scholarly journals The effect of arabinoxylooligosaccharides on upper gastroduodenal motility and hunger ratings in humans

2018 ◽  
Vol 30 (7) ◽  
pp. e13306
Author(s):  
E. Scarpellini ◽  
E. Deloose ◽  
R. Vos ◽  
I. Francois ◽  
J. A. Delcour ◽  
...  
1984 ◽  
Vol 20 (6) ◽  
pp. 493-499
Author(s):  
Toshio NISHIOKA ◽  
Toshikazu SEKIGUCHI ◽  
Michio KOGURE ◽  
Motoyasu KUSANO ◽  
Tsutomu HORIKOSHI ◽  
...  

2008 ◽  
Vol 1 (2) ◽  
pp. 99-104 ◽  
Author(s):  
M. Bortolotti ◽  
S. Mattioli ◽  
G. Alampi ◽  
G. Giangaspero ◽  
L. Barbara

PEDIATRICS ◽  
1987 ◽  
Vol 80 (3) ◽  
pp. 434-438
Author(s):  
T. Tomomasa ◽  
P. E. Hyman ◽  
K. Itoh ◽  
J. Y. Hsu ◽  
T. Koizumi ◽  
...  

It is known that breast milk empties more quickly from the stomach than does infant formula. We studied the difference in gastroduodenal motility between neonates fed with human milk and those fed with infant formula. Twenty-four five-to 36-day-old neonates were fed with mother's breast milk or with a cow's milk-based formula. Postprandlial gastroduodenal contractions were recorded manometrically for three hours. Repetitive, high-amplitude nonmigrating contractions were the dominant wave form during the postprandial period. The number of episodes, duration, amplitude, and frequency of nonmigrating contractions were not different following the different feedings. The migrating myoelectric complex, which signals a return to the interdigestive (fasting) state, appeared in 75% of breast milk-fed infants but only 17% of formula-fed infants (P < .05) within the three-hour recording period. Because contractions were similar following the two meals, but a fasting state recurred more rapidly in breast-fed infants, we conclude that factors other than phasic, nonpropagated antroduodenal contractions were responsible for the differences in gastric emptying between breast milk and formula.


1991 ◽  
Vol 100 (4) ◽  
pp. 892-900 ◽  
Author(s):  
David D. Kerrigan ◽  
Nicholas W. Read ◽  
Lesley A. Houghton ◽  
Marion E. Taylor ◽  
Alan G. Johnson

1993 ◽  
Vol 265 (5) ◽  
pp. G842-G850 ◽  
Author(s):  
V. Martinez ◽  
M. Jimenez ◽  
E. Gonalons ◽  
P. Vergara

Our objective was to study the mechanism of action of cholecystokinin (CCK) on the motility of the gastroduodenal area. Chickens were implanted with five electrodes for electromyography in the stomach and duodenum. The effects of CCK (10(-9) mol.kg-1.10 min-1) were studied against the presence of several antagonists and in vagotomized animals. CCK caused inhibition of gastric motility and duodenal hyperactivity. Vagotomy blocked CCK responses in the stomach but not in the duodenum. Hexamethonium partially blocked gastric inhibition induced by CCK. NG-nitro-L-arginine methyl ester blocked the inhibitory response to CCK in the stomach but did not modify duodenum response. L-Arginine did not modify CCK actions. Opioid antagonists naloxone and naltrindole and adrenergic antagonists phentolamine and propranolol did not modify CCK response. Atropine did not modify duodenal response to CCK. Sodium nitroprusside (10(-8)-10(-6) mol/kg) inhibited gastroduodenal activity in a dose-related manner. We suggest that gastric response to CCK is vagally mediated, mainly by the nitric oxide system. Duodenal hyperactivity seems to be a direct action of CCK. Nitric oxide is a putative neurotransmitter in the chicken gut.


1993 ◽  
Vol 264 (5) ◽  
pp. G928-G934 ◽  
Author(s):  
C. M. Prather ◽  
M. Camilleri ◽  
G. M. Thomforde ◽  
L. A. Forstrom ◽  
A. R. Zinsmeister

The aim of this study was to assess the relationship between altered axial forces and gastric emptying of solids by experimentally inhibiting or stimulating gastric axial forces by intraduodenal lipid or intravenous erythromycin, respectively. In 15 healthy volunteers, we simultaneously measured gastric emptying of solids by scintigraphy, gastroduodenal motility by manometry, and forces along the longitudinal axis of the distal stomach by an axial force transducer. When 25% of the radiolabel had emptied from the stomach, subjects (n = 5 in each group) received normal saline (controls), intraduodenal lipid, or intravenous erythromycin. The test period consisted of the infusion period (10 min) and the subsequent 30 min. Lipid significantly reduced and erythromycin increased axial forces compared with control (lipid: median 0.6 N [0-1.4 interquartile range (IQR)]; erythromycin: median 18.2 N (16.5-20.5 IQR); control: median 4.7 N (3.9-5.2 IQR); P < 0.01). Similarly, antral phasic pressure activities were different relative to control. Gastric axial forces correlated significantly with gastric emptying (Spearman rank correlation = 0.86; P < 0.01). These data are consistent with the hypothesis that axial forces affect gastric emptying of solids and suggest that measurement of axial forces provides an assessment of overall gastric propulsion during the emptying of solids.


1981 ◽  
Vol 81 (5) ◽  
pp. 910-914 ◽  
Author(s):  
Mauro Bortolotti ◽  
Nicola Pandolfo ◽  
Cristina Nebiacolombo ◽  
Giuseppe Labò ◽  
Francesco Mattioli

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