Enhancing the utility of antroduodenal manometry in pediatric intestinal pseudo‐obstruction

2021 ◽  
Author(s):  
Atchariya Chanpong ◽  
Hannah Cronin ◽  
Dyanne Rampling ◽  
Michael Ashworth ◽  
Simon Eaton ◽  
...  
Keyword(s):  
Antroduodenal Manometry ◽  
Intestinal Pseudo Obstruction

scholarly journals Chronic intestinal pseudo-obstruction in systemic lupus erythematosus

Gut ◽  
1998 ◽  
Vol 43 (1) ◽  
pp. 117-122 ◽  
Author(s):  
G Perlemuter ◽  
S Chaussade ◽  
B Wechsler ◽  
P Cacoub ◽  
M Dapoigny ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Smooth Muscle ◽  
Lupus Erythematosus ◽  
Bladder Capacity ◽  
High Dose ◽  
Systemic Lupus ◽  
Muscle Involvement ◽  
Antroduodenal Manometry ◽  
Intestinal Pseudo Obstruction ◽  
Visceral Smooth Muscle

Background/Aims—Chronic intestinal pseudo-obstruction (CIPO) reflects a dysfunction of the visceral smooth muscle or the enteric nervous system. Gastrointestinal manifestations are common in systemic lupus erythematosus (SLE) but CIPO has not been reported. Features of CIPO are reported in five patients with SLE.Methods—From 1988 to 1993, five patients with SLE or SLE-like syndrome were hospitalised for gastrointestinal manometric studies. CIPO was the onset feature in two cases. Antroduodenal manometry (three hours fasting, two hours fed) was performed in all patients, and oesophageal manometry in four.Results—Intestinal hypomotility associated with reduced bladder capacity and bilateral ureteral distension was found in four patients and aperistalsis of the oesophagus in three. Treatment, which consisted of high dose corticosteroids, parenteral nutrition, promotility agents, and antibiotics, led to remission of both CIPO and urinary abnormalities in all cases. Antroduodenal manometry performed in two patients after remission showed increased intestinal motility. One patient died, and postmortem examination showed intestinal vasculitis.Conclusions—CIPO in SLE is a life threatening situation that can be reversed by treatment. It may be: (a) a complication or onset feature of the disease; (b) secondary to smooth muscle involvement; (c) associated with ureteral and vesical involvement; (d) the result of intestinal vasculitis.

scholarly journals Etiology and Management of Pediatric Intestinal Failure: Focus on the Non-Digestive Causes

Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 786
Author(s):  
Antonella Diamanti ◽  
Giacomo Calvitti ◽  
Diego Martinelli ◽  
Emma Santariga ◽  
Teresa Capriati ◽  
...  
Keyword(s):  
Parenteral Nutrition ◽  
Intestinal Failure ◽  
Present Review ◽  
Special Focus ◽  
Minimal Amount ◽  
Pathophysiological Mechanisms ◽  
Liver And Pancreas ◽  
Comprehensive Search ◽  
Therapeutic Tools ◽  
Intestinal Pseudo Obstruction

Background: Intestinal failure (IF) is defined as reduction in functioning gut mass below the minimal amount necessary for adequate digestion and absorption. In most cases, IF results from intrinsic diseases of the gastrointestinal tract (digestive IF) (DIF); few cases arise from digestive vascular components, gut annexed (liver and pancreas) and extra-digestive organs or from systemic diseases (non-digestive IF) (NDIF). The present review revised etiology and treatments of DIF and NDIF, with special focus on the pathophysiological mechanisms, whereby NDIF develops. Methods: We performed a comprehensive search of published literature from January 2010 to the present by selecting the following search strings: “intestinal failure” OR “home parenteral nutrition” OR “short bowel syndrome” OR “chronic pseudo-obstruction” OR “chronic intestinal pseudo-obstruction” OR “autoimmune enteropathy” OR “long-term parenteral nutrition”. Results: We collected overall 1656 patients with well-documented etiology of IF: 1419 with DIF (86%) and 237 with NDIF (14%), 55% males and 45% females. Among DIF cases, 66% had SBS and among NDIF cases 90% had malabsorption/maldigestion. Conclusions: The improved availability of diagnostic and therapeutic tools has increased prevalence and life expectancy of rare and severe diseases responsible for IF. The present review greatly expands the spectrum of knowledge on the pathophysiological mechanisms through which the diseases not strictly affecting the intestine can cause IF. In view of the rarity of the majority of pediatric IF diseases, the development of IF Registries is strongly required; in fact, through information flow within the network, the Registries could improve IF knowledge and management.

Effects of erythromycin in chronic idiopathic intestinal pseudo-obstruction

1996 ◽  
Vol 31 (6) ◽  
pp. 855-859 ◽  
Author(s):  
Takeshi Minami ◽  
Hiroyuki Nishibayashi ◽  
Yasuhisa Shinomura ◽  
Yuji Matsuzawa
Keyword(s):  
Intestinal Pseudo Obstruction

Pheochromocytoma presented as intestinal pseudo-obstruction and hyperamylasemia

2008 ◽  
Vol 26 (8) ◽  
pp. 971.e1-971.e4 ◽  
Author(s):  
Hsi-Wen Wu ◽  
Wen-Ping Liou ◽  
Chih-Chieh Chou ◽  
Yeong-Hwang Chen ◽  
Ching-Hui Loh ◽  
...  
Keyword(s):  
Intestinal Pseudo Obstruction

Kawasaki Disease Presenting with Intestinal Pseudo-Obstruction

2020 ◽  
Vol 87 (7) ◽  
pp. 569-570 ◽  
Author(s):  
Pediredla Karunakar ◽  
Dhandapany Gunasekaran ◽  
Jaikumar Govindaswamy Ramamoorthy ◽  
Sriram Krishnamurthy ◽  
Avinash Anantharaj ◽  
...  
Keyword(s):  
Kawasaki Disease ◽  
Intestinal Pseudo Obstruction

Analysis of candidate genes for intrinsic neuropathy in a family with chronic idiopathic intestinal pseudo-obstruction

2001 ◽  
Vol 59 (2) ◽  
pp. 131-133 ◽  
Author(s):  
R De Giorgio ◽  
M Seri ◽  
RF Cogliandro ◽  
R Cusano ◽  
M Fava ◽  
...  
Keyword(s):  
Candidate Genes ◽  
Intestinal Pseudo Obstruction

Antroduodenal Manometry Is Abnormal in Children Presenting With Orthostatic Intolerance and Gastrointestinal Symptoms

2016 ◽  
Vol 63 (3) ◽  
pp. 329-335 ◽  
Author(s):  
Jeffrey P. Moak ◽  
Robin R. Fabian ◽  
Lindsay C. Clarke ◽  
Sridhar Hanumanthaiah ◽  
John Desbiens ◽  
...  
Keyword(s):  
Orthostatic Intolerance ◽  
Gastrointestinal Symptoms ◽  
Antroduodenal Manometry

scholarly journals Mutations in RAD21 Disrupt Regulation of APOB in Patients With Chronic Intestinal Pseudo-Obstruction

2015 ◽  
Vol 148 (4) ◽  
pp. 771-782.e11 ◽  
Author(s):  
Elena Bonora ◽  
Francesca Bianco ◽  
Lina Cordeddu ◽  
Michael Bamshad ◽  
Ludmila Francescatto ◽  
...  
Keyword(s):  
Intestinal Pseudo Obstruction
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