The effect of transcutaneous electrical nerve stimulation on increasing salivary flow rate in hemodialysis patients

Oral Diseases ◽  
2018 ◽  
Vol 25 (1) ◽  
pp. 133-141 ◽  
Author(s):  
Li‐Yu Yang ◽  
Hsing‐Mei Chen ◽  
Yi‐Ching Su ◽  
Chi‐Chun Chin
2015 ◽  
Vol 16 (6) ◽  
pp. 479-485 ◽  
Author(s):  
Neha Bhasin ◽  
Sreedevi Reddy ◽  
Anil Kumar Nagarajappa ◽  
Ankur Kakkad

ABSTRACT Background Saliva is a complex fluid, whose important role is to maintain the well being of oral cavity. Salivary gland hypofunction or hyposalivation is the condition of having reduced saliva production which leads to the subjective complaint of oral dryness termed xerostomia.7 Management of xerostomia includes palliative therapy using topical agents or systemic therapy. Electrostimulation to produce saliva was studied in the past and showed moderate promise but never became part of mainstream therapy. Hence, this study was undertaken to evaluate the effect of transcutaneous electrical nerve stimulation (TENS) on whole salivary flow rate in healthy adults and to evaluate how long this effect of TENS lasts on salivary flow. Materials and methods One hundred healthy adult subjects were divided into five age groups with each group containing 20 subjects equally divided into males and females in each group. Unstimulated saliva was collected using a graduated test tube fitted with funnel and quantity was measured. Transcutaneous electrical nerve stimulation unit was activated and stimulated saliva was collected. Saliva was again collected 30 minutes and 24 hours post stimulation. Results The mean unstimulated whole saliva flow rate for all subjects (n = 100) was 2.60 ml/5 min. During stimulation, it increased to 3.60 ± 0.39 ml/5 min. There was 38.46% increase in salivary flow. Ninety six out of 100 responded positively to TENS therapy. Salivary flow remained increased 30 minutes and 24 hours post stimulation with the values being 3.23 ± 0.41 ml/5 min and 2.69 ± 0.39 ml/5 min respectively. Repeated measures One way analysis of variance (ANOVA) test showed that the difference between these values were statistically significant. Conclusion Transcutaneous electrical nerve stimulation therapy was effective for stimulation of whole saliva in normal, healthy subjects and its effect retained till 30 minutes and a little up to 24 hours. Transcutaneous electrical nerve stimulation may work best synergistically with other sialagogues and can be used for the management of xerostomia. How to cite this article Bhasin N, Reddy S, Nagarajappa AK, Kakkad A. A Study on Duration of Effect of Transcutaneous Electrical Nerve Stimulation Therapy on Whole Saliva Flow. J Contemp Dent Pract 2015;16(6):479-485.


Nephron ◽  
2002 ◽  
Vol 91 (2) ◽  
pp. 210-214 ◽  
Author(s):  
Gulsen Bayraktar ◽  
Rumeyza Kazancioglu ◽  
Semra Bozfakioglu ◽  
Tevfik Ecder ◽  
Alaattin Yildiz ◽  
...  

Author(s):  
Farshad Teimoori ◽  
Mehrdad Hajilooei ◽  
Hamidreza Abdolsamadi ◽  
Khadijeh Eslami ◽  
Abbas Moghimbeigi ◽  
...  

Background: Helicobacter pylori infection identified as a major cause of stomach ulcers, chronic inflammation and gastric cancer in hemodialysis patients. Dialysis also leads to changes in the composition and flow of saliva. Objective: The aim of this study was to investigate the salivary Helicobacter pylori infection, Calcium, Urea, pH and flow rate in hemodialysis patients in comparison to the healthy control group. Method: In this study 48 hemodialysis patients and 48 healthy subjects were compared. The prevalence of Helicobacter pylori infection was determined by PCR method. Calcium, Urea, pH, salivary flow and gastrointestinal complications in both groups were measured and compared. Results: Prevalence of Helicobacter pylori was 12.48 (25.0%) in the study group and 2.48 (4.2%) in the controls. (P=0.000). Urea, calcium and pH were significantly higher in the patient group .The mean salivary flow rate decreased significantly in the patient group. 58.3% of patients group had gastrointestinal complications. Conclusion: Oral cavity as an important external source of Helicobacter pylori may play an important role in gastrointestinal problems of hemodialysis patients. Helicobacter pylori, Urea, calcium and pH were significantly higher in the patient group .Chronic renal failure can increase pH, urea and calcium in saliva and decrease salivary flow rate.


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