Double‐checking esophageal function tests. Comment on: Carlson et al. evaluating esophageal motility beyond primary peristalsis: assessing esophagogastric junction opening mechanics and secondary peristalsis in patients with normal manometry

2021 ◽  
Author(s):  
Fernando A. M. Herbella ◽  
Marco G. Patti
Keyword(s):  
Esophageal Motility ◽  
Esophagogastric Junction ◽  
Esophageal Function ◽  
Primary Peristalsis ◽  
Function Tests ◽  
Secondary Peristalsis

Effect of thoracic vagotomy and vagal stimulation on esophageal function.

1978 ◽  
Vol 234 (4) ◽  
pp. E359 ◽  
Author(s):  
J J Kravitz ◽  
W J Snape ◽  
S Cohen
Keyword(s):  
Electrical Stimulation ◽  
Vagal Stimulation ◽  
Esophageal Function ◽  
Primary Peristalsis ◽  
Vagal Innervation ◽  
Relaxation Responses ◽  
Secondary Peristalsis ◽  
Thoracic Vagotomy ◽  
Upper Thoracic ◽  
Stimulation Of

The purpose of this study was to determine the effect of thoracic vagotomy and thoracic vagal stimulation upon esophageal peristalsis and lower esophageal sphincter (LES) function in the opossum. The thoracic portion of the vagus nerve was sectioned in the upper or lower thorax. Bilateral, but not unilateral, thoracic vagotomy above the level of the heart abolished peristalsis and LES relaxation in response to swallowing or cervical vagal electrical stimulation. Thoracic vagotomy at the level of the ventricle or below did not alter either peristalsis or LES relaxation during swallowing or cervical vagal stimulation. Secondary peristalsis and its associated LES relaxation was unaltered by thoracic vagotomy at any level. Electrical stimulation of the distal end of the upper thoracic vagus elicited both peristalsis and LES relaxation. Electrical stimulation of the distal end of the lower thoracic vagus elicited both peristalsis and LES relaxation. Electrical stimulation of the distal end of the lower thoracic vagus, as well as stimulation of the vagal branches to the terminal esophagus, gave only LES relaxation. These studies suggest that: a) the major extrinsic vagal innervation mediating primary peristalsis terminates in the upper portion of the esophagus, whereas the vagal innervation mediating LES relaxation responses are present throughout the length of the esophagus; and b) secondary peristalsis and its associated LES relaxation occurs independent of extrinsic vagal innervation.

Esophagus in rumination

1964 ◽  
Vol 207 (6) ◽  
pp. 1189-1194 ◽  
Author(s):  
Daniel H. Winship ◽  
F. Frank Zboralske ◽  
William N. Weber ◽  
Konrad H. Soergel
Keyword(s):  
Pressure Difference ◽  
Esophageal Motility ◽  
Motor Response ◽  
Initial Pressure ◽  
Primary Peristalsis ◽  
Balloon Distention ◽  
Esophageal Sphincter ◽  
Secondary Peristalsis ◽  
Contraction Wave ◽  
Pressure Plateau

Esophageal motility studies of deglutition and rumination were performed in two sheep, two goats, and one calf. The esophageal motor response to balloon distention was investigated in the two sheep. Deglutition and rumination were studied cinefluorographically in the two sheep and one goat. All animals had a ruminoesophageal pressure difference of from 3 to 8 mm Hg, but none exhibited an inferior esophageal sphincter. Primary peristalsis progressed at a rate of 23.5–27.5 cm/sec. Secondary peristalsis was present only in the distal 10 cm of the esophagus, and only distal to the distending balloon. Rumination, unrelated to respiration, produced an initial pressure plateau interpreted as ruminoesophageal reflux, terminating in a contraction wave which was frequently of retrograde peristaltic character in the sheep and calf, traveling at rates averaging 42.5 and 53.8 cm/ sec in the sheep, 112.5 cm/sec in the calf. Rumination begins with ruminoesophageal reflux, facilitated by the ruminoesophageal pressure difference and absence of the inferior esophageal sphincter. The bolus is frequently carried toward the mouth by retrograde peristalsis.

