Improvement of quality of life and symptoms after gastric electrical stimulation in children with functional dyspepsia

2013 ◽  
Vol 25 (7) ◽  
pp. 567-e456 ◽  
Author(s):  
P. L. Lu ◽  
S. Teich ◽  
C. D. Lorenzo ◽  
B. Skaggs ◽  
M. Alhajj ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Electrical Stimulation ◽  
Functional Dyspepsia ◽  
Gastric Electrical Stimulation

1085 Improvement of Quality of Life and Symptoms After Gastric Electrical Stimulation in Children With Gastroparesis and Functional Dyspepsia

2012 ◽  
Vol 142 (5) ◽  
pp. S-194-S-195
Author(s):  
Peter L. Lu ◽  
Steven Teich ◽  
Carlo Di Lorenzo ◽  
Jaya Punati ◽  
Beth Skaggs ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Electrical Stimulation ◽  
Functional Dyspepsia ◽  
Gastric Electrical Stimulation

scholarly journals Role of Gastric Electrical Stimulation in the Treatment of Gastroparesis

2020 ◽  
Vol 2 (1) ◽  
pp. 12-26 ◽  
Author(s):  
Amal Shine ◽  
Thomas L. Abell
Keyword(s):  
Quality Of Life ◽  
Electrical Stimulation ◽  
Symptom Control ◽  
Gastrointestinal Symptoms ◽  
Gastric Electrical Stimulation ◽  
Cochrane Library ◽  
Health Related ◽  
History Of ◽  
Future Work

Introduction: Gastric electrical stimulation (GES) is a surgically implanted treatment option for drug refractory gastroparesis syndromes. Evidence supporting use of GES and the pathophysiology of gastroparesis syndromes is not widely known. We conducted a descriptive review to elucidate the pathophysiology of gastroparesis syndromes, with particular focus on gastrointestinal neuromodulation and the known mechanisms of action of GES. Methods: A descriptive review of PubMed, Web of Science and Cochrane Library was conducted using the keywords gastric electrical stimulation, gastroparesis, nausea, vomiting, neuromodulation, gastroparesis syndromes, central nervous system, gastric pacing and electrical stimulation. Results: 1040 potentially relevant articles were identified, of which 34 were included. These studies explored various central and peripheral effects of GES, as well as its effect on quality of life, hospital stay, mortality and health-related costs. Conclusion: Although evidence supporting gastrointestinal (GI) electrical stimulation and GI neuromodulation use is not widely known, GES does seem to offer significant improvement in symptom control, quality of life and other effects to many patients. GES exerts its effects through multiple central and peripheral mechanisms and has potential to modify the natural history of disease. Future work on gastroparetic syndromes and their treatment might be better focused in terms of pathophysiologic mechanisms. Improving outcomes with specific neuromodulation therapies, like GES, may offer improvements in health for many patients with refractory upper gastrointestinal symptoms.

Mo1306 Gastric Electrical Stimulation Improves Symptoms and Quality of Life At Up to 12 Years Follow-Up in Refractory Gastroparesis

2014 ◽  
Vol 146 (5) ◽  
pp. S-614-S-615
Author(s):  
Alan Askari ◽  
Stefan S. Antonowicz ◽  
Jennifer Barras ◽  
Cheuk-Bong Tang ◽  
Michael Harvey ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Electrical Stimulation ◽  
Gastric Electrical Stimulation

scholarly journals O-BN08 Quality of Life 21 Years Following Gastric Pacing/ Gastric Electrical Stimulation for Gastroparesis – A real life data

2021 ◽  
Vol 108 (Supplement_9) ◽  
Author(s):  
Sritharan Kadirkamanathan ◽  
Ali Kordzadek ◽  
Etsuro Yazaki ◽  
Alan Askari ◽  
Priyantha Siriwardana ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Abdominal Pain ◽  
Electrical Stimulation ◽  
Hospital Admissions ◽  
Real Life ◽  
Gastric Electrical Stimulation ◽  
Wilcoxon Test ◽  
Safe Procedure ◽  
Parametric Data

Abstract Background Gastroparesis is defined as delayed emptying of the stomach in the absence of mechanical obstruction. Gastroparesis symptoms ranging from nausea, vomiting, bloating and abdominal pain with significant impact on overall quality of life (QALY). Gastric electrical stimulation (GES) for gastroparesis has been used in clinical practice since 1998 and was initially licensed as a “humanitarian” treatment when all else had failed. In the last two decades, it has been increasingly used in the treatment of refractory gastroparesis. We have been performing GES for refractory Gastroparesis since 2000 and we present our data on symptoms, quality of life and resource utilization Methods A prospective consecutive cohort study at a single center from December 2000 to July 2021 has been conducted. Data on patient demographics (gender and age), comorbidities, aetiology, the method of surgery, pre and post hospital stay, pre and post-operative SF-36 questionnaire (QALY) and symptom score (Likert Score), adjunct intervention, feeding regimen, mortality and morbidity were collated and subjected to student t-test for parametric data, the Wilcoxon test for non-parametric data, and McNemar’s test for binomial data Results A total of 162 patients underwent GES. There were 118 females. The median age was 36.5 years (range 6-80). Ninety-two patients were Idiopathic, 63 were Diabetic and 7 Post-Surgical. Overall QALY improved from a mean of 190/500 to 415/500(p = <0.001) with significant improvement in nausea (p = <0.001), abdominal pain (p = 0.005) and bloating (p = 0.001) severity score prior and following surgery. Number of hospital admissions (median) reduced post GES insertion from six to zero per year (p = 0.002). The median length of stay was 3 days (range 1-45) and follow up was up to 129 months (6-252). There was no mortality from the procedure. Conclusions This is one of a few long-term studies looking at the outcome following GES for Gastroparesis. Our data shows that GES is a safe procedure with very little morbidity and no mortality. It improves symptoms and quality of life. It also reduces the health care utilization for these patients. The effects of GES are also very durable and hence should be considered as a mainstream treatment for patients with refractory gastroparesis.

Healthcare consumption and quality of life in patients with functional dyspepsia after omeprazole treatment

1998 ◽  
Vol 114 ◽  
pp. A223
Author(s):  
V. Meineche-Schmidt ◽  
N.J. Talley ◽  
Á. Pap ◽  
H. Kordecki ◽  
V. Schmid ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Functional Dyspepsia ◽  
Healthcare Consumption
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