scholarly journals Clinical effectiveness of very-low-energy diets in the management of weight loss: a systematic review and meta-analysis of randomized controlled trials

2016 ◽  
Vol 17 (3) ◽  
pp. 225-234 ◽  
Author(s):  
H. M. Parretti ◽  
S. A. Jebb ◽  
D. J. Johns ◽  
A. L. Lewis ◽  
A. M. Christian-Brown ◽  
...  
Keyword(s):  
Systematic Review ◽  
Weight Loss ◽  
Randomized Controlled Trials ◽  
Meta Analysis ◽  
Clinical Effectiveness ◽  
Low Energy ◽  
Controlled Trials ◽  
Randomized Controlled

Efficacy of First-Time Intragastric Balloon in Weight Loss: a Systematic Review and Meta-analysis of Randomized Controlled Trials

2016 ◽  
Vol 27 (2) ◽  
pp. 277-287 ◽  
Author(s):  
Alan A. Saber ◽  
Saeed Shoar ◽  
Mahmoud W. Almadani ◽  
Natan Zundel ◽  
Mohammed J. Alkuwari ◽  
...  
Keyword(s):  
Systematic Review ◽  
Weight Loss ◽  
Randomized Controlled Trials ◽  
Intragastric Balloon ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
First Time

scholarly journals Acute glycemic and insulinemic effects of low-energy sweeteners: a systematic review and meta-analysis of randomized controlled trials

2020 ◽  
Vol 112 (4) ◽  
pp. 1002-1014 ◽  
Author(s):  
Arno Greyling ◽  
Katherine M Appleton ◽  
Anne Raben ◽  
David J Mela
Keyword(s):  
Systematic Review ◽  
Type 2 Diabetes ◽  
Randomized Controlled Trials ◽  
Fasting Glucose ◽  
Meta Analysis ◽  
Low Energy ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
The Mean

ABSTRACT Background It has been suggested that low-energy sweeteners (LES) may be associated with an increased risk of metabolic diseases, possibly due to stimulation of glucose-responsive mechanisms. Objective We conducted a systematic review and meta-analysis of human intervention studies examining the acute effect of LES intake on postprandial glucose (PPG) and postprandial insulin (PPI) responses, in order to comprehensively and objectively quantify these relations. Methods We systematically searched the Medline, OVID FSTA, and SCOPUS databases until January 2020. Randomized controlled trials comparing acute postprandial effects on PPG and/or PPI after exposure to LES, either alone, with a meal, or with other nutrient-containing preloads to the same intervention without LES were eligible for inclusion. PPG and PPI responses were calculated as mean incremental area under the curve divided by time. Meta-analyses were performed using random effects models with inverse variance weighing. Results Twenty-six papers (34 PPG trials and 29 PPI trials) were included. There were no reports of statistically significant differences in the effects of LES on PPG and PPI responses compared with control interventions. Pooled effects of LES intake on the mean change difference in PPG and PPI were −0.02 mmol/L (95% CI: −0.09, 0.05) and −2.39 pmol/L (95% CI: −11.83, 7.05), respectively. The results did not appreciably differ by the type or dose of LES consumed, cointervention type, or fasting glucose and insulin levels. Among patients with type 2 diabetes, the mean change difference indicated a smaller PPG response after exposure to LES compared with the control (−0.3 mmol/L; 95% CI: −0.53, −0.07). Conclusions Ingestion of LES, administered alone or in combination with a nutrient-containing preload, has no acute effects on the mean change in postprandial glycemic or insulinemic responses compared with a control intervention. Apart from a small beneficial effect on PPG (−0.3 mmol/L) in studies enrolling patients with type 2 diabetes, the effects did not differ by type or dose of LES, or fasting glucose or insulin levels. This review and meta-analysis was registered at PROSPERO as CRD42018099608.

scholarly journals Isolated Aerobic Exercise and Weight Loss: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

2011 ◽  
Vol 124 (8) ◽  
pp. 747-755 ◽  
Author(s):  
Adrian Thorogood ◽  
Salvatore Mottillo ◽  
Avi Shimony ◽  
Kristian B. Filion ◽  
Lawrence Joseph ◽  
...  
Keyword(s):  
Systematic Review ◽  
Weight Loss ◽  
Aerobic Exercise ◽  
Randomized Controlled Trials ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Randomized Controlled
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