scholarly journals Lactose intolerance but not lactose maldigestion is more frequent in patients with irritable bowel syndrome than in healthy controls: A meta‐analysis

2018 ◽  
Vol 31 (5) ◽  
pp. e13527 ◽  
Author(s):  
Péter Varjú ◽  
Noémi Gede ◽  
Zsolt Szakács ◽  
Péter Hegyi ◽  
Irina Mihaela Cazacu ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Lactose Intolerance ◽  
Meta Analysis ◽  
Healthy Controls ◽  
Lactose Maldigestion ◽  
Irritable Bowel

scholarly journals The level and prevalence of depression and anxiety among patients with different subtypes of irritable bowel syndrome: a network meta-analysis

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Zhichao Hu ◽  
Meixuan Li ◽  
Liang Yao ◽  
Yinshu Wang ◽  
Enkang Wang ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Anxiety And Depression ◽  
Healthy Controls ◽  
Depression And Anxiety ◽  
Significant Difference ◽  
Prevalence Of Depression ◽  
The Difference ◽  
Irritable Bowel

Abstract Background Irritable bowel syndrome (IBS) is a very common functional bowel disorder. However, the difference of depression and anxiety comorbidities among different IBS subtypes is still not well evaluated. This study aims to investigate the difference in the level and prevalence of depression and anxiety among healthy controls and patients with different subtypes of IBS. Methods PubMed, EMBASE and the Cochrane library were searched systematically until August 17, 2020. Studies that investigated depression and/or anxiety levels or prevalence among different IBS-subtype patients measured at baseline or the same point were included. Network meta-analysis was conducted to analyze standardized mean difference (SMD) of anxiety and depression levels, and single arm meta-analysis was performed for prevalence of anxiety and depression among different IBS subtypes. Results Eighteen studies involving 7095 participants were included. Network meta-analyses results showed healthy controls had a lower level of depression than IBS with mixed symptoms of constipation and diarrhea (IBS-M) [SMD =  − 1.57; 95% confidence interval (CI) − 2.21,  − 0.92], IBS with constipation (IBS-C) (SMD =  − 1.53; 95% CI − 2.13,  − 0.93) and IBS with diarrhea (IBS-D)(SMD =  − 1.41; 95% CI − 1.97,  − 0.85), while no significant difference was found between IBS unclassified (IBS-U) and healthy controls (SMD =  − 0.58; 95% CI  − 2.15, 1.00). There was also no significant difference in the level of depression among different IBS subtypes patients. The results of anxiety were similar to depression. Ranking probability showed that IBS-M was associated with the highest level of depression and anxiety symptoms, followed by IBS-C/IBS-D and IBS-U. Single-arm meta-analysis showed IBS-C had the highest prevalence of depression (38%) and anxiety (40%), followed by IBS-D, IBS-M and IBS-U. Conclusion The results indicated that IBS-M was more likely to be associated with a higher level of depression and anxiety, and the prevalence of depression and anxiety in IBS-C was highest. The psychological screening and appropriate psychotherapy are needed for patients with IBS-C, IBS-D and IBS-M instead of IBS-U.

Lactose maldigestion does not explain subjective intolerance for diary products in the irritable bowel syndrome (IBS)

2001 ◽  
Vol 120 (5) ◽  
pp. A756-A756
Author(s):  
M SIMREN ◽  
A MANSSON ◽  
U BENGTSSON ◽  
H ABRAHAMSSON ◽  
A KILANDER ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Lactose Maldigestion ◽  
Irritable Bowel
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