scholarly journals Novel 3D high-resolution manometry metrics for quantifying esophagogastric junction contractility

2017 ◽  
Vol 29 (8) ◽  
pp. e13054 ◽  
Author(s):  
Zhiyue Lin ◽  
Yinglian Xiao ◽  
Yuwen Li ◽  
John E. Pandolfino ◽  
Minhu Chen ◽  
...  
Keyword(s):  
High Resolution ◽  
Esophagogastric Junction ◽  
High Resolution Manometry

scholarly journals Physiological and pathological roles of the accommodation response in lower esophageal sphincter relaxation during wet swallows

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kazumasa Muta ◽  
Eikichi Ihara ◽  
Shohei Hamada ◽  
Hiroko Ikeda ◽  
Masafumi Wada ◽  
...  
Keyword(s):  
Clinical Practice ◽  
High Resolution ◽  
Observational Study ◽  
Lower Esophageal Sphincter ◽  
Relaxation Function ◽  
Esophagogastric Junction ◽  
Prospective Observational Study ◽  
Outflow Obstruction ◽  
High Resolution Manometry ◽  
Esophageal Sphincter

AbstractThe preparatory accommodation response of lower esophageal sphincter (LES) before swallowing is one of the mechanisms involved in LES relaxation during wet swallows, however, the physiological and/or pathological roles of LES accommodation remain to be determined in humans. To address this problem, we conducted a prospective observational study of 38 patients with normal high-resolution manometry (HRM) and 23 patients with idiopathic esophagogastric junction outflow obstruction (EGJOO) to assess dry and wet swallows. The LES accommodation measurement was proposed for practical use in evaluating the LES accommodation response. Although swallow-induced LES relaxation was observed in both dry and wet swallows, LES accommodation (6.4, 3.1–11.1 mmHg) was only observed in wet swallows. The extent of LES accommodation was impaired in idiopathic EGJOO (0.6, − 0.6–6 mmHg), and the LES accommodation measurement of patients with idiopathic EGJOO (36.8, 29.5–44.3 mmHg) was significantly higher in comparison to those with normal HRM (23.8, 18–28.6 mmHg). Successful LES relaxation in wet swallowing can be achieved by LES accommodation in combination with swallow-induced LES relaxation. Impaired LES accommodation is characteristic of idiopathic EGJOO. In addition to the IRP value, the LES accommodation measurement may be useful for evaluating the LES relaxation function in clinical practice.

scholarly journals 3D-high resolution manometry of the esophagogastric junction

2011 ◽  
Vol 23 (11) ◽  
pp. e461-e469 ◽  
Author(s):  
M. A. Kwiatek ◽  
J. E. Pandolfino ◽  
P. J. Kahrilas
Keyword(s):  
High Resolution ◽  
Esophagogastric Junction ◽  
High Resolution Manometry

The Value of High-Resolution Manometry in Measurement of EGJ Competency and Manometric Outcomes of Antireflux Surgery

2021 ◽  
Vol 1 (3) ◽  
pp. 227-233
Author(s):  
Sumeet K. Mittal ◽  
Komeil Mirzaei Baboli
Keyword(s):  
High Resolution ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Antireflux Surgery ◽  
Esophagogastric Junction ◽  
Normal Values ◽  
Pressure Profile ◽  
Objective Measures ◽  
High Resolution Manometry ◽  
Integral Role

The esophagogastric junction (EGJ) barrier plays an integral role in the prevention of gastroesophageal reflux; however, not much attention has been paid to competency parameters, especially in the era of high-resolution manometry (HRM). HRM provides a unique spatiotemporal pressure profile and measurements of the EGJ. Herein, we discuss the evidence for objective measures of EGJ competency, which should guide the clinical management of gastroesophageal reflux disease. Additionally, we will briefly discuss expected normal values after antireflux surgery.

Sa1345 Post-Swallow Esophagogastric Junction (EGJ) Contractility Assessment by High-Resolution Manometry (HRM) in Patients With Gastro-Esophageal Reflux Disease (GERD) and Healthy Controls

2016 ◽  
Vol 150 (4) ◽  
pp. S291
Author(s):  
Enrique Coss-Adame ◽  
Villar-Chavez Alicia Sofia ◽  
Jose M. Remes Troche ◽  
Enmanuel R. Espinal Gomez ◽  
Paulo Cesar Gomez-Castaños
Keyword(s):  
High Resolution ◽  
Reflux Disease ◽  
Esophagogastric Junction ◽  
Healthy Controls ◽  
Esophageal Reflux ◽  
High Resolution Manometry
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