Novel case of recurrent intraventricular atypical central neurocytoma with prominent gangliogliomatous differentiation in a 10-year-old boy with 10 years of follow up

2018 ◽  
Vol 38 (5) ◽  
pp. 542-548
Author(s):  
Char-Loo Tan ◽  
Daniel Landi ◽  
Herbert Fuchs ◽  
Roger E. McLendon
Keyword(s):  
Central Neurocytoma ◽  
Atypical Central Neurocytoma

Tetraventricular Atypical Central Neurocytoma

2019 ◽  
Vol 122 ◽  
pp. 454-457 ◽  
Author(s):  
Vikas Singh ◽  
Ashwin Borkar ◽  
Aliasgar Moiyadi ◽  
Prakash Shetty
Keyword(s):  
Central Neurocytoma ◽  
Atypical Central Neurocytoma

Atypical central neurocytoma with metastatic craniospinal dissemination: a case report

2016 ◽  
Vol 40 (6) ◽  
pp. 1108-1111 ◽  
Author(s):  
Megha Nayyar ◽  
Mary Catherine Mayo ◽  
Mark Shiroishi ◽  
Deborah Commins ◽  
Charles Y. Liu ◽  
...  
Keyword(s):  
Case Report ◽  
Central Neurocytoma ◽  
Craniospinal Dissemination ◽  
Atypical Central Neurocytoma

scholarly journals Atypical Central Neurocytoma

1997 ◽  
Vol 56 (5) ◽  
pp. 551-556 ◽  
Author(s):  
FIGEN SÖYLEMEZOGLU ◽  
BERND W. SCHEITHAUER ◽  
JACQUES ESTEVE ◽  
PAUL KLEIHUES
Keyword(s):  
Central Neurocytoma ◽  
Atypical Central Neurocytoma

Central Neurocytoma

Neurosurgery ◽  
2012 ◽  
Vol 72 (3) ◽  
pp. 407-414 ◽  
Author(s):  
Jin Wook Kim ◽  
Dong Gyu Kim ◽  
In Kyeong Kim ◽  
Yong Hwy Kim ◽  
Seung Hong Choi ◽  
...  
Keyword(s):  
Overall Survival ◽  
Clinical Outcomes ◽  
Functional Outcomes ◽  
Management Strategies ◽  
Treatment Strategies ◽  
Central Neurocytoma ◽  
Tumor Control ◽  
Seizure Outcome

Abstract BACKGROUND: A thorough investigation of the long-term outcomes of central neurocytoma (CN) after different treatments is required to establish optimal management strategies. OBJECTIVE We retrospectively reviewed the long-term clinical outcomes of patients with CN according to various treatments and suggest treatment strategies based on 30 years of experience in a single institution. METHODS: Fifty-eight consecutive patients with CN were treated at our institution between 1982 and 2008. Patient demographics, overall survival, local control rates according to multimodal treatments, and functional outcomes were evaluated. The mean clinical and radiological follow-up periods were 119 months (range, 18-304 months) and 98 months (range, 13-245 months), respectively. RESULTS: The initial treatment modality was classified into 4 subgroups: operation only (34 patients), operation followed by radiation therapy (7 patients) or radiosurgery (7 patients), and radiosurgery alone (10 patients). The actuarial overall survival was 91% at 5 years and 88% at 10 years. The actuarial overall survival and local tumor control rate did not differ significantly according to the various treatments and the initial extent of the surgical resection. However, functional outcomes, such as the postoperative seizure outcome at the last follow-up, differed according to the surgical approach. CONCLUSION: The long-term clinical outcomes of CN after multimodal treatment seem to be excellent. Our study suggests that treatment strategies for CN should focus on the patient's quality of life, as well as on tumor control, because of the benign nature of CN.

scholarly journals Atypical central neurocytoma with leptomeningeal dissemination: a case report

2020 ◽  
Vol 32 (1) ◽  
Author(s):  
Shikha Goyal ◽  
Tejinder Kataria ◽  
Deepak Gupta ◽  
Aruj Dhyani ◽  
Ishani Mohapatra ◽  
...  
Keyword(s):  
Case Report ◽  
Central Neurocytoma ◽  
Leptomeningeal Dissemination ◽  
Atypical Central Neurocytoma

scholarly journals Clinical Outcome After Microsurgical Resection of Central Neurocytoma: A Single-Centre Analysis of 15 Years

