. Lesions in young ‘mdx’ mice have not been studied extensively, and the results appear to be at variance with one another. The degenerative and regenerative aspects of the lesions in the TA of 23 to 26-day-old ‘mdx’ mice appear to vary quantitatively.


Author(s):  
J P Cassella ◽  
V Salih ◽  
T R Graham

Left ventricular assist systems are being developed for eventual long term or permanent implantation as an alternative to heart transplantation in patients unsuitable for or denied the transplant option. Evaluation of the effects of these devices upon normal physiology is required. A preliminary study was conducted to evaluate the morphology of aortic tissue from calves implanted with a pneumatic Left Ventricular Assist device-LVAD. Two 3 month old heifer calves (calf 1 and calf 2) were electively explanted after 128 days and 47 days respectively. Descending thoracic aortic tissue from both animals was removed immediately post mortem and placed into karnovsky’s fixative. The tissue was subsequently processed for transmission electron microscopy (TEM). Some aortic tissue was fixed in neutral buffered formalin and processed for routine light microscopy.


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