scholarly journals Multiple rapid swallows and rapid drink challenge in patients with esophagogastric junction outflow obstruction on high‐resolution manometry

2020 ◽  
Author(s):  
Amanda J. Krause ◽  
Hui Su ◽  
Joseph R. Triggs ◽  
Claire Beveridge ◽  
Alexandra J. Baumann ◽  
...  
Keyword(s):  
High Resolution ◽  
Esophagogastric Junction ◽  
Outflow Obstruction ◽  
High Resolution Manometry

scholarly journals Physiological and pathological roles of the accommodation response in lower esophageal sphincter relaxation during wet swallows

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kazumasa Muta ◽  
Eikichi Ihara ◽  
Shohei Hamada ◽  
Hiroko Ikeda ◽  
Masafumi Wada ◽  
...  
Keyword(s):  
Clinical Practice ◽  
High Resolution ◽  
Observational Study ◽  
Lower Esophageal Sphincter ◽  
Relaxation Function ◽  
Esophagogastric Junction ◽  
Prospective Observational Study ◽  
Outflow Obstruction ◽  
High Resolution Manometry ◽  
Esophageal Sphincter

AbstractThe preparatory accommodation response of lower esophageal sphincter (LES) before swallowing is one of the mechanisms involved in LES relaxation during wet swallows, however, the physiological and/or pathological roles of LES accommodation remain to be determined in humans. To address this problem, we conducted a prospective observational study of 38 patients with normal high-resolution manometry (HRM) and 23 patients with idiopathic esophagogastric junction outflow obstruction (EGJOO) to assess dry and wet swallows. The LES accommodation measurement was proposed for practical use in evaluating the LES accommodation response. Although swallow-induced LES relaxation was observed in both dry and wet swallows, LES accommodation (6.4, 3.1–11.1 mmHg) was only observed in wet swallows. The extent of LES accommodation was impaired in idiopathic EGJOO (0.6, − 0.6–6 mmHg), and the LES accommodation measurement of patients with idiopathic EGJOO (36.8, 29.5–44.3 mmHg) was significantly higher in comparison to those with normal HRM (23.8, 18–28.6 mmHg). Successful LES relaxation in wet swallowing can be achieved by LES accommodation in combination with swallow-induced LES relaxation. Impaired LES accommodation is characteristic of idiopathic EGJOO. In addition to the IRP value, the LES accommodation measurement may be useful for evaluating the LES relaxation function in clinical practice.

Characterization and follow-up of esophagogastric junction outflow obstruction detected by high resolution manometry

2015 ◽  
Vol 28 (1) ◽  
pp. 116-126 ◽  
Author(s):  
M.-T. Pérez-Fernández ◽  
C. Santander ◽  
A. Marinero ◽  
D. Burgos-Santamaría ◽  
C. Chavarría-Herbozo
Keyword(s):  
High Resolution ◽  
Esophagogastric Junction ◽  
Outflow Obstruction ◽  
High Resolution Manometry

Mo1719 The Clinical Spectrum of Esophagogastric Junction Outflow Obstruction Identified via High Resolution Manometry

2013 ◽  
Vol 144 (5) ◽  
pp. S-1099 ◽  
Author(s):  
Poochong Timratana ◽  
Michal J. Lada ◽  
Dylan R. Nieman ◽  
Michelle S. Han ◽  
Christian G. Peyre ◽  
...  
Keyword(s):  
High Resolution ◽  
Esophagogastric Junction ◽  
Clinical Spectrum ◽  
Outflow Obstruction ◽  
High Resolution Manometry

140 MULTIPLE RAPID SWALLOWS AND RAPID DRINK CHALLENGE IN PATIENTS WITH ESOPHAGOGASTRIC JUNCTION OUTFLOW OBSTRUCTION ON HIGH-RESOLUTION MANOMETRY

2020 ◽  
Vol 158 (6) ◽  
pp. S-29
Author(s):  
Amanda J. Krause ◽  
Hui Su ◽  
Dustin Carlson ◽  
Joseph Triggs ◽  
Claire Beveridge ◽  
...  
Keyword(s):  
High Resolution ◽  
Esophagogastric Junction ◽  
Outflow Obstruction ◽  
High Resolution Manometry
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