Comparison of primary and secondary esophageal peristalsis in humans: effect of atropine

1991 ◽  
Vol 260 (1) ◽  
pp. G52-G57 ◽  
Author(s):  
W. G. Paterson ◽  
T. T. Hynna-Liepert ◽  
M. Selucky
Keyword(s):  
Neural Pathways ◽  
Esophageal Peristalsis ◽  
Healthy Male ◽  
Double Blind ◽  
Primary Peristalsis ◽  
Lower Amplitude ◽  
Catheter System ◽  
The Subject ◽  
Esophageal Sphincter ◽  
Secondary Peristalsis

To determine whether physiological differences exist between primary (swallow-induced) and secondary (distension-induced) peristalsis in humans, 10 healthy male volunteers underwent esophageal manometry on 2 consecutive days using a perfused intraluminal catheter system that incorporated a latex balloon. Initially the catheter was positioned so that the balloon was centered 16 cm above the lower esophageal sphincter (LES), and intraluminal pressures were recorded 21, 11, 6, and 1 cm above the LES. After a series of wet swallows, dry swallows, and balloon distensions, the catheter was repositioned so that the balloon was 6 cm above the LES and pressures were recorded 1 and 11 cm above the LES. A series of balloon distensions were repeated in this position, and the subject was then given either atropine (10 micrograms/kg iv) or placebo in a double-blind randomized fashion (on consecutive days). The protocol was then repeated in reverse order. Distension-induced responses aboral to the balloon with the balloon located 16 cm above the LES were 1) of lower amplitude, 2) more often nonperistaltic, and 3) less atropine sensitive than swallow-induced contractions at comparable sites. With the balloon located distally (6 cm above LES) contractions induced at the 11-cm site (i.e., orad to the balloon) were much more atropine sensitive than contractions induced at the same site when the balloon was located proximally (i.e., 16 cm above LES). These data suggest that, contrary to previous reports, secondary peristalsis differs significantly from primary peristalsis. Furthermore, atropine differentially effects these two types of peristalsis, suggesting that the neural pathways involved are dissimilar.

Esophageal Function Tests

2011 ◽  
pp. 1-14
Author(s):  
Vinay Chandrasekhara ◽  
Sanjay Jagannath
Keyword(s):  
Esophageal Function ◽  
Function Tests

scholarly journals Correction to: Esophageal Function Tests are Not Associated with Barium Swallow Findings in Advanced Lung Disease

Dysphagia ◽  
2020 ◽  
Vol 35 (5) ◽  
pp. 871-871
Author(s):  
Shai Posner ◽  
Kurren Mehta ◽  
Alice Parish ◽  
Donna Niedzwiecki ◽  
Rajan T. Gupta ◽  
...  
Keyword(s):  
Lung Disease ◽  
Barium Swallow ◽  
Esophageal Function ◽  
Function Tests

Combined Manometric-pH Recording Catheter for Esophageal Function Tests

1978 ◽  
Vol 26 (6) ◽  
pp. 581-585 ◽  
Author(s):  
Mark B. Orringer ◽  
Robert Lee ◽  
Herbert Sloan
Keyword(s):  
Esophageal Function ◽  
Function Tests

Tu1412 IMPACT OF INEFFECTIVE ESOPHAGEAL MOTILITY ON SECONDARY PERISTALSIS IN GERD: STUDIES WITH HIGH RESOLUTION MANOMETRY

2020 ◽  
Vol 158 (6) ◽  
pp. S-1095-S-1096
Author(s):  
Wei-Yi Lei ◽  
Jen-Hung Wang ◽  
Ming-Wun Wong ◽  
Chih-Hsun Yi ◽  
Tso-Tsai Liu ◽  
...  
Keyword(s):  
High Resolution ◽  
Esophageal Motility ◽  
High Resolution Manometry ◽  
Ineffective Esophageal Motility ◽  
Secondary Peristalsis
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