scholarly journals Characterization of esophageal motility and esophagogastric junction in preterm infants with bronchopulmonary dysplasia

2020 ◽  
Vol 32 (7) ◽  
Author(s):  
Maissa Rayyan ◽  
Taher Omari ◽  
Anne Debeer ◽  
Karel Allegaert ◽  
Nathalie Rommel
Keyword(s):  
Preterm Infants ◽  
Bronchopulmonary Dysplasia ◽  
Esophageal Motility ◽  
Esophagogastric Junction

Characterization of lung ultrasound imaging in preterm infants with bronchopulmonary dysplasia

2021 ◽  
pp. 1-13
Author(s):  
Ying-Hua Sun ◽  
Lin Yuan ◽  
Yang Du ◽  
Jian-Guo Zhou ◽  
Sam Bill Lin ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Bronchopulmonary Dysplasia ◽  
Neonatal Intensive Care ◽  
Lung Ultrasound ◽  
Imaging Method ◽  
Chronic Lung Diseases ◽  
Pleural Line ◽  
Ultrasound Features

BACKGROUND: Lung ultrasound (LUS) is a bedside technique that can be used on diagnosis and follow-up of neonatal respiratory diseases. However, there are rare reports on the ultrasound features of bronchopulmonary dysplasia (BPD) which is one of the most common chronic lung diseases in preterm infants. OBJECTIVE: To describe the ultrasound features of different BPD levels, and to investigate the value of ultrasound in evaluating moderate-to-severe BPD. METHODS: In this prospective cohort study, newborns of less than 37 weeks’ gestational age in neonatal intensive care unit (NICU) were included. The LUS characteristics including pleural line, alveolar-interstitial syndrome (AIS), retrodiaphragmatic hyperechogenicity and diaphragmatic morphology were observed and recorded. The reliability of LUS in evaluating moderate and severe BPD were compared and calculated. RESULTS: A total of 108 infants were enrolled in our study: 39, 24, 29, 16 infants had non, mild, moderate and severe BPD. The median(IQR) pleura thickness in the moderate-to-severe BPD group was 1.7(1.6–1.85) mm, which was thicker than that in the none-to-mild BPD infants (P <  0.001), meanwhile the proportions of rough pleural lines, diffuse AIS, retrodiaphragmatic hyperechogenicity, small cysts above the diaphragm and rough diaphragm in the moderate-to-severe BPD group were also higher than those in none-to-mild BPD group (86.7% vs 36.5, 57.8% vs 7.9%, 37.8% vs 0, 33.3% vs 0, P <  0.001). In evaluating moderate-to-severe BPD, rough pleura had 91.1% (95% confidence interval [CI]: 0.793–0.965) in sensitivity, 91.3% (95% CI: 0.797–0.966) in negative predictive value (NPV), and 66.7% (95% CI: 0.544–0.771) in specificity. Small cysts had 100% (95% CI: 0.941-1) in specificity, 100% (95% CI: 0.816-1) in PPV, and 37.8% in sensitivity (95% CI: 0.251–0.524). Rough diaphragm had 100% (95% CI: 0.943-1) in sensitivity, 100% (95% CI: 0.796-1) in PPV and 33.3% (95% CI: 0.211–0.478) in specificity. CONCLUSIONS: Depending on its unique advantages such as convenient, no radiation and repeatable, LUS is a valuable imaging method in assessing the severity of BPD, especially in moderate and severe BPD.

scholarly journals Characterization of Ureaplasmas Isolated from Preterm Infants with and without Bronchopulmonary Dysplasia

2005 ◽  
Vol 43 (9) ◽  
pp. 4852-4854 ◽  
Author(s):  
B. Katz ◽  
P. Patel ◽  
L. Duffy ◽  
R. L. Schelonka ◽  
R. A. Dimmitt ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Bronchopulmonary Dysplasia

scholarly journals Characterization of Disease Phenotype in Very Preterm Infants with Severe Bronchopulmonary Dysplasia

