scholarly journals The clinical and economical impact of postoperative ileus in patients undergoing colorectal surgery

2020 ◽  
Vol 32 (8) ◽  
Author(s):  
Emmeline G. Peters ◽  
Madhuri Pattamatta ◽  
Boudewijn J. J. Smeets ◽  
Daan J. Brinkman ◽  
Silvia M. A. A. Evers ◽  
...  
Keyword(s):  
Colorectal Surgery ◽  
Postoperative Ileus

PyRICo‐Pilot – Pyridostigmine to reduce the duration of postoperative ileus after colorectal surgery – a phase II study

2021 ◽  
Author(s):  
Nagendra N Dudi‐Venkata ◽  
Hidde M Kroon ◽  
Sergei Bedrikovetski ◽  
Luke Traeger ◽  
Mark Lewis ◽  
...  
Keyword(s):  
Colorectal Surgery ◽  
Phase Ii ◽  
Postoperative Ileus ◽  
Phase Ii Study

Goal-directed Fluid Therapy Does Not Reduce Primary Postoperative Ileus after Elective Laparoscopic Colorectal Surgery

2017 ◽  
Vol 127 (1) ◽  
pp. 36-49 ◽  
Author(s):  
Juan C. Gómez-Izquierdo ◽  
Alessandro Trainito ◽  
David Mirzakandov ◽  
Barry L. Stein ◽  
Sender Liberman ◽  
...  
Keyword(s):  
Colorectal Surgery ◽  
Fluid Therapy ◽  
Postoperative Ileus ◽  
Enhanced Recovery ◽  
Laparoscopic Colorectal Surgery ◽  
Enhanced Recovery After Surgery ◽  
Therapy Group ◽  
Control Group ◽  
Goal Directed Fluid Therapy ◽  
The Impact

Abstract Background Inadequate perioperative fluid therapy impairs gastrointestinal function. Studies primarily evaluating the impact of goal-directed fluid therapy on primary postoperative ileus are missing. The objective of this study was to determine whether goal-directed fluid therapy reduces the incidence of primary postoperative ileus after laparoscopic colorectal surgery within an Enhanced Recovery After Surgery program. Methods Randomized patient and assessor-blind controlled trial conducted in adult patients undergoing laparoscopic colorectal surgery within an Enhanced Recovery After Surgery program. Patients were assigned randomly to receive intraoperative goal-directed fluid therapy (goal-directed fluid therapy group) or fluid therapy based on traditional principles (control group). Primary postoperative ileus was the primary outcome. Results One hundred twenty-eight patients were included and analyzed (goal-directed fluid therapy group: n = 64; control group: n = 64). The incidence of primary postoperative ileus was 22% in the goal-directed fluid therapy and 22% in the control group (relative risk, 1; 95% CI, 0.5 to 1.9; P = 1.00). Intraoperatively, patients in the goal-directed fluid therapy group received less intravenous fluids (mainly less crystalloids) but a greater volume of colloids. The increase of stroke volume and cardiac output was more pronounced and sustained in the goal-directed fluid therapy group. Length of hospital stay, 30-day postoperative morbidity, and mortality were not different. Conclusions Intraoperative goal-directed fluid therapy compared with fluid therapy based on traditional principles does not reduce primary postoperative ileus in patients undergoing laparoscopic colorectal surgery in the context of an Enhanced Recovery After Surgery program. Its previously demonstrated benefits might have been offset by advancements in perioperative care.

Machine learning models for prediction of postoperative ileus in patients underwent laparoscopic colorectal surgery

2020 ◽  
Author(s):  
Xueyan Li ◽  
Genshan Ma ◽  
Xiaobo Qian ◽  
Yamou Wu ◽  
Xiaochen Huang ◽  
...  
Keyword(s):  
Machine Learning ◽  
Risk Factors ◽  
Colorectal Surgery ◽  
Decision Tree ◽  
Risk Prediction ◽  
Postoperative Ileus ◽  
Laparoscopic Colorectal Surgery ◽  
Machine Learning Algorithms ◽  
Gradient Boosting ◽  
Malignant Lesions

