scholarly journals The complexity of oral physiology and its impact on salivary diagnostics

Oral Diseases ◽  
2017 ◽  
Vol 24 (3) ◽  
pp. 363-371 ◽  
Author(s):  
EJ Helmerhorst ◽  
C Dawes ◽  
FG Oppenheim
Keyword(s):  
Oral Physiology ◽  
Salivary Diagnostics

Nanoscale Characterisation of Salivary Pellicle

2004 ◽  
Vol 841 ◽  
Author(s):  
Michelle E. Dickinson ◽  
Adrian B. Mann
Keyword(s):  
Dental Enamel ◽  
Tooth Surface ◽  
Surface Adhesion ◽  
Human Enamel ◽  
Oral Physiology ◽  
Salivary Pellicle ◽  
Initial Adsorption ◽  
Dietary Agents

ABSTRACTSalivary pellicle is an organic biofilm formed by the physisorption of proteins and carbohydrates onto the surface of dental enamel exposed to the oral environment. The pellicle has several key roles in oral physiology including lubrication and reduction of friction between teeth during mastication, as well as chemical protection of the enamel against acidic solutions. However, pellicle proteins are known to react with dietary compounds to cause extrinsic staining on the tooth surface.In this study, nanoindentation and AFM have been used in vitro to examine the acquired salivary pellicle formed in vivo on dental enamel. The mechanical properties, growth, structure and morphology of pellicle grown in vivo on human enamel surfaces have been analysed. In addition, the effects of dietary agents such as polyphenols on the pellicle's morphology and properties have been studied.It was found that initial adsorption of proteins on the enamel surface occurred within 30 seconds of exposure to the oral cavity, with full growth achieved within 2 hours. Differences in the properties of the pellicles such as surface adhesion, and time dependent effects due to polyphenol interaction were measured using nanoindentation. It was seen that the polyphenol interaction has a significant effect on these properties. These results suggest that the stained pellicle is mechanically stiffer, but also less viscous and more fluid like. This could explain why traditional tooth brushing techniques do not efficiently remove this layer.

Salivary Diagnostics for Oral Cancer

2007 ◽  
Vol 2007 ◽  
pp. 137-138 ◽  
Author(s):  
J.M. Henderson
Keyword(s):  
Oral Cancer ◽  
Salivary Diagnostics

scholarly journals SALIVA AND SALIVAOMICS IN THE DIAGNOSIS OF ORAL AND SYSTEMIC DISEASES: A REVIEW

2021 ◽  
pp. 8-12
Author(s):  
Sherly Ruth ◽  
Koduri Sridevi ◽  
Buduru Krishnaveni ◽  
Nalli Prasanth Kumar ◽  
Katru Sreekar ◽  
...  
Keyword(s):  
Health Care ◽  
Early Detection ◽  
Patient Care ◽  
Disease Diagnosis ◽  
Response To Therapy ◽  
Response To Treatment ◽  
Systemic Diseases ◽  
Early Disease ◽  
Early Disease Detection ◽  
Salivary Diagnostics

The quest for novel strategies in early disease detection and response to therapy is an essential ongoing process in health care setups.Along with other body fluids such as blood,mucus,urine,semen and vaginal fluids;saliva can also be considered for the detection of the disease.The Salivary diagnostics is a dynamic field that is being incorporated as part of disease diagnosis, clinical monitoring and for making important clinical decisions for patient care. This review presents the translational value of saliva as a credible clinical diagnostic biofluid in detection, early detection of the various diseases and response to treatment.

scholarly journals Differences in metabolic profile between submandibular, parotid and whole saliva: a new concept in salivary diagnostics.

2019 ◽  
Vol 10 ◽  
Author(s):  
Rita Antonelli ◽  
Thelma Pertinhez ◽  
Margherita Eleonora Pezzi ◽  
Benedetta Ghezzi ◽  
Paolo Vescovi ◽  
...  
Keyword(s):  
Metabolic Profile ◽  
Whole Saliva ◽  
Salivary Diagnostics
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