Long-chain polyunsaturated fatty acid status in obesity: a systematic review and meta-analysis

2015 ◽  
Vol 16 (6) ◽  
pp. 488-497 ◽  
Author(s):  
K. Fekete ◽  
E. Györei ◽  
S. Lohner ◽  
E. Verduci ◽  
C. Agostoni ◽  
...  
Keyword(s):  
Systematic Review ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acid ◽  
Meta Analysis ◽  
Chain Polyunsaturated Fatty Acid ◽  
Fatty Acid Status ◽  
Acid Status ◽  
Long Chain

The effects of low-ratio n-6/n-3 PUFA on biomarkers of inflammation: a systematic review and meta-analysis

2021 ◽  
Author(s):  
Yali Wei ◽  
Yan Meng ◽  
Na Li ◽  
Qian Wang ◽  
Liyong Chen
Keyword(s):  
Systematic Review ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acid ◽  
Meta Analysis ◽  
Chain Polyunsaturated Fatty Acid ◽  
Inflammation Markers ◽  
Pufa Supplementation ◽  
Long Chain

The purpose of the systematic review and meta-analysis was to determine if low-ratio n-6/n-3 long-chain polyunsaturated fatty acid (PUFA) supplementation affects serum inflammation markers based on current studies.

Effects of Liver Transplantation on Long-Chain Polyunsaturated Fatty Acid Status in Infants with Biliary Atresia

2000 ◽  
Vol 30 (5) ◽  
pp. 528-532 ◽  
Author(s):  
Alexandre Lapillonne ◽  
Christine Hakme ◽  
Valérie Mamoux ◽  
Michelle Chambon ◽  
Vincent Fournier ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Fatty Acid ◽  
Biliary Atresia ◽  
Polyunsaturated Fatty Acid ◽  
Chain Polyunsaturated Fatty Acid ◽  
Fatty Acid Status ◽  
Acid Status ◽  
Long Chain

scholarly journals Maternal long chain polyunsaturated fatty acid status is associated with child growth

2013 ◽  
Vol 72 (OCE2) ◽  
Author(s):  
M. S. Mulhern ◽  
A. Yeates ◽  
E. M. McSorley ◽  
J. M. W. Wallace ◽  
G. J. Myers ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Polyunsaturated Fatty Acid ◽  
Child Growth ◽  
Chain Polyunsaturated Fatty Acid ◽  
Fatty Acid Status ◽  
Acid Status ◽  
Long Chain

scholarly journals Adjunct n-3 Long-Chain Polyunsaturated Fatty Acid Treatment in Tuberculosis Reduces Inflammation and Improves Anemia of Infection More in C3HeB/FeJ Mice With Low n-3 Fatty Acid Status Than Sufficient n-3 Fatty Acid Status

2021 ◽  
Vol 8 ◽  
Author(s):  
Frank E. A. Hayford ◽  
Robin C. Dolman ◽  
Mumin Ozturk ◽  
Arista Nienaber ◽  
Cristian Ricci ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Polyunsaturated Fatty Acid ◽  
Post Infection ◽  
Lipid Mediators ◽  
Chain Polyunsaturated Fatty Acid ◽  
Lung Pathology ◽  
Fatty Acid Status ◽  
Populations At Risk ◽  
Acid Status ◽  
Long Chain

Populations at risk for tuberculosis (TB) may have a low n-3 polyunsaturated fatty acid (PUFA) status. Our research previously showed that post-infection supplementation of n-3 long-chain PUFA (LCPUFA) in TB without TB medication was beneficial in n-3 PUFA sufficient but not in low-status C3HeB/FeJ mice. In this study, we investigated the effect of n-3 LCPUFA adjunct to TB medication in TB mice with a low compared to a sufficient n-3 PUFA status. Mice were conditioned on an n-3 PUFA-deficient (n-3FAD) or n-3 PUFA-sufficient (n-3FAS) diet for 6 weeks before TB infection. Post-infection at 2 weeks, both groups were switched to an n-3 LCPUFA [eicosapentaenoic acid (EPA)/docosahexaenoic acid (DHA)] supplemented diet and euthanized at 4- and 14- days post-treatment. Iron and anemia status, bacterial loads, lung pathology, lung cytokines/chemokines, and lung lipid mediators were measured. Following 14 days of treatment, hemoglobin (Hb) was higher in the n-3FAD than the untreated n-3FAS group (p = 0.022), whereas the n-3FAS (drug) treated control and n-3FAS groups were not. Pro-inflammatory lung cytokines; interleukin-6 (IL-6) (p = 0.011), IL-1α (p = 0.039), MCP1 (p = 0.003), MIP1- α (p = 0.043), and RANTES (p = 0.034); were lower, and the anti-inflammatory cytokine IL-4 (p = 0.002) and growth factor GMCSF (p = 0.007) were higher in the n-3FAD compared with the n-3FAS mice after 14 days. These results suggest that n-3 LCPUFA therapy in TB-infected mice, in combination with TB medication, may improve anemia of infection more in low n-3 fatty acid status than sufficient status mice. Furthermore, the low n-3 fatty acid status TB mice supplemented with n-3 LCPUFA showed comparatively lower cytokine-mediated inflammation despite presenting with lower pro-resolving lipid mediators.

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