scholarly journals Clinical associations of functional dyspepsia with gastric dysrhythmia on electrogastrography: A comprehensive systematic review and meta‐analysis

2021 ◽  
Author(s):  
Chris Varghese ◽  
Daniel A. Carson ◽  
Sameer Bhat ◽  
Tommy C. L. Hayes ◽  
Armen A. Gharibans ◽  
...  
Keyword(s):  
Systematic Review ◽  
Functional Dyspepsia ◽  
Meta Analysis ◽  
Gastric Dysrhythmia ◽  
Clinical Associations

scholarly journals Clinical Associations of Functional Dyspepsia with Gastric Dysrhythmia on Electrogastrography: A Comprehensive Systematic Review and Meta-Analysis

2021 ◽  
Author(s):  
C Varghese ◽  
DA Carson ◽  
S Bhat ◽  
TCL Hayes ◽  
AA Gharibans ◽  
...  
Keyword(s):  
Functional Dyspepsia ◽  
Slow Wave ◽  
Meta Analysis ◽  
Dominant Frequency ◽  
Gastric Electrical Activity ◽  
Gastric Dysrhythmia ◽  
Gastric Slow Wave ◽  
Clinical Associations ◽  
Secondary Outcomes ◽  
Underlying Mechanisms

AbstractBackgroundFunctional dyspepsia (FD) is a common gastroduodenal disorder, yet its pathophysiology remains poorly understood. Bioelectrical gastric slow wave abnormalities are thought to contribute to its multifactorial pathophysiology. Electrogastrography (EGG) has been used to record gastric electrical activity, however the clinical associations require further evaluation.AimsThis study aimed to systematically assess the clinical associations of EGG in FD.MethodsMEDLINE, EMBASE, and CENTRAL databases were systematically searched for articles using EGG in adults with FD. Primary outcomes were percentage normal vs abnormal rhythm (bradygastria, normogastria, tachygastria). Secondary outcomes were dominant power, dominant frequency, percentage coupling and the meal responses.Results1751 FD patients and 555 controls from 47 studies were included. FD patients spent less time in normogastria while fasted (SMD −0.74; 95%CI −1.22 - −0.25) and postprandially (−0.86; 95%CI −1.35 - −0.37) compared to controls. FD patients also spent more fasted time in bradygastria (0.63; 95%CI 0.33 – 0.93) and tachygastria (0.45; 95%CI 0.12 – 0.78%). The power ratio (−0.17; 95%CI −0.83 - 0.48), and dominant frequency meal-response ratio (0.06; 95%CI −0.08 - 0.21) were not significantly different to controls. Correlations between EGG metrics and the presence and timing of FD symptoms were inconsistent. EGG methodologies were diverse and variably applied.ConclusionAbnormal gastric slow wave rhythms are a consistent abnormality present in FD, as defined by EGG, and therefore likely play a role in pathophysiology. The aberrant electrophysiology identified in FD warrants further investigation, including into underlying mechanisms, associated spatial patterns, and symptom correlations.

scholarly journals Tu1310 – Efficacy and Safety of Soyo-San For the Treatment of Functional Dyspepsia: Systematic Review and Meta-Analysis

2019 ◽  
Vol 156 (6) ◽  
pp. S-1023
Author(s):  
Seok Jae Ko ◽  
Soo-Ho Cho ◽  
Keumji Kim ◽  
Braden Kuo ◽  
Jinsung Kim ◽  
...  
Keyword(s):  
Systematic Review ◽  
Functional Dyspepsia ◽  
Meta Analysis ◽  
Efficacy And Safety

Efficacy of Rebamipide in Organic and Functional Dyspepsia: A Systematic Review and Meta-Analysis

2017 ◽  
Vol 63 (5) ◽  
pp. 1250-1260 ◽  
Author(s):  
Mohamed Hasif Jaafar ◽  
Sher Zaman Safi ◽  
Maw-Pin Tan ◽  
Sanjay Rampal ◽  
Sanjiv Mahadeva
Keyword(s):  
Systematic Review ◽  
Functional Dyspepsia ◽  
Meta Analysis

Acute Gastroenteritis and the Risk of Functional Dyspepsia: A Systematic Review and Meta-Analysis

2013 ◽  
Vol 108 (10) ◽  
pp. 1558-1563 ◽  
Author(s):  
Brian L Pike ◽  
Chad K Porter ◽  
Tia J Sorrell ◽  
Mark S Riddle
Keyword(s):  
Systematic Review ◽  
Functional Dyspepsia ◽  
Acute Gastroenteritis ◽  
Meta Analysis

scholarly journals Antidepressants in the Treatment of Functional Dyspepsia: A Systematic Review and Meta-Analysis

PLoS ONE ◽  
2016 ◽  
Vol 11 (6) ◽  
pp. e0157798 ◽  
Author(s):  
Yaoyao Lu ◽  
Meng Chen ◽  
Zhiyin Huang ◽  
Chengwei Tang
Keyword(s):  
Systematic Review ◽  
Functional Dyspepsia ◽  
Meta Analysis

scholarly journals Acotiamide and Functional Dyspepsia: A Systematic Review and Meta-Analysis

Cureus ◽  
2021 ◽  
Author(s):  
Dhan B Shrestha ◽  
Pravash Budhathoki ◽  
Prarthana Subedi ◽  
Manita Khadka ◽  
Prabesh Karki ◽  
...  
Keyword(s):  
Systematic Review ◽  
Functional Dyspepsia ◽  
Meta Analysis
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