Quantitative relationship between body weight gain in adulthood and incident type 2 diabetes: a meta-analysis

2013 ◽  
Vol 15 (3) ◽  
pp. 202-214 ◽  
Author(s):  
S. Kodama ◽  
C. Horikawa ◽  
K. Fujihara ◽  
S. Yoshizawa ◽  
Y. Yachi ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Body Weight ◽  
Weight Gain ◽  
Body Weight Gain ◽  
Meta Analysis ◽  
Quantitative Relationship ◽  
Incident Type ◽  
Incident Type 2 Diabetes

scholarly journals Relation of total sugars, fructose and sucrose with incident type 2 diabetes: a systematic review and meta-analysis of prospective cohort studies

2017 ◽  
Vol 189 (20) ◽  
pp. E711-E720 ◽  
Author(s):  
Christine S. Tsilas ◽  
Russell J. de Souza ◽  
Sonia Blanco Mejia ◽  
Arash Mirrahimi ◽  
Adrian I. Cozma ◽  
...  
Keyword(s):  
Systematic Review ◽  
Type 2 Diabetes ◽  
Cohort Studies ◽  
Prospective Cohort ◽  
Meta Analysis ◽  
Total Sugars ◽  
Incident Type ◽  
Prospective Cohort Studies ◽  
Incident Type 2 Diabetes

The association between GAD65 antibody levels and incident Type 2 Diabetes Mellitus in an adult population: A meta-analysis

Metabolism ◽  
2019 ◽  
Vol 95 ◽  
pp. 1-7 ◽  
Author(s):  
Anitra D.M. Koopman ◽  
Joline W. Beulens ◽  
Ellis Voerman ◽  
Simone P. Rauh ◽  
Amber A. van der Heijden ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Meta Analysis ◽  
Adult Population ◽  
Incident Type ◽  
Incident Type 2 Diabetes ◽  
Gad65 Antibody ◽  
Antibody Levels

scholarly journals Chromium Picolinate Supplementation Attenuates Body Weight Gain and Increases Insulin Sensitivity in Subjects With Type 2 Diabetes

Diabetes Care ◽  
2006 ◽  
Vol 29 (8) ◽  
pp. 1826-1832 ◽  
Author(s):  
J. Martin ◽  
Z. Q. Wang ◽  
X. H. Zhang ◽  
D. Wachtel ◽  
J. Volaufova ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Body Weight ◽  
Weight Gain ◽  
Insulin Sensitivity ◽  
Body Weight Gain ◽  
Chromium Picolinate

scholarly journals I-M-150847, a novel GLP-1 and GIP receptor dual agonist, reduces body weight gain and improves glycemic control in the rodent model of type 2 diabetes and obesity.

2021 ◽  
Author(s):  
PRASENJIT MITRA ◽  
Rathin Bauri ◽  
Shilpak Bele ◽  
Jhansi Edelli ◽  
Sourav Dasadhikari ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Body Weight ◽  
Weight Gain ◽  
Body Weight Gain ◽  
Single Amino Acid ◽  
The Novel ◽  
Diabetes And Obesity ◽  
Dual Agonist ◽  
Gip Receptor

We report the discovery of a novel glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor dual agonist that shows balanced agonism towards both the incretin receptor. The dual agonism of GLP-1 and GIP receptor was achieved by replacing the tryptophan cage of exendin-4 with the C- terminal undecapeptide sequence of oxyntomodulin along with a single amino acid substitution from histidine to tyrosine at the amino terminus of the peptide. The structural modification places lysine 30 of the novel incretin agonist in frame with the corresponding lysine residue in the native GIP sequence. The novel incretin agonist, named I-M-150847, promotes robust glucose-stimulated insulin exocytosis in cultured pancreatic beta cells. Chronic administration of I-M-150847 to mice fed on the high-fat diet improves glucose tolerance, decreases food intake, decreases visceral adiposity and body weight gain demonstrating its therapeutic potential in ameliorating type 2 Diabetes and Obesity.

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