scholarly journals Effect of amino acid‐based formula added to four‐food elimination in adult eosinophilic esophagitis patients: A randomized clinical trial

2021 ◽  
Author(s):  
Willemijn E. de Rooij ◽  
Berber Vlieg – Boerstra ◽  
Marijn J. Warners ◽  
Marleen T.J. Van Ampting ◽  
Betty C. A. M. van Esch ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Amino Acid ◽  
Randomized Clinical Trial ◽  
Eosinophilic Esophagitis ◽  
Food Elimination

727 A Prospective Clinical Trial of Six Food Elimination Diet and Reintroduction of Causative Agents in Adults with Eosinophilic Esophagitis (EE)

2008 ◽  
Vol 134 (4) ◽  
pp. A-104-A-105 ◽  
Author(s):  
Nirmala Gonsalves ◽  
Guang-Yu Yang ◽  
Bethany Doerfler ◽  
Sally Ritz ◽  
Anne M. Ditto ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Eosinophilic Esophagitis ◽  
Elimination Diet ◽  
Prospective Clinical Trial ◽  
Causative Agents ◽  
Food Elimination

Short ultrasonic debridement with adjunctive low-concentrated hypochlorite/amino acid gel during periodontal maintenance: randomized clinical trial of 12 months

2019 ◽  
Vol 24 (1) ◽  
pp. 201-209 ◽  
Author(s):  
Andrew Megally ◽  
Alkisti Zekeridou ◽  
José Cancela ◽  
Catherine Giannopoulou ◽  
Andrea Mombelli
Keyword(s):  
Clinical Trial ◽  
Amino Acid ◽  
Randomized Clinical Trial ◽  
Acid Gel ◽  
Periodontal Maintenance

A Randomized Clinical Trial with a 0.6% Amino Acid/1.4% Glycerol Peritoneal Dialysis Solution

2004 ◽  
Vol 24 (3) ◽  
pp. 222-230 ◽  
Author(s):  
Wim Van Biesen ◽  
Walter Boer ◽  
Bart De Greve ◽  
Clement Dequidt ◽  
Denise Vijt ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Peritoneal Dialysis ◽  
Amino Acid ◽  
Randomized Clinical Trial ◽  
Glucose Solution ◽  
Test Group ◽  
Test Solution ◽  
Control Group ◽  
Glycerol Solution ◽  
Dialysis Solution

Background Glucose is an accepted osmotic agent for peritoneal dialysis (PD) although it has several drawbacks. Some of these drawbacks have been addressed by the introduction of solutions with low glucose degradation products and physiological pH in dual-chambered bags. Despite this achievement, there is a need for alternative osmotic agents. This randomized clinical trial analyzes 3-month's clinical experience with a mixture of 0.6% amino acids and 1.4% glycerol. Methods The study was performed at the renal units of the University Hospitals Ghent, Belgium, and Utrecht, The Netherlands. Stable PD patients were randomized for either protocol A (test solution, n = 5) or protocol B (control regimen, n = 5). In both protocols, there was a run-in phase of 1 month with a dialysis regimen of 2 × 2 L 2.27% glucose solution (Dianeal; Baxter, Nivelles, Belgium), 1 × 2 L Extraneal (Baxter), and 1 × 2 L glucose solution (Dianeal). After this month-long run-in period, patients in group A received during 3 months 2 × 2 L amino acid/glycerol solution, 1 × 2 L Extraneal, and at least 1 × 2 L of a classic glucose solution. Results Glucose absorption decreased in the test group during the test phase (from 84.2 ± 8.7 to 11.7 ± 11.6 g/24 hours, p = 0.001). Dialysate levels of cancer antigen 125 (CA125) increased in the test group, from 17.5 ± 11.0 to 32.4 ± 4.6 units/L ( p = 0.04), whereas, in the control group, the levels remained stable (15.5 ± 8.7 and 14.9 ± 9.8 units/L respectively, p = 0.4). There were no differences in serum urea, serum bicarbonate, serum osmolarity, serum albumin, or parameters related to skin-fold thickness or serum glycerol levels between control and test solutions. No differences were observed in obtained ultrafiltration after a 4-hour dwell with 2.27% glucose or the test solution, both measured at week 4 of the run-in period and week 12 of the test period. Conclusion This study demonstrated that the use of a new 0.6% amino acid/1.4% glycerol-containing dialysis solution is safe and well tolerated. Glucose load was reduced significantly and dialysate CA125 levels improved significantly. Ultrafiltration was comparable with that of a 2.27% glucose solution. All these factors, in combination with the potential nutritional benefits, can contribute to a beneficial impact on the success of the PD technique. Further long-term studies in larger patient groups are warranted to explore the potential of this promising new solution.

Randomized clinical trial of LigasureTM versus open haemorrhoidectomy

2002 ◽  
Vol 89 (2) ◽  
pp. 154-157 ◽  
Author(s):  
F. F Palazzo ◽  
D. L Francis ◽  
M. A Clifton
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial
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