scholarly journals Obesity and endocrine therapy resistance in breast cancer: Mechanistic insights and perspectives

2021 ◽  
Author(s):  
Ines Barone ◽  
Amanda Caruso ◽  
Luca Gelsomino ◽  
Cinzia Giordano ◽  
Daniela Bonofiglio ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Endocrine Therapy ◽  
Therapy Resistance ◽  
Endocrine Therapy Resistance

scholarly journals Long Noncoding RNAs Involved in the Endocrine Therapy Resistance of Breast Cancer

Cancers ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1424 ◽  
Author(s):  
Toshihiko Takeiwa ◽  
Kazuhiro Ikeda ◽  
Yuichi Mitobe ◽  
Kuniko Horie-Inoue ◽  
Satoshi Inoue
Keyword(s):  
Breast Cancer ◽  
Endocrine Therapy ◽  
Noncoding Rnas ◽  
Therapeutic Targets ◽  
Therapy Resistance ◽  
Long Noncoding Rnas ◽  
Endocrine Therapy Resistance ◽  
New Biomarkers

Long noncoding RNAs (lncRNAs) are defined as RNAs longer than 200 nucleotides that do not encode proteins. Recent studies have demonstrated that numerous lncRNAs are expressed in humans and play key roles in the development of various types of cancers. Intriguingly, some lncRNAs have been demonstrated to be involved in endocrine therapy resistance for breast cancer through their own mechanisms, suggesting that lncRNAs could be promising new biomarkers and therapeutic targets of breast cancer. Here, we summarize the functions and mechanisms of lncRNAs related to the endocrine therapy resistance of breast cancer.

scholarly journals Loss of MutL Disrupts CHK2-Dependent Cell-Cycle Control through CDK4/6 to Promote Intrinsic Endocrine Therapy Resistance in Primary Breast Cancer

2017 ◽  
Vol 7 (10) ◽  
pp. 1168-1183 ◽  
Author(s):  
Svasti Haricharan ◽  
Nindo Punturi ◽  
Purba Singh ◽  
Kimberly R. Holloway ◽  
Meenakshi Anurag ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Cycle ◽  
Endocrine Therapy ◽  
Primary Breast Cancer ◽  
Cell Cycle Control ◽  
Therapy Resistance ◽  
Endocrine Therapy Resistance ◽  
Dependent Cell

scholarly journals Comprehensive Profiling of DNA Repair Defects in Breast Cancer Identifies a Novel Class of Endocrine Therapy Resistance Drivers

2018 ◽  
Vol 24 (19) ◽  
pp. 4887-4899 ◽  
Author(s):  
Meenakshi Anurag ◽  
Nindo Punturi ◽  
Jeremy Hoog ◽  
Matthew N. Bainbridge ◽  
Matthew J. Ellis ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Dna Repair ◽  
Endocrine Therapy ◽  
Therapy Resistance ◽  
Endocrine Therapy Resistance

scholarly journals Candidate methylation sites associated with endocrine therapy resistance in ER+/HER2- breast cancer

BMC Cancer ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Maryam Soleimani Dodaran ◽  
Simone Borgoni ◽  
Emre Sofyalı ◽  
Pernette J. Verschure ◽  
Stefan Wiemann ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Endocrine Therapy ◽  
Therapy Resistance ◽  
Endocrine Therapy Resistance ◽  
Her2 Breast Cancer
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