2021 ◽  
Vol 12 ◽  
Author(s):  
Dan Cao ◽  
Yong Chen ◽  
Zhengqian Guo ◽  
Yibo Ou ◽  
Jian Chen
Keyword(s):  
Overall Survival ◽  
Progression Free Survival ◽  
Extent Of Resection ◽  
Central Neurocytoma ◽  
Complication Rates ◽  
Long Term Outcome ◽  
Free Survival ◽  
Risk Of Death

Objective: This study aimed to explore the immediate postoperative and long-term outcomes of central neurocytoma (CN) based on 15 years of experience in our institution.Methods: This single-institution study collected data of 43 patients with CN who underwent surgery between 2005 and 2020. We reviewed data of clinical, immediate postoperative outcome, and long-term outcome of patients. More specifically, we divided complications into neurological and regional complications groups.Results: Among the 43 patients with CN who underwent surgery, the transcortical (72.1%) or transcallosal (25.6%) approach was used. There were 18 patients (41.9%) who complained about postoperative neurological complications, including motor weakness (25.6%), memory deficit (18.6%), aphasia (7.0%), and seizure (4.7%). In addition, 18 patients suffered postoperative regional complications such as hydrocephalus (2.3%), hematoma (34.9%), infection (4.7%), and subcutaneous hydrops (2.3%). Only one-quarter of patients had suffered permanent surgical complications. The majority of patients recovered from the deficit and could turn back to normal life. There were no significant differences in the clinical outcomes between transcortical and transcallosal approaches. At a median follow-up of 61.8 months, the 5-year overall survival and progression-free survival were 87.0 and 74.0%, respectively. A multivariate Cox model analysis showed that the extent of resection was not related to progression-free survival. However, the extent of resection was significantly associated with overall survival, and gross total resection decreased the risk of death.Conclusions: Patients with CN show favorable outcomes after surgery. The transcortical and transcallosal approaches have similar postoperative complication rates and long-term follow-up outcomes. In terms of long-term prognosis, maximal safety resection should be the first choice of CN.

The importance of staged surgery for giant atypical central neurocytoma

2020 ◽  
Author(s):  
Jennyfer Paulla Galdino Chaves ◽  
Carlos Alberto Mattozo ◽  
Bruno Augusto Telles ◽  
Ana Paula Percicote ◽  
Zeferino Jr Demartini ◽  
...  
Keyword(s):  
Central Neurocytoma ◽  
Staged Surgery ◽  
Atypical Central Neurocytoma

scholarly journals Atypical Central Neurocytoma With Sarcomatous Differentiation

2014 ◽  
Vol 138 (9) ◽  
pp. 1233-1237 ◽  
Author(s):  
Lakshmi Vemavarapu ◽  
Irene Czyszczon ◽  
Joseph C. Parker ◽  
Stephanie Wagner ◽  
Todd Vitaz ◽  
...  
Keyword(s):  
Spindle Cell ◽  
Central Neurocytoma ◽  
Proliferation Index ◽  
Sarcomatous Component ◽  
Ki 67 ◽  
Spindle Cells ◽  
Left Lateral Ventricle ◽  
Mitotic Figures ◽  
Occipital Horn ◽  
Atypical Central Neurocytoma

We report a case of an intraventricular tumor with features of atypical central neurocytoma with a sarcomatous component in a 44-year-old woman who presented with headaches and vomiting. Magnetic resonance imaging revealed a 3.4-cm lobulated enhancing mass in the occipital horn of the left lateral ventricle, and the patient subsequently underwent a left occipital-parietal craniotomy for debulking. The tumor contained 2 cell populations: round cells with perinuclear halos in a fibrillary background, and spindle cells with oval nuclei arranged in interlacing fascicles with focal necrosis. The round cells had diffuse synaptophysin immunopositivity, while the spindle cells were diffusely immunopositive for vimentin and had intercellular reticulin. The mitotic activity (8 mitotic figures per 10 high-power fields) and the high Ki-67 proliferation index (15.0%) were consistent with atypical central neurocytoma with a sarcomatous component. Although different histologic variants have been described, this is the first reported case, to our knowledge, of central neurocytoma with spindle cell sarcomatous features.

Central neurocytoma: long-term follow-up of a paediatric case

2000 ◽  
Vol 7 (6) ◽  
pp. 548-552 ◽  
Author(s):  
Leonello Tacconi ◽  
Marco Rossi ◽  
Patrick Foy
Keyword(s):  
Central Neurocytoma ◽  
Paediatric Case ◽  
Long Term Follow Up
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