Abstract Background: We aimed to assess the performance of machine learning algorithms for the prediction of risk factors of postoperative ileus (POI) in patients underwent laparoscopic colorectal surgery for malignant lesions. Methods: We conducted analyses in a retrospective observational study with a total of 637 patients at Suzhou Hospital of Nanjing Medical University. Four machine learning algorithms (logistic regression, decision tree, random forest, gradient boosting decision tree) were considered to predict risk factors of POI. The total cases were randomly divided into training and testing data sets, with a ratio of 8:2. The performance of each model was evaluated by area under receiver operator characteristic curve (AUC), precision, recall and F1-score. Results: The morbidity of POI in this study was 19.15% (122/637). Gradient boosting decision tree reached the highest AUC (0.76) and was the best model for POI risk prediction. In addition, the results of the importance matrix of gradient boosting decision tree showed that the five most important variables were time to first passage of flatus, opioids during POD3, duration of surgery, height and weight. Conclusions: The gradient boosting decision tree was the optimal model to predict the risk of POI in patients underwent laparoscopic colorectal surgery for malignant lesions. And the results of our study could be useful for clinical guidelines in POI risk prediction.

scholarly journals Postoperative ileus in colorectal surgery: is there any difference between laparoscopic and open surgery?

2013 ◽  
Vol 1 (2) ◽  
pp. 138-143 ◽  
Author(s):  
M. Fesharakizadeh ◽  
D. Taheri ◽  
S. Dolatkhah ◽  
S. D. Wexner
Keyword(s):  
Colorectal Surgery ◽  
Open Surgery ◽  
Postoperative Ileus

scholarly journals Nicotine chewing gum for the prevention of postoperative ileus after colorectal surgery: a multicenter, double-blind, randomised, controlled pilot study

2017 ◽  
Vol 32 (9) ◽  
pp. 1267-1275 ◽  
Author(s):  
Daniël P. V. Lambrichts ◽  
Geesien S. A. Boersema ◽  
Buket Tas ◽  
Zhouqiao Wu ◽  
Wietske W. Vrijland ◽  
...  
Keyword(s):  
Pilot Study ◽  
Colorectal Surgery ◽  
Postoperative Ileus ◽  
Chewing Gum ◽  
Double Blind ◽  
Randomised Controlled

scholarly journals The effect of coffee/caffeine on postoperative ileus following elective colorectal surgery: a meta-analysis of randomized controlled trials

2022 ◽  
Author(s):  
Tzu-Wei Yang ◽  
Chi-Chih Wang ◽  
Wen-Wei Sung ◽  
Wen-Chien Ting ◽  
Chun-Che Lin ◽  
...  
Keyword(s):  
Colorectal Surgery ◽  
Hospital Stay ◽  
Randomized Controlled Trials ◽  
Postoperative Ileus ◽  
Bowel Movement ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Caffeine Consumption ◽  
Elective Colorectal Surgery ◽  
Randomized Controlled

Abstract Purpose Postoperative ileus (POI) is the most common complication of elective colon resection. Coffee or caffeine has been reported to be useful in improving gastrointestinal function after abdominal surgery. This study aimed to investigate the effect of coffee/caffeine on POI in patients undergoing elective colorectal surgery. Methods We searched Cochrane library, Embase, PubMed, and ClinicalTrials.gov (until July 2021) to identify randomized controlled trials (RCTs) evaluating the effect of coffee or caffeine on bowel movements and POI in patients undergoing elective colorectal surgery. The mean difference (MD) for continuous outcomes and risk ratio (RR) for dichotomous outcomes were calculated and are presented with 95% confidence intervals (CIs). A random effects model was used in all meta-analyses. Results A total of four RCTs including 312 subjects met the inclusion criteria and were included in the meta-analysis. Postoperative coffee or caffeine consumption decreased the time to first bowel movement (MD, − 10.36 h; 95% CI, − 14.61 to − 6.11), shortened the length of hospital stay (MD, − 0.95 days; 95% CI, − 1.57 to − 0.34), and was associated with a decreased risk of the use of any laxatives after the procedure (RR, 0.64; 95% CI, 0.44 to 0.92). The time to first flatus, time to tolerance of solid food, risk of any postoperative complication, postoperative reinsertion of a nasogastric (NG) tube, and anastomotic leakage showed no statistical differences between groups. Conclusion Postoperative coffee or caffeine consumption improved bowel movement and decreased the duration of hospital stay in patients undergoing elective colorectal surgery. This method is safe and can prevent or treat POI.

Sign in / Sign up

Export Citation Format

Share Document