2020 ◽  
Vol 201 (11) ◽  
pp. 1398-1406 ◽  
Author(s):  
Katherine Y. Wu ◽  
Erik A. Jensen ◽  
Ammie M. White ◽  
Yan Wang ◽  
David M. Biko ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Bronchopulmonary Dysplasia ◽  
Disease Phenotype ◽  
Very Preterm Infants ◽  
Very Preterm

scholarly journals Maturation of Esophageal Motility and Esophagogastric Junction in Preterm Infants

Neonatology ◽  
2020 ◽  
Vol 117 (4) ◽  
pp. 495-503 ◽  
Author(s):  
Maissa Rayyan ◽  
Taher Omari ◽  
Gunnar Naulaers ◽  
Raf Aerts ◽  
Karel Allegaert ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Repeated Measures ◽  
Esophageal Motility ◽  
Esophagogastric Junction ◽  
Oral Feeding ◽  
Preterm Neonates ◽  
Feeding Problems ◽  
High Resolution Manometry ◽  
Time Points ◽  
The Mean

<b><i>Background:</i></b> Preterm infants commonly present with oral feeding problems. The role of maturation of esophageal bolus transport mechanisms herein remains unclear. <b><i>Objectives:</i></b> To characterize esophageal motility and function of esophagogastric junction (EGJ) during deglutitive swallowing in healthy preterm infants and to describe maturational changes. <b><i>Methods:</i></b> Four consecutive high-resolution manometry studies with impedance studies were performed weekly to investigate esophageal motility and EGJ function. Esophageal pressure topography and pressure-impedance metrics were derived. Mixed models with repeated measures were used for statistical analysis. <b><i>Results:</i></b> We analyzed 137 nutritive swallows from 36 motility studies in 10 preterm infants. The mean gestational age was 30.17 ± 0.94 weeks; the mean postmenstrual age at time point 1 and 4 was 34.42 ± 0.86 and 37.45 ± 1.16 weeks, respectively. Esophageal peristaltic wave patterns in response to nutritive swallows were observed in all patients. At later time points, esophageal body peristalsis became more rapid, evidenced by a faster distal contractile velocity and shorter distal latency (<i>p</i> = 0.002 and <i>p</i> &#x3c; 0.0001, respectively). In addition, 4-s integrated relaxation pressures increased and distal contractile integral decreased at later time points (<i>p</i> = 0.003 and <i>p</i> = 0.021, respectively). Bolus clearance also improved at later age (<i>p</i> = 0.008). <b><i>Conclusions:</i></b> Preterm infants demonstrate peristaltic esophageal motility following nutritive swallows. However, alterations in esophageal bolus transport in relation to peristalsis are demonstrated. Peristaltic progression becomes more rapid, while deglutitive relaxation pressures increase with increasing age. These maturational changes may suggest further development of the enteric nervous system after birth in former preterm neonates.

Fluid status in the first 10 days of life and death/bronchopulmonary dysplasia among preterm infants

2021 ◽  
Author(s):  
Safiya Soullane ◽  
Sharina Patel ◽  
Martine Claveau ◽  
Laila Wazneh ◽  
Guilherme Sant’Anna ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Bronchopulmonary Dysplasia ◽  
Life And Death ◽  
Fluid Status

scholarly journals Stem cells for bronchopulmonary dysplasia in preterm infants: A randomized controlled phase II trial

2021 ◽  
Author(s):  
So Yoon Ahn ◽  
Yun Sil Chang ◽  
Myung Hee Lee ◽  
Se In Sung ◽  
Byong Sop Lee ◽  
...  
Keyword(s):  
Stem Cells ◽  
Preterm Infants ◽  
Bronchopulmonary Dysplasia ◽  
Phase Ii ◽  
Phase Ii Trial ◽  
Randomized Controlled

Higher Altitude and Risk of Bronchopulmonary Dysplasia among Preterm Infants

2012 ◽  
Vol 30 (07) ◽  
pp. 601-606 ◽  
Author(s):  
Shoo Lee ◽  
Xiang Ye ◽  
Nalini Singhal ◽  
Sarah De La Rue ◽  
Abhay Lodha ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Bronchopulmonary Dysplasia
Sign in / Sign up

Export Citation Format

Share Document