Cognitive and physical factors affecting daily function in Alzheimer's disease: A cross-sectional analysis

2018 ◽  
Vol 21 (1) ◽  
pp. 14-20 ◽  
Author(s):  
Fang Yu ◽  
Yan Chen ◽  
Michelle A. Mathiason ◽  
Qiaoqin Wan ◽  
Feng V. Lin
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Physical Factors ◽  
Cross Sectional ◽  
Factors Affecting ◽  
Cross Sectional Analysis ◽  
Sectional Analysis ◽  
Daily Function

P-042: Preliminary cross-sectional analysis of pet data from the Alzheimer's disease neuroimaging initiative using morphometry birn procedures

2007 ◽  
Vol 3 (3S_Part_1) ◽  
pp. S110-S110
Author(s):  
David S. Karow ◽  
Donald J. Hagler ◽  
Christine Fennema-Notestine ◽  
Linda K. McEvoy ◽  
Elaine H. Wu ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cross Sectional ◽  
Cross Sectional Analysis ◽  
Sectional Analysis

Longitudinal and cross-sectional analysis of atrophy in Alzheimer's disease: Cross-validation of BSI, SIENA and SIENAX

NeuroImage ◽  
2007 ◽  
Vol 36 (4) ◽  
pp. 1200-1206 ◽  
Author(s):  
Stephen M. Smith ◽  
Anil Rao ◽  
Nicola De Stefano ◽  
Mark Jenkinson ◽  
Jonathan M. Schott ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cross Validation ◽  
Cross Sectional ◽  
Cross Sectional Analysis ◽  
Sectional Analysis

scholarly journals Quality of life and factors affecting it in patients with Alzheimer’s disease: a cross-sectional study

2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Burcu Akpınar Söylemez ◽  
Özlem Küçükgüçlü ◽  
Merve Aliye Akyol ◽  
Ahmet Turan Işık
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Affecting ◽  
Area Of Interest ◽  
Modifiable Factors

Abstract Background Quality of life (QoL) is a growing area of interest in dementia research. However, it remains a controversial topic. This study aimed to determine the QoL of people with Alzheimer’s disease (PwAD) and investigate the factors affecting patients’ and caregivers’ QoL scores. Methods A cross-sectional study design was used. A total of 98 home-dwelling PwADs and their primary caregivers were recruited in the study. Sociodemographic characteristics and QoL scores, activities of daily living (ADL) and instrumental ADL (IADL), Mini-mental State Examination (MMSE) scores, neuropsychiatric inventory (NPI), and NPI–distress were determined to assess the relevant outcomes. All statistical analyses were performed using SPSS version 22.0. Descriptive statistics, t-test, Pearson correlation, and multinomial regression were used for analysis. Results The patients’ ratings of their QoL were higher than those of the caregivers. Caregiver education, patients’ ADL, and IADL were associated with the patients’ score on the Quality of Life in Alzheimer’s Disease (QoL-AD) scale. In addition to these variables, MMSE, NPI, and NPI–distress were associated with the caregiver scores on QoL-AD. Conclusion From a clinical point of view, the proxy-rated scores of QoL cannot replace the self-ratings of the patients. This study suggests that both self- and proxy-rated QoL scores should be applied whenever possible. Focusing on the management of behavioral problems and supporting functionality and cognitive functions may be modifiable factors that may represent targets for intervention to improve the QoL. The findings of this study should also be used to design caregiver educational programs about the determinants of QoL.

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