Normal acid exposure time in esophageal pH monitoring in Asian and Western populations: A systematic review and meta‐analysis

Author(s):  
Seung Young Kim ◽  
Hye‐Kyung Jung ◽  
Hye Ah Lee
2012 ◽  
Vol 142 (5) ◽  
pp. S-425
Author(s):  
Michel R. Fernandes ◽  
Juliane S. Lima ◽  
Marina Oliveira ◽  
Raquel Wolfart ◽  
Fernando Fornari

2021 ◽  
Vol 12 ◽  
pp. 204062232110567
Author(s):  
Yiqing Zhu ◽  
Junjun Tang ◽  
Wenbo Shi ◽  
Shengyuan Wang ◽  
Mingyan Wu ◽  
...  

Background: The objective of this study was to compare the predictive accuracy of the acid exposure time (AET) with the DeMeester score (DMS) for gastroesophageal reflux–induced cough (GERC). Methods: A total of 277 patients who underwent multichannel intraluminal impedance pH monitoring (MII-pH) were enrolled, and their clinical information and laboratory results were retrospectively analyzed. The diagnostic value of AET for GERC was compared with that of the DMS, symptom association probability (SAP), and symptom index (SI). Results: A total of 236 patients met the inclusion criteria, 150 patients (63.65%) were definitely diagnosed with GERC, including 111(74%) acid GERC and 39 (26%) nonacid GERC. The optimal cutoff value of AET for diagnosing GERC was AET > 4.8%, and its diagnostic value was equal to that of DMS > 14.7 (AUC = 0.827 versus 0.818, p = 0.519) and was superior to that of SAP (AUC = 0.827 versus 0.689, p = 0.000) and SI (AUC = 0.827 versus 0.688, p = 0.000). When using both DMS > 14.7 and AET > 4.8% or either of the two for the diagnosis of GERC, the diagnosis rate was not improved over using DMS > 14.7 alone. The diagnostic value of AET and DMS for acid GERC were both high and equivalent (AUC = 0.925 versus 0.922, p = 0.95). The optimal cutoff value of AET for diagnosing acid GERC was AET > 6.2%. Conclusion: AET and DMS are both equal in discriminating GERC. A GERC diagnosis should be considered when AET > 4.8%, whereas an acid GERC diagnosis should be considered when AET > 6.2%.


Author(s):  
Andrea Balla ◽  
Francesca Meoli ◽  
Livia Palmieri ◽  
Diletta Corallino ◽  
Maria Carlotta Sacchi ◽  
...  

Abstract Purpose Aim of this systematic review is to assess the changes in esophageal motility and acid exposure of the esophagus through esophageal manometry and 24-hours pH-monitoring before and after laparoscopic sleeve gastrectomy (LSG). Methods Articles in which all patients included underwent manometry and/or 24-hours pH-metry or both, before and after LSG, were included. The search was carried out in the PubMed, Embase, Cochrane, and Web of Science databases, revealing overall 13,769 articles. Of these, 9702 were eliminated because they have been found more than once between the searches. Of the remaining 4067 articles, further 4030 were excluded after screening the title and abstract because they did not meet the inclusion criteria. Thirty-seven articles were fully analyzed, and of these, 21 further articles were excluded, finally including 16 articles. Results Fourteen and twelve studies reported manometric and pH-metric data from 402 and 547 patients, respectively. At manometry, a decrease of the lower esophageal sphincter resting pressure after surgery was observed in six articles. At 24-hours pH-metry, a worsening of the DeMeester score and/or of the acid exposure time was observed in nine articles and the de novo gastroesophageal reflux disease (GERD) rate that ranged between 17.8 and 69%. A meta-analysis was not performed due to the heterogeneity of data. Conclusions After LSG a worsening of GERD evaluated by instrumental exams was observed such as high prevalence of de novo GERD. However, to understand the clinical impact of LSG and the burden of GERD over time further long-term studies are necessary.


1986 ◽  
Vol 8 ◽  
pp. 59-67 ◽  
Author(s):  
Hurt W. Ward ◽  
Wallace C. Wu ◽  
Joel E. Richter ◽  
Kin W. Lui ◽  
Donald O. Castell

1988 ◽  
Vol 155 (3) ◽  
pp. 503-508 ◽  
Author(s):  
William G. Cheadle ◽  
Gary C. Vitale ◽  
Sami A. Sadek ◽  
Alfred Cuschleri

2017 ◽  
Vol 152 (5) ◽  
pp. S652-S653
Author(s):  
Leonardo Frazzoni ◽  
Marzio Frazzoni ◽  
Nicola de Bortoli ◽  
Salvatore Tolone ◽  
Manuele Furnari ◽  
...  

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